Q70SY1: Cyclic AMP-responsive element-binding protein 3-like protein 2

General Information

Protein names	- Cyclic AMP-responsive element-binding protein 3-like protein 2 - cAMP-responsive element-binding protein 3-like protein 2 - BBF2 human homolog on chromosome 7 - Processed cyclic AMP-responsive element-binding protein 3-like protein 2
Gene names	CREB3L2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q70SY1

3 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Cyclic AMP-responsive element-binding protein 3-like protein 2 - Isoform 3 of Cyclic AMP-responsive element-binding protein 3-like protein 2

Sequence View

        10         20         30         40         50         60
MEVLESGEQG VLQWDRKLSE LSEPGDGEAL MYHTHFSELL DEFSQNVLGQ LLNDPFLSEK
        70         80         90        100        110        120
SVSMEVEPSP TSPAPLIQAE HSYSLCEEPR AQSPFTHITT SDSFNDDEVE SEKWYLSTDF
       130        140        150        160        170        180
PSTSIKTEPV TDEPPPGLVP SVTLTITAIS TPLEKEEPPL EMNTGVDSSC QTIIPKIKLE
       190        200        210        220        230        240
PHEVDQFLNF SPKEAPVDHL HLPPTPPSSH GSDSEGSLSP NPRLHPFSLP QTHSPSRAAP
       250        260        270        280        290        300
RAPSALSSSP LLTAPHKLQG SGPLVLTEEE KRTLIAEGYP IPTKLPLSKS EEKALKKIRR
       310        320        330        340        350        360
KIKNKISAQE SRRKKKEYMD SLEKKVESCS TENLELRKKV EVLENTNRTL LQQLQKLQTL
       370        380        390        400        410        420
VMGKVSRTCK LAGTQTGTCL MVVVLCFAVA FGSFFQGYGP YPSATKMALP SQHSLQEPYT
       430        440        450        460        470        480
ASVVRSRNLL IYEEHSPPEE SSSPGSAGEL GGWDRGSSLL RVSGLESRPD VDLPHFIISN
       490        500        510        520
ETSLEKSVLL ELQQHLVSAK LEGNETLKVV ELDRRVNTTF         10         20         30         40         50         60
MEVLESGEQG VLQWDRKLSE LSEPGDGEAL MYHTHFSELL DEFSQNVLGQ LLNDPFLSEK
        70         80         90        100        110        120
SVSMEVEPSP TSPAPLIQAE HSYSLCEEPR AQSPFTHITT SDSFNDDEVE SEKWYLSTDF
       130        140        150        160        170        180
PSTSIKTEPV TDEPPPGLVP SVTLTITAIS TPLEKEEPPL EMNTGVDSSC QTIIPKIKLE
       190        200        210        220        230        240
PHEVDQFLNF SPKEAPVDHL HLPPTPPSSH GSDSEGSLSP NPRLHPFSLP QTHSPSRAAP
       250        260        270        280        290        300
RAPSALSSSP LLTAPHKLQG SGPLVLTEEE KRTLIAEGYP IPTKLPLSKS EEKALKKIRR
       310        320        330        340        350        360
KIKNKISAQE SRRKKKEYMD SLEKKVESCS TENLELRKKV EVLENTNRTL LQQLQKLQTL
       370        380        390        400        410        420
VMGKVSRTCK LAGTQTGTCL MVVVLCFAVA FGSFFQGYGP YPSATKMALP SQHSLQEPYT
       430        440        450        460        470        480
ASVVRSRNLL IYEEHSPPEE SSSPGSAGEL GGWDRGSSLL RVSGLESRPD VDLPHFIISN
       490        500        510        520
ETSLEKSVLL ELQQHLVSAK LEGNETLKVV ELDRRVNTTF

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q70SY1-1-unknown	MEVLES...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q70SY1-1-unknown	MEVLES...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt71635
Q70SY1-1-unknown	MEVLES...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt71636
Q70SY1-431-	IYEEHS...	431		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q70SY1-431-unknown	IYEEHS...	431	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC16839

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...	0	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SRNLLI	430	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16839
...VNTTF	520	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MBTP1_HUMAN	430	NLLI.\|.IYEE	inferred from experiment	unknown	MEROPS	Seidah NG	Pasquato A et al.:The proprotein convertase SKI-1... (S08.063)	16790437,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)