Q86SX6: Glutaredoxin-related protein 5, mitochondrial

General Information

Protein names	- Glutaredoxin-related protein 5, mitochondrial - Monothiol glutaredoxin-5
Gene names	GLRX5
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q86SX6

5 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSGSLGRAAA ALLRWGRGAG GGGLWGPGVR AAGSGAGGGG SAEQLDALVK KDKVVVFLKG
        70         80         90        100        110        120
TPEQPQCGFS NAVVQILRLH GVRDYAAYNV LDDPELRQGI KDYSNWPTIP QVYLNGEFVG
       130        140        150
GCDILLQMHQ NGDLVEELKK LGIHSALLDE KKDQDSK

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q86SX6-18-	GAGGGG...	18		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q86SX6-32-	AGSGAG...	32		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q86SX6-32-	AGSGAG...	32		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q86SX6-32-	AGSGAG...	32		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
Q86SX6-32-	AGSGAG...	32		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q86SX6-32-	AGSGAG...	32		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q86SX6-32-	AGSGAG...	32		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q86SX6-32-	AGSGAG...	32		Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
Q86SX6-32-unknown	AGSGAG...	32	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q86SX6-32-unknown	AGSGAG...	32		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q86SX6-32-unknown	AGSGAG...	32		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q86SX6-33-	GSGAGG...	33		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q86SX6-33-	GSGAGG...	33		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q86SX6-33-	GSGAGG...	33		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q86SX6-33-	GSGAGG...	33		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
Q86SX6-33-	GSGAGG...	33		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q86SX6-33-	GSGAGG...	33		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q86SX6-33-	GSGAGG...	33		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q86SX6-33-	GSGAGG...	33		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q86SX6-33-	GSGAGG...	33		Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
Q86SX6-33-unknown	GSGAGG...	33		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q86SX6-33-unknown	GSGAGG...	33		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...DQDSK	157	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)