Q6PJG6: BRCA1-associated ATM activator 1

General Information

Protein names	- BRCA1-associated ATM activator 1 - BRCA1-associated protein required for ATM activation protein 1
Gene names	BRAT1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6PJG6

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDPECAQLLP ALCAVLVDPR QPVADDTCLE KLLDWFKTVT EGESSVVLLQ EHPCLVELLS
        70         80         90        100        110        120
HVLKVQDLSS GVLSFSLRLA GTFAAQENCF QYLQQGELLP GLFGEPGPLG RATWAVPTVR
       130        140        150        160        170        180
SGWIQGLRSL AQHPSALRFL ADHGAVDTIF SLQGDSSLFV ASAASQLLVH VLALSMRGGA
       190        200        210        220        230        240
EGQPCLPGGD WPACAQKIMD HVEESLCSAA TPKVTQALNV LTTTFGRCQS PWTEALWVRL
       250        260        270        280        290        300
SPRVACLLER DPIPAAHSFV DLLLCVARSP VFSSSDGSLW ETVARALSCL GPTHMGPLAL
       310        320        330        340        350        360
GILKLEHCPQ ALRTQAFQVL LQPLACVLKA TVQAPGPPGL LDGTADDATT VDTLLASKSS
       370        380        390        400        410        420
CAGLLCRTLA HLEELQPLPQ RPSPWPQASL LGATVTVLRL CDGSAAPASS VGGHLCGTLA
       430        440        450        460        470        480
GCVRVQRAAL DFLGTLSQGT GPQELVTQAL AVLLECLESP GSSPTVLKKA FQATLRWLLS
       490        500        510        520        530        540
SPKTPGCSDL GPLIPQFLRE LFPVLQKRLC HPCWEVRDSA LEFLTQLSRH WGGQADFRCA
       550        560        570        580        590        600
LLASEVPQLA LQLLQDPESY VRASAVTAMG QLSSQGLHAP TSPEHAEARQ SLFLELLHIL
       610        620        630        640        650        660
SVDSEGFPRR AVMQVFTEWL RDGHADAAQD TEQFVATVLQ AASRDLDWEV RAQGLELALV
       670        680        690        700        710        720
FLGQTLGPPR THCPYAVALP EVAPAQPLTE ALRALCHVGL FDFAFCALFD CDRPVAQKSC
       730        740        750        760        770        780
DLLLFLRDKI ASYSSLREAR GSPNTASAEA TLPRWRAGEQ AQPPGDQEPE AVLAMLRSLD
       790        800        810        820
LEGLRSTLAE SSDHVEKSPQ SLLQDMLATG GFLQGDEADC Y

Isoforms

- Isoform 2 of BRCA1-associated ATM activator 1 - Isoform 3 of BRCA1-associated ATM activator 1

Sequence View

        10         20         30         40         50         60
MDPECAQLLP ALCAVLVDPR QPVADDTCLE KLLDWFKTVT EGESSVVLLQ EHPCLVELLS
        70         80         90        100        110        120
HVLKVQDLSS GVLSFSLRLA GTFAAQENCF QYLQQGELLP GLFGEPGPLG RATWAVPTVR
       130        140        150        160        170        180
SGWIQGLRSL AQHPSALRFL ADHGAVDTIF SLQGDSSLFV ASAASQLLVH VLALSMRGGA
       190        200        210        220        230        240
EGQPCLPGGD WPACAQKIMD HVEESLCSAA TPKVTQALNV LTTTFGRCQS PWTEALWVRL
       250        260        270        280        290        300
SPRVACLLER DPIPAAHSFV DLLLCVARSP VFSSSDGSLW ETVARALSCL GPTHMGPLAL
       310        320        330        340        350        360
GILKLEHCPQ ALRTQAFQVL LQPLACVLKA TVQAPGPPGL LDGTADDATT VDTLLASKSS
       370        380        390        400        410        420
CAGLLCRTLA HLEELQPLPQ RPSPWPQASL LGATVTVLRL CDGSAAPASS VGGHLCGTLA
       430        440        450        460        470        480
GCVRVQRAAL DFLGTLSQGT GPQELVTQAL AVLLECLESP GSSPTVLKKA FQATLRWLLS
       490        500        510        520        530        540
SPKTPGCSDL GPLIPQFLRE LFPVLQKRLC HPCWEVRDSA LEFLTQLSRH WGGQADFRCA
       550        560        570        580        590        600
LLASEVPQLA LQLLQDPESY VRASAVTAMG QLSSQGLHAP TSPEHAEARQ SLFLELLHIL
       610        620        630        640        650        660
SVDSEGFPRR AVMQVFTEWL RDGHADAAQD TEQFVATVLQ AASRDLDWEV RAQGLELALV
       670        680        690        700        710        720
FLGQTLGPPR THCPYAVALP EVAPAQPLTE ALRALCHVGL FDFAFCALFD CDRPVAQKSC
       730        740        750        760        770        780
DLLLFLRDKI ASYSSLREAR GSPNTASAEA TLPRWRAGEQ AQPPGDQEPE AVLAMLRSLD
       790        800        810        820
LEGLRSTLAE SSDHVEKSPQ SLLQDMLATG GFLQGDEADC Y         10         20         30         40         50         60
MDPECAQLLP ALCAVLVDPR QPVADDTCLE KLLDWFKTVT EGESSVVLLQ EHPCLVELLS
        70         80         90        100        110        120
HVLKVQDLSS GVLSFSLRLA GTFAAQENCF QYLQQGELLP GLFGEPGPLG RATWAVPTVR
       130        140        150        160        170        180
SGWIQGLRSL AQHPSALRFL ADHGAVDTIF SLQGDSSLFV ASAASQLLVH VLALSMRGGA
       190        200        210        220        230        240
EGQPCLPGGD WPACAQKIMD HVEESLCSAA TPKVTQALNV LTTTFGRCQS PWTEALWVRL
       250        260        270        280        290        300
SPRVACLLER DPIPAAHSFV DLLLCVARSP VFSSSDGSLW ETVARALSCL GPTHMGPLAL
       310        320        330        340        350        360
GILKLEHCPQ ALRTQAFQVL LQPLACVLKA TVQAPGPPGL LDGTADDATT VDTLLASKSS
       370        380        390        400        410        420
CAGLLCRTLA HLEELQPLPQ RPSPWPQASL LGATVTVLRL CDGSAAPASS VGGHLCGTLA
       430        440        450        460        470        480
GCVRVQRAAL DFLGTLSQGT GPQELVTQAL AVLLECLESP GSSPTVLKKA FQATLRWLLS
       490        500        510        520        530        540
SPKTPGCSDL GPLIPQFLRE LFPVLQKRLC HPCWEVRDSA LEFLTQLSRH WGGQADFRCA
       550        560        570        580        590        600
LLASEVPQLA LQLLQDPESY VRASAVTAMG QLSSQGLHAP TSPEHAEARQ SLFLELLHIL
       610        620        630        640        650        660
SVDSEGFPRR AVMQVFTEWL RDGHADAAQD TEQFVATVLQ AASRDLDWEV RAQGLELALV
       670        680        690        700        710        720
FLGQTLGPPR THCPYAVALP EVAPAQPLTE ALRALCHVGL FDFAFCALFD CDRPVAQKSC
       730        740        750        760        770        780
DLLLFLRDKI ASYSSLREAR GSPNTASAEA TLPRWRAGEQ AQPPGDQEPE AVLAMLRSLD
       790        800        810        820
LEGLRSTLAE SSDHVEKSPQ SLLQDMLATG GFLQGDEADC Y

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q6PJG6-1-acetylation	MDPECA...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q6PJG6-1-acetylation	MDPECA...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q6PJG6-1-acetylation	MDPECA...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162629
Q6PJG6-1-unknown	MDPECA...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q6PJG6-1-unknown	MDPECA...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt68589
Q6PJG6-579-unknown	APTSPE...	579		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6557

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SQGLHA	578	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6557
...EADCY	821	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EADCY	821	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt64208

TopFIND

Q6PJG6: BRCA1-associated ATM activator 1

General Information

3

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates