Q6P8X1: Sorting nexin-6

General Information

Protein names	- Sorting nexin-6 - Sorting nexin-6, N-terminally processed
Gene names	Snx6
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6P8X1

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MMEGLDDGPD FLSEEDRGLK AINVDLQSDA ALQVDISDAL SERDRVKFTV HTKSSLPNFK
        70         80         90        100        110        120
QNEFSVVRQH EEFIWLHDSF VENEDYAGYI IPPAPPRPDF DASREKLQKL GEGEGSMTKE
       130        140        150        160        170        180
EFTKMKQELE AEYLAIFKKT VAMHEVFLCR VAAHPILRKD LNFHVFLEYN QDLSVRGKNK
       190        200        210        220        230        240
KEKLEDFFKN MVKSADGVIV SGVKDVDDFF EHERTFLLEY HNRVKDASAK SDRMTRSHKS
       250        260        270        280        290        300
AADDYNRIGS SLYALGTQDS TDICKFFLKV SELFDKTRKI EARVSADEDL KLSDLLKYYL
       310        320        330        340        350        360
RESQAAKDLL YRRSRSLVDY ENANKALDKA RAKNKDVLQA ETSQQLCCQK FEKISESAKQ
       370        380        390        400
ELIDFKTRRV AAFRKNLVEL AELELKHAKG NLQLLQNCLA VLNGDT

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q6P8X1-1-Acetylation	MMEGLD...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q6P8X1-2-Acetylation	MEGLDD...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q6P8X1-2-Acetylation	MEGLDD...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q6P8X1-54-unmodified	SSLPNF...	54			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q6P8X1-203-unknown	VKDVDD...	203		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34021

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...VIVSGV	202	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34021
	...LNGDT	406	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	202	VSGV.\|.VKDV	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)