Q6ZNE5: Beclin 1-associated autophagy-related key regulator {ECO:0000303|PubMed:19050071}

General Information

Protein names	- Beclin 1-associated autophagy-related key regulator {ECO:0000303\|PubMed:19050071} - Barkor {ECO:0000303\|PubMed:19050071} - Autophagy-related protein 14-like protein {ECO:0000303\|PubMed:19270696} - Atg14L {ECO:0000303\|PubMed:19270696}
Gene names	ATG14
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6ZNE5

6 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MASPSGKGAR ALEAPGCGPR PLARDLVDSV DDAEGLYVAV ERCPLCNTTR RRLTCAKCVQ
        70         80         90        100        110        120
SGDFVYFDGR DRERFIDKKE RLSRLKSKQE EFQKEVLKAM EGKWITDQLR WKIMSCKMRI
       130        140        150        160        170        180
EQLKQTICKG NEEMEKNSEG LLKTKEKNQK LYSRAQRHQE KKEKIQRHNR KLGDLVEKKT
       190        200        210        220        230        240
IDLRSHYERL ANLRRSHILE LTSVIFPIEE VKTGVRDPAD VSSESDSAMT SSTVSKLAEA
       250        260        270        280        290        300
RRTTYLSGRW VCDDHNGDTS ISITGPWISL PNNGDYSAYY SWVEEKKTTQ GPDMEQSNPA
       310        320        330        340        350        360
YTISAALCYA TQLVNILSHI LDVNLPKKLC NSEFCGENLS KQKFTRAVKK LNANILYLCF
       370        380        390        400        410        420
SQHVNLDQLQ PLHTLRNLMY LVSPSSEHLG RSGPFEVRAD LEESMEFVDP GVAGESDESG
       430        440        450        460        470        480
DERVSDEETD LGTDWENLPS PRFCDIPSQS VEVSQSQSTQ ASPPIASSSA GGMISSAAAS
       490
VTSWFKAYTG HR

Isoforms

- Isoform 2 of Beclin 1-associated autophagy-related key regulator

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q6ZNE5-1-unknown	MASPSG...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q6ZNE5-2-acetylation	ASPSGK...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q6ZNE5-2-acetylation	ASPSGK...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q6ZNE5-29-	SVDDAE...	29			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q6ZNE5-114-unknown	MSCKMR...	114		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt68195
Q6ZNE5-227-unknown	SAMTSS...	227		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt165753
Q6ZNE5-227-	SAMTSS...	227			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...YTGHR	492	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...YTGHR	492	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt63813

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)