Q7Z7H5: Transmembrane emp24 domain-containing protein 4

General Information

Protein names	- Transmembrane emp24 domain-containing protein 4 - Endoplasmic reticulum stress-response protein 25 - ERS25 - GMP25iso - Putative NF-kappa-B-activating protein 156 - p24 family protein alpha-3 - p24alpha3
Gene names	TMED4
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q7Z7H5

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Transmembrane emp24 domain-containing protein 4 - Isoform 3 of Transmembrane emp24 domain-containing protein 4

Sequence View

        10         20         30         40         50         60
MAGVGAGPLR AMGRQALLLL ALCATGAQGL YFHIGETEKR CFIEEIPDET MVIGNYRTQM
        70         80         90        100        110        120
WDKQKEVFLP STPGLGMHVE VKDPDGKVVL SRQYGSEGRF TFTSHTPGDH QICLHSNSTR
       130        140        150        160        170        180
MALFAGGKLR VHLDIQVGEH ANNYPEIAAK DKLTELQLRA RQLLDQVEQI QKEQDYQRYR
       190        200        210        220
EERFRLTSES TNQRVLWWSI AQTVILILTG IWQMRHLKSF FEAKKLV         10         20         30         40         50         60
MAGVGAGPLR AMGRQALLLL ALCATGAQGL YFHIGETEKR CFIEEIPDET MVIGNYRTQM
        70         80         90        100        110        120
WDKQKEVFLP STPGLGMHVE VKDPDGKVVL SRQYGSEGRF TFTSHTPGDH QICLHSNSTR
       130        140        150        160        170        180
MALFAGGKLR VHLDIQVGEH ANNYPEIAAK DKLTELQLRA RQLLDQVEQI QKEQDYQRYR
       190        200        210        220
EERFRLTSES TNQRVLWWSI AQTVILILTG IWQMRHLKSF FEAKKLV

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q7Z7H5-1-unknown	MAGVGA...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt92469
Q7Z7H5-1-unknown	MAGVGA...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt92470
Q7Z7H5-30-	LYFHIG...	30		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q7Z7H5-30-	LYFHIG...	30		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q7Z7H5-30-	LYFHIG...	30		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q7Z7H5-30-	LYFHIG...	30		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q7Z7H5-30-	LYFHIG...	30		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q7Z7H5-30-	LYFHIG...	30		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
Q7Z7H5-30-	LYFHIG...	30		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q7Z7H5-30-unknown	LYFHIG...	30	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q7Z7H5-30-unknown	LYFHIG...	30	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt114769
Q7Z7H5-30-unknown	LYFHIG...	30	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt114770

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...AKKLV	227	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...AKKLV	227	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt88087

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)