Q6ZVM7: TOM1-like protein 2

General Information

Protein names	- TOM1-like protein 2 - Target of Myb-like protein 2
Gene names	TOM1L2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6ZVM7

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of TOM1-like protein 2 - Isoform 3 of TOM1-like protein 2 - Isoform 4 of TOM1-like protein 2 - Isoform 5 of TOM1-like protein 2

Sequence View

        10         20         30         40         50         60
MEFLLGNPFS TPVGQCLEKA TDGSLQSEDW TLNMEICDII NETEEGPKDA IRALKKRLNG
        70         80         90        100        110        120
NRNYREVMLA LTVLETCVKN CGHRFHILVA NRDFIDSVLV KIISPKNNPP TIVQDKVLAL
       130        140        150        160        170        180
IQAWADAFRS SPDLTGVVHI YEELKRKGVE FPMADLDALS PIHTPQRSVP EVDPAATMPR
       190        200        210        220        230        240
SQSQQRTSAG SYSSPPPAPY SAPQAPALSV TGPITANSEQ IARLRSELDV VRGNTKVMSE
       250        260        270        280        290        300
MLTEMVPGQE DSSDLELLQE LNRTCRAMQQ RIVELISRVS NEEVTEELLH VNDDLNNVFL
       310        320        330        340        350        360
RYERFERYRS GRSVQNASNG VLNEVTEDNL IDLGPGSPAV VSPMVGNTAP PSSLSSQLAG
       370        380        390        400        410        420
LDLGTESVSG TLSSLQQCNP RDGFDMFAQT RGNSLAEQRK TVTYEDPQAV GGLASALDNR
       430        440        450        460        470        480
KQSSEGIPVA QPSVMDDIEV WLRTDLKGDD LEEGVTSEEF DKFLEERAKA AEMVPDLPSP
       490        500
PMEAPAPASN PSGRKKPERS EDALFAL         10         20         30         40         50         60
MEFLLGNPFS TPVGQCLEKA TDGSLQSEDW TLNMEICDII NETEEGPKDA IRALKKRLNG
        70         80         90        100        110        120
NRNYREVMLA LTVLETCVKN CGHRFHILVA NRDFIDSVLV KIISPKNNPP TIVQDKVLAL
       130        140        150        160        170        180
IQAWADAFRS SPDLTGVVHI YEELKRKGVE FPMADLDALS PIHTPQRSVP EVDPAATMPR
       190        200        210        220        230        240
SQSQQRTSAG SYSSPPPAPY SAPQAPALSV TGPITANSEQ IARLRSELDV VRGNTKVMSE
       250        260        270        280        290        300
MLTEMVPGQE DSSDLELLQE LNRTCRAMQQ RIVELISRVS NEEVTEELLH VNDDLNNVFL
       310        320        330        340        350        360
RYERFERYRS GRSVQNASNG VLNEVTEDNL IDLGPGSPAV VSPMVGNTAP PSSLSSQLAG
       370        380        390        400        410        420
LDLGTESVSG TLSSLQQCNP RDGFDMFAQT RGNSLAEQRK TVTYEDPQAV GGLASALDNR
       430        440        450        460        470        480
KQSSEGIPVA QPSVMDDIEV WLRTDLKGDD LEEGVTSEEF DKFLEERAKA AEMVPDLPSP
       490        500
PMEAPAPASN PSGRKKPERS EDALFAL         10         20         30         40         50         60
MEFLLGNPFS TPVGQCLEKA TDGSLQSEDW TLNMEICDII NETEEGPKDA IRALKKRLNG
        70         80         90        100        110        120
NRNYREVMLA LTVLETCVKN CGHRFHILVA NRDFIDSVLV KIISPKNNPP TIVQDKVLAL
       130        140        150        160        170        180
IQAWADAFRS SPDLTGVVHI YEELKRKGVE FPMADLDALS PIHTPQRSVP EVDPAATMPR
       190        200        210        220        230        240
SQSQQRTSAG SYSSPPPAPY SAPQAPALSV TGPITANSEQ IARLRSELDV VRGNTKVMSE
       250        260        270        280        290        300
MLTEMVPGQE DSSDLELLQE LNRTCRAMQQ RIVELISRVS NEEVTEELLH VNDDLNNVFL
       310        320        330        340        350        360
RYERFERYRS GRSVQNASNG VLNEVTEDNL IDLGPGSPAV VSPMVGNTAP PSSLSSQLAG
       370        380        390        400        410        420
LDLGTESVSG TLSSLQQCNP RDGFDMFAQT RGNSLAEQRK TVTYEDPQAV GGLASALDNR
       430        440        450        460        470        480
KQSSEGIPVA QPSVMDDIEV WLRTDLKGDD LEEGVTSEEF DKFLEERAKA AEMVPDLPSP
       490        500
PMEAPAPASN PSGRKKPERS EDALFAL         10         20         30         40         50         60
MEFLLGNPFS TPVGQCLEKA TDGSLQSEDW TLNMEICDII NETEEGPKDA IRALKKRLNG
        70         80         90        100        110        120
NRNYREVMLA LTVLETCVKN CGHRFHILVA NRDFIDSVLV KIISPKNNPP TIVQDKVLAL
       130        140        150        160        170        180
IQAWADAFRS SPDLTGVVHI YEELKRKGVE FPMADLDALS PIHTPQRSVP EVDPAATMPR
       190        200        210        220        230        240
SQSQQRTSAG SYSSPPPAPY SAPQAPALSV TGPITANSEQ IARLRSELDV VRGNTKVMSE
       250        260        270        280        290        300
MLTEMVPGQE DSSDLELLQE LNRTCRAMQQ RIVELISRVS NEEVTEELLH VNDDLNNVFL
       310        320        330        340        350        360
RYERFERYRS GRSVQNASNG VLNEVTEDNL IDLGPGSPAV VSPMVGNTAP PSSLSSQLAG
       370        380        390        400        410        420
LDLGTESVSG TLSSLQQCNP RDGFDMFAQT RGNSLAEQRK TVTYEDPQAV GGLASALDNR
       430        440        450        460        470        480
KQSSEGIPVA QPSVMDDIEV WLRTDLKGDD LEEGVTSEEF DKFLEERAKA AEMVPDLPSP
       490        500
PMEAPAPASN PSGRKKPERS EDALFAL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q6ZVM7-1-unknown	MEFLLG...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q6ZVM7-1-unknown	MEFLLG...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt92331
Q6ZVM7-1-unknown	MEFLLG...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt92332
Q6ZVM7-158-	ALSPIH...	158		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q6ZVM7-158-	ALSPIH...	158		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q6ZVM7-158-	ALSPIH...	158		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q6ZVM7-158-	ALSPIH...	158		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q6ZVM7-158-	ALSPIH...	158		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q6ZVM7-158-unknown	ALSPIH...	158		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q6ZVM7-158-unknown	ALSPIH...	158	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162226
Q6ZVM7-268-unknown	MQQRIV...	268	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt92333
Q6ZVM7-268-unknown	MQQRIV...	268	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt105563
Q6ZVM7-268-unknown	MQQRIV...	268	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt105562

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ALFAL	507	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...ALFAL	507	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt87951
...ALFAL	507	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt87949
...ALFAL	507	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt87950

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)