Q6P9R2: Serine/threonine-protein kinase OSR1

General Information

Protein names	- Serine/threonine-protein kinase OSR1 - 2.7.11.1 - Oxidative stress-responsive 1 protein
Gene names	Oxsr1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6P9R2

5 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSEDSSALPW SINRDDYELQ EVIGSGATAV VQAAYCAPKK ERVAIKRINL EKCQTSMDEL
        70         80         90        100        110        120
LKEIQAMSQC HHPNIVSYYT SFVVKDELWL VMKLLSGGSV LDIIKHIVAK GEHKSGVLDE
       130        140        150        160        170        180
PTIATILREV LEGLEYLHKN GQIHRDVKAG NILLGEDGSV QIADFGVSAF LATGGDITRN
       190        200        210        220        230        240
KVRKTFVGTP CWMAPEVMEQ VRGYDFKADI WSFGITAIEL ATGAAPYHKY PPMKVLMLTL
       250        260        270        280        290        300
QNDPPSLETG VQDKEMLKKY GKSFRKMISL CLQKDPEKRP TAAELLRHKF FQKAKNKEFL
       310        320        330        340        350        360
QEKILQRAPT ISERSKKVRR VPGSSGRLHK TEDGGWEWSD DEFDEESEEG RAAISQLRSP
       370        380        390        400        410        420
RVKDSLSSSE LFAAAEPMGT LLQVPEQISA HLPQPAGQMP TQPAQVSLLP PAEPAKPAQA
       430        440        450        460        470        480
QSSGERSQET KIPISLVLRL RNSKKELNDI RFEFTPGRDT AEGVSQELIS AGLVDGRDLV
       490        500        510        520
IVAANLQKIV EEPQSNRSVT FKLASGVEGS DIPDDGKLIG FAQLSIS

Isoforms

Sequence View

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q6P9R2-2-unknown	MSEDSS...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q6P9R2-2-unknown	MSEDSS...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q6P9R2-2-Acetylation	SEDSSA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q6P9R2-2-Acetylation	SEDSSA...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q6P9R2-20-unknown	QEVIGS...	20		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30619
Q6P9R2-170-unknown	FLATGG...	170		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34022
Q6P9R2-484-unknown	ANLQKI...	484		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30620

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DDYELQ	19	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30619
...FGVSAF	169	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34022
...LVIVAA	483	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30620
...QLSIS	527	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	19	YELQ.\|.QEVI	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> OXSR1_MOUSE @19
MMP2_MOUSE	169	VSAF.\|.FLAT	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	483	IVAA.\|.ANLQ	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> OXSR1_MOUSE @483

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)