Q7Z4H3: HD domain-containing protein 2

General Information

Protein names	- HD domain-containing protein 2 - Hepatitis C virus NS5A-transactivated protein 2 - HCV NS5A-transactivated protein 2
Gene names	HDDC2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q7Z4H3

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of HD domain-containing protein 2 - Isoform 3 of HD domain-containing protein 2

Sequence View

        10         20         30         40         50         60
MASVSSATFS GHGARSLLQF LRLVGQLKRV PRTGWVYRNV QRPESVSDHM YRMAVMAMVI
        70         80         90        100        110        120
KDDRLNKDRC VRLALVHDMA ECIVGDIAPA DNIPKEEKHR REEEAMKQIT QLLPEDLRKE
       130        140        150        160        170        180
LYELWEEYET QSSAEAKFVK QLDQCEMILQ ASEYEDLEHK PGRLQDFYDS TAGKFNHPEI
       190        200
VQLVSELEAE RSTNIAAAAS EPHS         10         20         30         40         50         60
MASVSSATFS GHGARSLLQF LRLVGQLKRV PRTGWVYRNV QRPESVSDHM YRMAVMAMVI
        70         80         90        100        110        120
KDDRLNKDRC VRLALVHDMA ECIVGDIAPA DNIPKEEKHR REEEAMKQIT QLLPEDLRKE
       130        140        150        160        170        180
LYELWEEYET QSSAEAKFVK QLDQCEMILQ ASEYEDLEHK PGRLQDFYDS TAGKFNHPEI
       190        200
VQLVSELEAE RSTNIAAAAS EPHS

Filter Information:

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name
Q7Z4H3-1-unknown	MASVSS...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt76839
Q7Z4H3-1-unknown	MASVSS...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt76840
Q7Z4H3-2-unknown	MASVSS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q7Z4H3-2-Acetylation	ASVSSA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q7Z4H3-2-Acetylation	ASVSSA...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q7Z4H3-2-Acetylation	ASVSSA...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110940
Q7Z4H3-2-Acetylation	ASVSSA...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110941

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...SEPHS	204	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...SEPHS	204	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt72457
...SEPHS	204		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...SEPHS	204		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)