Q810A7: ATP-dependent RNA helicase DDX42
Protein names | - ATP-dependent RNA helicase DDX42 - 3.6.4.13 - DEAD box protein 42 |
---|---|
Gene names | Ddx42 |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q810A7 |
3
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MNWNKGGPGT KRGFGFGGFA ISAGKKEEAK LPQQSHSAFG AASSSSGFGK SAPPQLPSFY
70 80 90 100 110 120
KIGSKRANFD EENAYFEDEE EDSSNVDLPY IPAENSPTRQ QFHSKPADSD SDDDPLEAFM
130 140 150 160 170 180
AEVEDQAARD MKRLEEKDKE RKNVKGIRDD IEEEDDQEAY FRYMAENPTA GVVQEEEEDN
190 200 210 220 230 240
LEYDSDGNPI APSKKIIDPL PPIDHSEIDY PPFEKNFYNE HEEITNLTPQ QLIDLRHKLN
250 260 270 280 290 300
LRVSGAAPPR PGSSFAHFGF DEQLMHQIRK SEYTQPTPIQ CQGVPVALSG RDMIGIAKTG
310 320 330 340 350 360
SGKTAAFIWP MLIHIMDQKE LEPGDGPIAV IVCPTRELCQ QIHAECKRFG KAYNLRSVAV
370 380 390 400 410 420
YGGGSMWEQA KALQEGAEIV VCTPGRLIDH VKKKATNLQR VSYLVFDEAD RMFDMGFEYQ
430 440 450 460 470 480
VRSIASHVRP DRQTLLFSAT FRKKIEKLAR DILIDPIRVV QGDIGEANED VTQIVEILHS
490 500 510 520 530 540
GPSKWNWLTR RLVEFTSSGS VLLFVTKKAN AEELASNLKQ EGHNLGLLHG DMDQSERNKV
550 560 570 580 590 600
ISDFKKKDIP VLVATDVAAR GLDIPSIKTV INYDVARDID THTHRIGRTG RAGEKGVAYT
610 620 630 640 650 660
LLTPKDSNFA GDLVRNLEGA NQHVSKELLD LAMQNAWFRK SRFKGGKGKK LNIGGGGLGY
670 680 690 700 710 720
RERPGLGSEN SDRGNNNNVM SNYEAYKPST GAMGDRLTAM KAAFQSQYKS HFVAASLSNQ
730 740 750 760 770 780
KAGTSSAGAS GWTSAGSLNS VPTNSAQQGH NSPDNPMTSS TKNIPGFNNS GNISSAPVTY
790 800 810 820 830 840
PSIGAQGVNN TASGNNSREG IGGGNGKRER YTENRGGSRH SHGDGGNRHG DGGRHGDGYR
850 860 870 880 890 900
YPESGSRHTD GHRHGETRHG GSAGRHGESR GANDGRNGES RKEGFNRENK MDPKVDSSRM
910 920
DKVDSKTDKT PDGFAVPEPP KRKKSRWDS
Isoforms
- Isoform 2 of ATP-dependent RNA helicase DDX42Sequence View
10 20 30 40 50 60
MNWNKGGPGT KRGFGFGGFA ISAGKKEEAK LPQQSHSAFG AASSSSGFGK SAPPQLPSFY
70 80 90 100 110 120
KIGSKRANFD EENAYFEDEE EDSSNVDLPY IPAENSPTRQ QFHSKPADSD SDDDPLEAFM
130 140 150 160 170 180
AEVEDQAARD MKRLEEKDKE RKNVKGIRDD IEEEDDQEAY FRYMAENPTA GVVQEEEEDN
190 200 210 220 230 240
LEYDSDGNPI APSKKIIDPL PPIDHSEIDY PPFEKNFYNE HEEITNLTPQ QLIDLRHKLN
250 260 270 280 290 300
LRVSGAAPPR PGSSFAHFGF DEQLMHQIRK SEYTQPTPIQ CQGVPVALSG RDMIGIAKTG
310 320 330 340 350 360
SGKTAAFIWP MLIHIMDQKE LEPGDGPIAV IVCPTRELCQ QIHAECKRFG KAYNLRSVAV
370 380 390 400 410 420
YGGGSMWEQA KALQEGAEIV VCTPGRLIDH VKKKATNLQR VSYLVFDEAD RMFDMGFEYQ
430 440 450 460 470 480
VRSIASHVRP DRQTLLFSAT FRKKIEKLAR DILIDPIRVV QGDIGEANED VTQIVEILHS
490 500 510 520 530 540
GPSKWNWLTR RLVEFTSSGS VLLFVTKKAN AEELASNLKQ EGHNLGLLHG DMDQSERNKV
550 560 570 580 590 600
ISDFKKKDIP VLVATDVAAR GLDIPSIKTV INYDVARDID THTHRIGRTG RAGEKGVAYT
610 620 630 640 650 660
LLTPKDSNFA GDLVRNLEGA NQHVSKELLD LAMQNAWFRK SRFKGGKGKK LNIGGGGLGY
670 680 690 700 710 720
RERPGLGSEN SDRGNNNNVM SNYEAYKPST GAMGDRLTAM KAAFQSQYKS HFVAASLSNQ
730 740 750 760 770 780
KAGTSSAGAS GWTSAGSLNS VPTNSAQQGH NSPDNPMTSS TKNIPGFNNS GNISSAPVTY
790 800 810 820 830 840
PSIGAQGVNN TASGNNSREG IGGGNGKRER YTENRGGSRH SHGDGGNRHG DGGRHGDGYR
850 860 870 880 890 900
YPESGSRHTD GHRHGETRHG GSAGRHGESR GANDGRNGES RKEGFNRENK MDPKVDSSRM
910 920
DKVDSKTDKT PDGFAVPEPP KRKKSRWDS
Protein Neighborhood
Domains & Features
3 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q810A7-1-Acetylation | MNWNKG... | 1 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
Q810A7-120-unknown | MAEVED... | 120 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt72546 | |||
Q810A7-120-unknown | MAEVED... | 120 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32620 | |||
Q810A7-121-unknown | AEVEDQ... | 121 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32621 | |||
Q810A7-121-unknown | AEVEDQ... | 121 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt197257 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...PLEAFM | 119 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32620 | |||
...LEAFMA | 120 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32621 | |||
...SRWDS | 929 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...SRWDS | 929 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt68164 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAC_MOUSE | 119 | EAFM.|.MAEV | inferred from experiment | unknown | MEROPS | Bird PI | Kaiserman D et al.:Structure of granzyme C reveals... (S01.137) | 19299505, |
GRAC_MOUSE | 120 | AFMA.|.AEVE | inferred from experiment | unknown | MEROPS | Bird PI | Kaiserman D et al.:Structure of granzyme C reveals... (S01.137) | 19299505, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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