Q7Z6J9: tRNA-splicing endonuclease subunit Sen54

General Information

Protein names	- tRNA-splicing endonuclease subunit Sen54 - SEN54 homolog - HsSEN54 - tRNA-intron endonuclease Sen54
Gene names	TSEN54
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q7Z6J9

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEPEPEPAAV EVPAGRVLSA RELFAARSRS QKLPQRSHGP KDFLPDGSAA QAERLRRCRE
        70         80         90        100        110        120
ELWQLLAEQR VERLGSLVAA EWRPEEGFVE LKSPAGKFWQ TMGFSEQGRQ RLHPEEALYL
       130        140        150        160        170        180
LECGSIHLFH QDLPLSIQEA YQLLLTDHTV TFLQYQVFSH LKRLGYVVRR FQPSSVLSPY
       190        200        210        220        230        240
ERQLNLDASV QHLEDGDGKR KRSSSSPRSI NKKAKALDNS LQPKSLAASS PPPCSQPSQC
       250        260        270        280        290        300
PEEKPQESSP MKGPGGPFQL LGSLGPSPGP AREGVGCSWE SGRAENGVTG AGKRRWNFEQ
       310        320        330        340        350        360
ISFPNMASDS RHTLLRAPAP ELLPANVAGR ETDAESWCQK LNQRKEKLSR REREHHAEAA
       370        380        390        400        410        420
QFQEDVNADP EVQRCSSWRE YKELLQRRQV QRSQRRAPHL WGQPVTPLLS PGQASSPAVV
       430        440        450        460        470        480
LQHISVLQTT HLPDGGARLL EKSGGLEIIF DVYQADAVAT FRKNNPGKPY ARMCISGFDE
       490        500        510        520
PVPDLCSLKR LSYQSGDVPL IFALVDHGDI SFYSFRDFTL PQDVGH

Isoforms

- Isoform 2 of tRNA-splicing endonuclease subunit Sen54

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q7Z6J9-1-unknown	MEPEPE...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt89253
Q7Z6J9-1-Acetylation	MEPEPE...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q7Z6J9-1-Acetylation	MEPEPE...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q7Z6J9-1-Acetylation	MEPEPE...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q7Z6J9-1-Acetylation	MEPEPE...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt109523
Q7Z6J9-263-	SLGPSP...	263			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q7Z6J9-361-	QFQEDV...	361			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...QDVGH	526	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)