Q7Z5J8: Ankyrin and armadillo repeat-containing protein

General Information

Protein names	- Ankyrin and armadillo repeat-containing protein
Gene names	ANKAR
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q7Z5J8

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MLRLPKKGLP RFEQVQDEDT YLENLAIQRN ASAFFEKYDR SEIQELLTTA LVSWLSAKED
        70         80         90        100        110        120
VRSQVDLPCG IMSQMNNVGF STAILLTPVD PTALLDYREV HQMIRELAIG IYCLNQIPSI
       130        140        150        160        170        180
SLEANYDQSS SCQLPPAYYD TRIGQILINI DYMLKALWHG IYMPKEKRAR FSELWRAIMD
       190        200        210        220        230        240
IDPDGKPQTN KDIFSEFSSA GLTDITKDPD FNEIYDEDVN EDPTYDPNSP EETAVFMKYA
       250        260        270        280        290        300
ENIMLKLTFS TTQIQQYENV FIFETGYWLT NAIKYNQDYL DICTYQRLQQ RLYLQKKIIQ
       310        320        330        340        350        360
KHFEKKKDIR RGIGYLKLIC FLIPFLLSLK KKMKVPYLSS LLQPFSDDKV KTERELPPFI
       370        380        390        400        410        420
YGRDFKCQNF HYKENQYFHV HGGIEFDIST PSIENALEDF QKNLEKIRDC AANTFIEDSG
       430        440        450        460        470        480
YKEYYSIPVM EFHGKSYYVI YFELETFYQQ LYKTQWWGAI NEIVNNLRLK RLPLTDAQLH
       490        500        510        520        530        540
EQFKKKLGFK RAMKCKSIPF GMKSAVERGL SAVFHTFSRK TSSSTINVSD EAGYTIFHHA
       550        560        570        580        590        600
ALHNRVSIIC QLCNANFKVN QRRFVTFSQG PTPLHLAAQA CSLETTVCLL CSKADYTLSE
       610        620        630        640        650        660
KRGWMPIHFA AFYDNVCIII ALCRKDPSLL EAEATAENQC TPLLLAATSG ALDTIQYLFS
       670        680        690        700        710        720
IGANWRKTDI KGNNIIHLSV LTFHTEVLKY IIKLNIPELP VWKTLVEMLQ CESYKRRMMA
       730        740        750        760        770        780
VMSLEVICLA NDQYWRCILD AGTIPALINL LKSSKIKLQC KTVGLLSNIS THKSAVHALV
       790        800        810        820        830        840
EAGGIPSLIN LLVCDEPEVH SRCAVILYDI AQCENKDVIA KYNGIPSLIN LLNLNIENVL
       850        860        870        880        890        900
VNVMNCIRVL CIGNENNQRA VREHKGLPYL IRFLSSDSDV LKAVSSAAIA EVGRDNKEIQ
       910        920        930        940        950        960
DAIAMEGAIP PLVALFKGKQ ISVQMKGAMA VESLASHNAL IQKAFLEKSL TKYLLKLLKA
       970        980        990       1000       1010       1020
FQIDVKEQGA VALWALAGQT LKQQKYMAEQ IGYSFIINML LSPSAKMQYV GGEAVIALSK
      1030       1040       1050       1060       1070       1080
DSRMHQNQIC EGNGIAPLVR LLRISTIAEG TLLSVIRAVG SICIGVAHTS NPVSQQLVVD
      1090       1100       1110       1120       1130       1140
ENAFPVLIQL LRNHPSPNIK VEVAFSLACI VLGNDVLQKD LHENEGFEYA DVLYLLHSTE
      1150       1160       1170       1180       1190       1200
KDICLRAGYA LTLFAFNNRF QQYLILESGI MTISIFERFL ESTVETEKAM AAFQIVVLAK
      1210       1220       1230       1240       1250       1260
VIRDMDHITL SARGVTILVD SLYSVQTSTI VLTGNLIASL AHSRAGIPEA FTTLGTIQRL
      1270       1280       1290       1300       1310       1320
CYHLYSGIEE VRAACSSALG YLTYNANAFR ILLKECRNKP NQFIRIKNNI SRDASINPAF
      1330       1340       1350       1360       1370       1380
LKEFQMQQTL VGLPSLSLEK NGGPSIIPIF KRGKEHRRKL KPKIQPKDSL TLLPPVTNFM
      1390       1400       1410       1420       1430
GLFKATKKTK DSHNIFSFSS TITSDITNVS RPRIVCLNQL GKHVQKANPE PAEG

Isoforms

- Isoform 2 of Ankyrin and armadillo repeat-containing protein - Isoform 3 of Ankyrin and armadillo repeat-containing protein - Isoform 4 of Ankyrin and armadillo repeat-containing protein

Sequence View

        10         20         30         40         50         60
MLRLPKKGLP RFEQVQDEDT YLENLAIQRN ASAFFEKYDR SEIQELLTTA LVSWLSAKED
        70         80         90        100        110        120
VRSQVDLPCG IMSQMNNVGF STAILLTPVD PTALLDYREV HQMIRELAIG IYCLNQIPSI
       130        140        150        160        170        180
SLEANYDQSS SCQLPPAYYD TRIGQILINI DYMLKALWHG IYMPKEKRAR FSELWRAIMD
       190        200        210        220        230        240
IDPDGKPQTN KDIFSEFSSA GLTDITKDPD FNEIYDEDVN EDPTYDPNSP EETAVFMKYA
       250        260        270        280        290        300
ENIMLKLTFS TTQIQQYENV FIFETGYWLT NAIKYNQDYL DICTYQRLQQ RLYLQKKIIQ
       310        320        330        340        350        360
KHFEKKKDIR RGIGYLKLIC FLIPFLLSLK KKMKVPYLSS LLQPFSDDKV KTERELPPFI
       370        380        390        400        410        420
YGRDFKCQNF HYKENQYFHV HGGIEFDIST PSIENALEDF QKNLEKIRDC AANTFIEDSG
       430        440        450        460        470        480
YKEYYSIPVM EFHGKSYYVI YFELETFYQQ LYKTQWWGAI NEIVNNLRLK RLPLTDAQLH
       490        500        510        520        530        540
EQFKKKLGFK RAMKCKSIPF GMKSAVERGL SAVFHTFSRK TSSSTINVSD EAGYTIFHHA
       550        560        570        580        590        600
ALHNRVSIIC QLCNANFKVN QRRFVTFSQG PTPLHLAAQA CSLETTVCLL CSKADYTLSE
       610        620        630        640        650        660
KRGWMPIHFA AFYDNVCIII ALCRKDPSLL EAEATAENQC TPLLLAATSG ALDTIQYLFS
       670        680        690        700        710        720
IGANWRKTDI KGNNIIHLSV LTFHTEVLKY IIKLNIPELP VWKTLVEMLQ CESYKRRMMA
       730        740        750        760        770        780
VMSLEVICLA NDQYWRCILD AGTIPALINL LKSSKIKLQC KTVGLLSNIS THKSAVHALV
       790        800        810        820        830        840
EAGGIPSLIN LLVCDEPEVH SRCAVILYDI AQCENKDVIA KYNGIPSLIN LLNLNIENVL
       850        860        870        880        890        900
VNVMNCIRVL CIGNENNQRA VREHKGLPYL IRFLSSDSDV LKAVSSAAIA EVGRDNKEIQ
       910        920        930        940        950        960
DAIAMEGAIP PLVALFKGKQ ISVQMKGAMA VESLASHNAL IQKAFLEKSL TKYLLKLLKA
       970        980        990       1000       1010       1020
FQIDVKEQGA VALWALAGQT LKQQKYMAEQ IGYSFIINML LSPSAKMQYV GGEAVIALSK
      1030       1040       1050       1060       1070       1080
DSRMHQNQIC EGNGIAPLVR LLRISTIAEG TLLSVIRAVG SICIGVAHTS NPVSQQLVVD
      1090       1100       1110       1120       1130       1140
ENAFPVLIQL LRNHPSPNIK VEVAFSLACI VLGNDVLQKD LHENEGFEYA DVLYLLHSTE
      1150       1160       1170       1180       1190       1200
KDICLRAGYA LTLFAFNNRF QQYLILESGI MTISIFERFL ESTVETEKAM AAFQIVVLAK
      1210       1220       1230       1240       1250       1260
VIRDMDHITL SARGVTILVD SLYSVQTSTI VLTGNLIASL AHSRAGIPEA FTTLGTIQRL
      1270       1280       1290       1300       1310       1320
CYHLYSGIEE VRAACSSALG YLTYNANAFR ILLKECRNKP NQFIRIKNNI SRDASINPAF
      1330       1340       1350       1360       1370       1380
LKEFQMQQTL VGLPSLSLEK NGGPSIIPIF KRGKEHRRKL KPKIQPKDSL TLLPPVTNFM
      1390       1400       1410       1420       1430
GLFKATKKTK DSHNIFSFSS TITSDITNVS RPRIVCLNQL GKHVQKANPE PAEG         10         20         30         40         50         60
MLRLPKKGLP RFEQVQDEDT YLENLAIQRN ASAFFEKYDR SEIQELLTTA LVSWLSAKED
        70         80         90        100        110        120
VRSQVDLPCG IMSQMNNVGF STAILLTPVD PTALLDYREV HQMIRELAIG IYCLNQIPSI
       130        140        150        160        170        180
SLEANYDQSS SCQLPPAYYD TRIGQILINI DYMLKALWHG IYMPKEKRAR FSELWRAIMD
       190        200        210        220        230        240
IDPDGKPQTN KDIFSEFSSA GLTDITKDPD FNEIYDEDVN EDPTYDPNSP EETAVFMKYA
       250        260        270        280        290        300
ENIMLKLTFS TTQIQQYENV FIFETGYWLT NAIKYNQDYL DICTYQRLQQ RLYLQKKIIQ
       310        320        330        340        350        360
KHFEKKKDIR RGIGYLKLIC FLIPFLLSLK KKMKVPYLSS LLQPFSDDKV KTERELPPFI
       370        380        390        400        410        420
YGRDFKCQNF HYKENQYFHV HGGIEFDIST PSIENALEDF QKNLEKIRDC AANTFIEDSG
       430        440        450        460        470        480
YKEYYSIPVM EFHGKSYYVI YFELETFYQQ LYKTQWWGAI NEIVNNLRLK RLPLTDAQLH
       490        500        510        520        530        540
EQFKKKLGFK RAMKCKSIPF GMKSAVERGL SAVFHTFSRK TSSSTINVSD EAGYTIFHHA
       550        560        570        580        590        600
ALHNRVSIIC QLCNANFKVN QRRFVTFSQG PTPLHLAAQA CSLETTVCLL CSKADYTLSE
       610        620        630        640        650        660
KRGWMPIHFA AFYDNVCIII ALCRKDPSLL EAEATAENQC TPLLLAATSG ALDTIQYLFS
       670        680        690        700        710        720
IGANWRKTDI KGNNIIHLSV LTFHTEVLKY IIKLNIPELP VWKTLVEMLQ CESYKRRMMA
       730        740        750        760        770        780
VMSLEVICLA NDQYWRCILD AGTIPALINL LKSSKIKLQC KTVGLLSNIS THKSAVHALV
       790        800        810        820        830        840
EAGGIPSLIN LLVCDEPEVH SRCAVILYDI AQCENKDVIA KYNGIPSLIN LLNLNIENVL
       850        860        870        880        890        900
VNVMNCIRVL CIGNENNQRA VREHKGLPYL IRFLSSDSDV LKAVSSAAIA EVGRDNKEIQ
       910        920        930        940        950        960
DAIAMEGAIP PLVALFKGKQ ISVQMKGAMA VESLASHNAL IQKAFLEKSL TKYLLKLLKA
       970        980        990       1000       1010       1020
FQIDVKEQGA VALWALAGQT LKQQKYMAEQ IGYSFIINML LSPSAKMQYV GGEAVIALSK
      1030       1040       1050       1060       1070       1080
DSRMHQNQIC EGNGIAPLVR LLRISTIAEG TLLSVIRAVG SICIGVAHTS NPVSQQLVVD
      1090       1100       1110       1120       1130       1140
ENAFPVLIQL LRNHPSPNIK VEVAFSLACI VLGNDVLQKD LHENEGFEYA DVLYLLHSTE
      1150       1160       1170       1180       1190       1200
KDICLRAGYA LTLFAFNNRF QQYLILESGI MTISIFERFL ESTVETEKAM AAFQIVVLAK
      1210       1220       1230       1240       1250       1260
VIRDMDHITL SARGVTILVD SLYSVQTSTI VLTGNLIASL AHSRAGIPEA FTTLGTIQRL
      1270       1280       1290       1300       1310       1320
CYHLYSGIEE VRAACSSALG YLTYNANAFR ILLKECRNKP NQFIRIKNNI SRDASINPAF
      1330       1340       1350       1360       1370       1380
LKEFQMQQTL VGLPSLSLEK NGGPSIIPIF KRGKEHRRKL KPKIQPKDSL TLLPPVTNFM
      1390       1400       1410       1420       1430
GLFKATKKTK DSHNIFSFSS TITSDITNVS RPRIVCLNQL GKHVQKANPE PAEG         10         20         30         40         50         60
MLRLPKKGLP RFEQVQDEDT YLENLAIQRN ASAFFEKYDR SEIQELLTTA LVSWLSAKED
        70         80         90        100        110        120
VRSQVDLPCG IMSQMNNVGF STAILLTPVD PTALLDYREV HQMIRELAIG IYCLNQIPSI
       130        140        150        160        170        180
SLEANYDQSS SCQLPPAYYD TRIGQILINI DYMLKALWHG IYMPKEKRAR FSELWRAIMD
       190        200        210        220        230        240
IDPDGKPQTN KDIFSEFSSA GLTDITKDPD FNEIYDEDVN EDPTYDPNSP EETAVFMKYA
       250        260        270        280        290        300
ENIMLKLTFS TTQIQQYENV FIFETGYWLT NAIKYNQDYL DICTYQRLQQ RLYLQKKIIQ
       310        320        330        340        350        360
KHFEKKKDIR RGIGYLKLIC FLIPFLLSLK KKMKVPYLSS LLQPFSDDKV KTERELPPFI
       370        380        390        400        410        420
YGRDFKCQNF HYKENQYFHV HGGIEFDIST PSIENALEDF QKNLEKIRDC AANTFIEDSG
       430        440        450        460        470        480
YKEYYSIPVM EFHGKSYYVI YFELETFYQQ LYKTQWWGAI NEIVNNLRLK RLPLTDAQLH
       490        500        510        520        530        540
EQFKKKLGFK RAMKCKSIPF GMKSAVERGL SAVFHTFSRK TSSSTINVSD EAGYTIFHHA
       550        560        570        580        590        600
ALHNRVSIIC QLCNANFKVN QRRFVTFSQG PTPLHLAAQA CSLETTVCLL CSKADYTLSE
       610        620        630        640        650        660
KRGWMPIHFA AFYDNVCIII ALCRKDPSLL EAEATAENQC TPLLLAATSG ALDTIQYLFS
       670        680        690        700        710        720
IGANWRKTDI KGNNIIHLSV LTFHTEVLKY IIKLNIPELP VWKTLVEMLQ CESYKRRMMA
       730        740        750        760        770        780
VMSLEVICLA NDQYWRCILD AGTIPALINL LKSSKIKLQC KTVGLLSNIS THKSAVHALV
       790        800        810        820        830        840
EAGGIPSLIN LLVCDEPEVH SRCAVILYDI AQCENKDVIA KYNGIPSLIN LLNLNIENVL
       850        860        870        880        890        900
VNVMNCIRVL CIGNENNQRA VREHKGLPYL IRFLSSDSDV LKAVSSAAIA EVGRDNKEIQ
       910        920        930        940        950        960
DAIAMEGAIP PLVALFKGKQ ISVQMKGAMA VESLASHNAL IQKAFLEKSL TKYLLKLLKA
       970        980        990       1000       1010       1020
FQIDVKEQGA VALWALAGQT LKQQKYMAEQ IGYSFIINML LSPSAKMQYV GGEAVIALSK
      1030       1040       1050       1060       1070       1080
DSRMHQNQIC EGNGIAPLVR LLRISTIAEG TLLSVIRAVG SICIGVAHTS NPVSQQLVVD
      1090       1100       1110       1120       1130       1140
ENAFPVLIQL LRNHPSPNIK VEVAFSLACI VLGNDVLQKD LHENEGFEYA DVLYLLHSTE
      1150       1160       1170       1180       1190       1200
KDICLRAGYA LTLFAFNNRF QQYLILESGI MTISIFERFL ESTVETEKAM AAFQIVVLAK
      1210       1220       1230       1240       1250       1260
VIRDMDHITL SARGVTILVD SLYSVQTSTI VLTGNLIASL AHSRAGIPEA FTTLGTIQRL
      1270       1280       1290       1300       1310       1320
CYHLYSGIEE VRAACSSALG YLTYNANAFR ILLKECRNKP NQFIRIKNNI SRDASINPAF
      1330       1340       1350       1360       1370       1380
LKEFQMQQTL VGLPSLSLEK NGGPSIIPIF KRGKEHRRKL KPKIQPKDSL TLLPPVTNFM
      1390       1400       1410       1420       1430
GLFKATKKTK DSHNIFSFSS TITSDITNVS RPRIVCLNQL GKHVQKANPE PAEG

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q7Z5J8-1-unknown	MLRLPK...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q7Z5J8-1-unknown	MLRLPK...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt66939
Q7Z5J8-177-unknown	AIMDID...	177	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19658
Q7Z5J8-177-unknown	AIMDID...	177	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt145808
Q7Z5J8-237-unknown	MKYAEN...	237	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt66940
Q7Z5J8-237-unknown	MKYAEN...	237	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt102917
Q7Z5J8-333-unknown	MKVPYL...	333	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt66941
Q7Z5J8-333-unknown	MKVPYL...	333	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt102972
Q7Z5J8-333-unknown	MKVPYL...	333	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt102973

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SELWRA	176	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19658
...SELWRA	176	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129105
...EPAEG	1434	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

TopFIND

Q7Z5J8: Ankyrin and armadillo repeat-containing protein

General Information

4

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates