Q7TMK9: Heterogeneous nuclear ribonucleoprotein Q

General Information

Protein names	- Heterogeneous nuclear ribonucleoprotein Q - hnRNP Q - Glycine- and tyrosine-rich RNA-binding protein - GRY-RBP - NS1-associated protein 1 - Synaptotagmin-binding, cytoplasmic RNA-interacting protein - pp68
Gene names	Syncrip
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q7TMK9

6 N-termini

5 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MATEHVNGNG TEEPMDTTSA VIHSENFQTL LDAGLPQKVA EKLDEIYVAG LVAHSDLDER
        70         80         90        100        110        120
AIEALKEFNE DGALAVLQQF KDSDLSHVQN KSAFLCGVMK TYRQREKQGT KVADSSKGPD
       130        140        150        160        170        180
EAKIKALLER TGYTLDVTTG QRKYGGPPPD SVYSGQQPSV GTEIFVGKIP RDLFEDELVP
       190        200        210        220        230        240
LFEKAGPIWD LRLMMDPLTG LNRGYAFVTF CTKEAAQEAV KLYNNHEIRS GKHIGVCISV
       250        260        270        280        290        300
ANNRLFVGSI PKSKTKEQIL EEFSKVTEGL TDVILYHQPD DKKKNRGFCF LEYEDHKTAA
       310        320        330        340        350        360
QARRRLMSGK VKVWGNVGTV EWADPIEDPD PEVMAKVKVL FVRNLANTVT EEILEKSFSQ
       370        380        390        400        410        420
FGKLERVKKL KDYAFIHFDE RDGAVKAMEE MNGKDLEGEN IEIVFAKPPD QKRKERKAQR
       430        440        450        460        470        480
QAAKNQMYDD YYYYGPPHMP PPTRGRGRGG RGGYGYPPDY YGYEDYYDYY GYDYHNYRGG
       490        500        510        520        530        540
YEDPYYGYED FQVGARGRGG RGARGAAPSR GRGAAPPRGR AGYSQRGGPG SARGVRGARG
       550        560        570        580        590        600
GAQQQRGRGV RGARGGRGGN VGGKRKADGY NQPDTKRRQT NNQNWGSQPI AQQPLQGGDH
       610        620
SGNYGYKSEN QEFYQDTFGQ QWK

Isoforms

- Isoform 2 of Heterogeneous nuclear ribonucleoprotein Q

Sequence View

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Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

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Evidence Names:

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Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 5 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q7TMK9-2-unknown	MATEHV...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q7TMK9-2-unknown	MATEHV...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q7TMK9-1-unknown	MATEHV...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77186
Q7TMK9-2-Acetylation	ATEHVN...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q7TMK9-2-Acetylation	ATEHVN...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110083
Q7TMK9-2-Acetylation	ATEHVN...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q7TMK9-51-unknown	LVAHSD...	51		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34041
Q7TMK9-51-unknown	LVAHSD...	51		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt139298
Q7TMK9-99-unknown	MKTYRQ...	99		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000134342
Q7TMK9-99-unknown	MKTYRQ...	99		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196940
Q7TMK9-152-unknown	VYSGQQ...	152		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34043
Q7TMK9-152-unknown	VYSGQQ...	152		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt144840

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...IYVAGL	50	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34041
...IYVAGL	50	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122373
...NKSAFL	94	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000133292
...NKSAFL	94	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154297
...PPPDSV	151	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34043
...PPPDSV	151	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt128116
...RLMMDP	196	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000133343
...RLMMDP	196	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155566
...GQQWK	623	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	50	VAGL.\|.LVAH	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,
MMP2_MOUSE	151	PDSV.\|.VYSG	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)