Q86UR5: Regulating synaptic membrane exocytosis protein 1

General Information

Protein names	- Regulating synaptic membrane exocytosis protein 1 - Rab-3-interacting molecule 1 - RIM 1 - Rab-3-interacting protein 2
Gene names	RIMS1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q86UR5

6 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Regulating synaptic membrane exocytosis protein 1 - Isoform 3 of Regulating synaptic membrane exocytosis protein 1 - Isoform 4 of Regulating synaptic membrane exocytosis protein 1 - Isoform 5 of Regulating synaptic membrane exocytosis protein 1 - Isoform 6 of Regulating synaptic membrane exocytosis protein 1 - Isoform 7 of Regulating synaptic membrane exocytosis protein 1 - Isoform 8 of Regulating synaptic membrane exocytosis protein 1 - Isoform 9 of Regulating synaptic membrane exocytosis protein 1 - Isoform 10 of Regulating synaptic membrane exocytosis protein 1 - Isoform 11 of Regulating synaptic membrane exocytosis protein 1 - Isoform 12 of Regulating synaptic membrane exocytosis protein 1 - Isoform 13 of Regulating synaptic membrane exocytosis protein 1

Sequence View

        10         20         30         40         50         60
MSSAVGPRGP RPPTVPPPMQ ELPDLSHLTE EERNIIMAVM DRQKEEEEKE EAMLKCVVRD
        70         80         90        100        110        120
MAKPAACKTP RNAENQPHQP SPRLHQQFES YKEQVRKIGE EARRYQGEHK DDAPTCGICH
       130        140        150        160        170        180
KTKFADGCGH LCSYCRTKFC ARCGGRVSLR SNNEDKVVMW VCNLCRKQQE ILTKSGAWFF
       190        200        210        220        230        240
GSGPQQTSQD GTLSDTATGA GSEVPREKKA RLQERSRSQT PLSTAAASSQ DAAPPSAPPD
       250        260        270        280        290        300
RSKGAEPSQQ ALGPEQKQAS SRSRSEPPRE RKKTPGLSEQ NGKGALKSER KRVPKTSAQP
       310        320        330        340        350        360
VEGAVEERER KERRESRRLE KGRSQDYPDT PEKRDEGKAA DEEKQRKEED YQTRYRSDPN
       370        380        390        400        410        420
LARYPVKPPP EEQQMRMHAR VSRARHERRH SDVALPRTEA GAALPEGKAG KRAPAAARAS
       430        440        450        460        470        480
PPDSPRAYSA ERTAETRAPG AKQLTNHSPP APRHGPVPAE APELKAQEPL RKQSRLDPSS
       490        500        510        520        530        540
AVLMRKAKRE KVETMLRNDS LSSDQSESVR PSPPKPHRSK RGGKKRQMSV SSSEEEGVST
       550        560        570        580        590        600
PEYTSCEDVE LESESVSEKG DLDYYWLDPA TWHSRETSPI SSHPVTWQPS KEGDRLIGRV
       610        620        630        640        650        660
ILNKRTTMPK DSGALLGLKV VGGKMTDLGR LGAFITKVKK GSLADVVGHL RAGDEVLEWN
       670        680        690        700        710        720
GKPLPGATNE EVYNIILESK SEPQVEIIVS RPIGDIPRIP ESSHPPLESS SSSFESQKME
       730        740        750        760        770        780
RPSISVISPT SPGALKDAPQ VLPGQLSVKL WYDKVGHQLI VNVLQATDLP ARVDGRPRNP
       790        800        810        820        830        840
YVKMYFLPDR SDKSKRRTKT VKKILEPKWN QTFVYSHVHR RDFRERMLEI TVWDQPRVQE
       850        860        870        880        890        900
EESEFLGEIL IELETALLDD EPHWYKLQTH DESSLPLPQP SPFMPRRHIH GESSSKKLQR
       910        920        930        940        950        960
SQRISDSDIS DYEVDDGIGV VPPVGYRSSA RESKSTTLTV PEQQRTTHHR SRSVSPHRGN
       970        980        990       1000       1010       1020
DQGKPRSRLP NVPLQRSLDE IHPTRRSRSP TRHHDASRSP VDHRTRDVDS QYLSEQDSEL
      1030       1040       1050       1060       1070       1080
LMLPRAKRGR SAECLHTTRH LVRHYKTLPP KMPLLQSSSH WNIYSSILPA HTKTKSVTRQ
      1090       1100       1110       1120       1130       1140
DISLHHECFN STVLRFTDEI LVSELQPFLD RARSASTNCL RPDTSLHSPE RERGRWSPSL
      1150       1160       1170       1180       1190       1200
DRRRPPSPRI QIQHASPEND RHSRKSERSS IQKQTRKGTA SDAERVLPTC LSRRGHAAPR
      1210       1220       1230       1240       1250       1260
ATDQPVIRGK HPARSRSSEH SSIRTLCSMH HLVPGGSAPP SPLLTRMHRQ RSPTQSPPAD
      1270       1280       1290       1300       1310       1320
TSFSSRRGRQ LPQVPVRSGS IEQASLVVEE RTRQMKMKVH RFKQTTGSGS SQELDREQYS
      1330       1340       1350       1360       1370       1380
KYNIHKDQYR SCDNVSAKSS DSDVSDVSAI SRTSSASRLS STSFMSEQSE RPRGRISSFT
      1390       1400       1410       1420       1430       1440
PKMQGRRMGT SGRSIMKSTS VSGEMYTLEH NDGSQSDTAV GTVGAGGKKR RSSLSAKVVA
      1450       1460       1470       1480       1490       1500
IVSRRSRSTS QLSQTESGHK KLKSTIQRST ETGMAAEMRK MVRQPSREST DGSINSYSSE
      1510       1520       1530       1540       1550       1560
GNLIFPGVRL GADSQFSDFL DGLGPAQLVG RQTLATPAMG DIQIGMEDKK GQLEVEVIRA
      1570       1580       1590       1600       1610       1620
RSLTQKPGSK STPAPYVKVY LLENGACIAK KKTRIARKTL DPLYQQSLVF DESPQGKVLQ
      1630       1640       1650       1660       1670       1680
VIVWGDYGRM DHKCFMGVAQ ILLEELDLSS MVIGWYKLFP PSSLVDPTLT PLTRRASQSS
      1690
LESSTGPPCI RS         10         20         30         40         50         60
MSSAVGPRGP RPPTVPPPMQ ELPDLSHLTE EERNIIMAVM DRQKEEEEKE EAMLKCVVRD
        70         80         90        100        110        120
MAKPAACKTP RNAENQPHQP SPRLHQQFES YKEQVRKIGE EARRYQGEHK DDAPTCGICH
       130        140        150        160        170        180
KTKFADGCGH LCSYCRTKFC ARCGGRVSLR SNNEDKVVMW VCNLCRKQQE ILTKSGAWFF
       190        200        210        220        230        240
GSGPQQTSQD GTLSDTATGA GSEVPREKKA RLQERSRSQT PLSTAAASSQ DAAPPSAPPD
       250        260        270        280        290        300
RSKGAEPSQQ ALGPEQKQAS SRSRSEPPRE RKKTPGLSEQ NGKGALKSER KRVPKTSAQP
       310        320        330        340        350        360
VEGAVEERER KERRESRRLE KGRSQDYPDT PEKRDEGKAA DEEKQRKEED YQTRYRSDPN
       370        380        390        400        410        420
LARYPVKPPP EEQQMRMHAR VSRARHERRH SDVALPRTEA GAALPEGKAG KRAPAAARAS
       430        440        450        460        470        480
PPDSPRAYSA ERTAETRAPG AKQLTNHSPP APRHGPVPAE APELKAQEPL RKQSRLDPSS
       490        500        510        520        530        540
AVLMRKAKRE KVETMLRNDS LSSDQSESVR PSPPKPHRSK RGGKKRQMSV SSSEEEGVST
       550        560        570        580        590        600
PEYTSCEDVE LESESVSEKG DLDYYWLDPA TWHSRETSPI SSHPVTWQPS KEGDRLIGRV
       610        620        630        640        650        660
ILNKRTTMPK DSGALLGLKV VGGKMTDLGR LGAFITKVKK GSLADVVGHL RAGDEVLEWN
       670        680        690        700        710        720
GKPLPGATNE EVYNIILESK SEPQVEIIVS RPIGDIPRIP ESSHPPLESS SSSFESQKME
       730        740        750        760        770        780
RPSISVISPT SPGALKDAPQ VLPGQLSVKL WYDKVGHQLI VNVLQATDLP ARVDGRPRNP
       790        800        810        820        830        840
YVKMYFLPDR SDKSKRRTKT VKKILEPKWN QTFVYSHVHR RDFRERMLEI TVWDQPRVQE
       850        860        870        880        890        900
EESEFLGEIL IELETALLDD EPHWYKLQTH DESSLPLPQP SPFMPRRHIH GESSSKKLQR
       910        920        930        940        950        960
SQRISDSDIS DYEVDDGIGV VPPVGYRSSA RESKSTTLTV PEQQRTTHHR SRSVSPHRGN
       970        980        990       1000       1010       1020
DQGKPRSRLP NVPLQRSLDE IHPTRRSRSP TRHHDASRSP VDHRTRDVDS QYLSEQDSEL
      1030       1040       1050       1060       1070       1080
LMLPRAKRGR SAECLHTTRH LVRHYKTLPP KMPLLQSSSH WNIYSSILPA HTKTKSVTRQ
      1090       1100       1110       1120       1130       1140
DISLHHECFN STVLRFTDEI LVSELQPFLD RARSASTNCL RPDTSLHSPE RERGRWSPSL
      1150       1160       1170       1180       1190       1200
DRRRPPSPRI QIQHASPEND RHSRKSERSS IQKQTRKGTA SDAERVLPTC LSRRGHAAPR
      1210       1220       1230       1240       1250       1260
ATDQPVIRGK HPARSRSSEH SSIRTLCSMH HLVPGGSAPP SPLLTRMHRQ RSPTQSPPAD
      1270       1280       1290       1300       1310       1320
TSFSSRRGRQ LPQVPVRSGS IEQASLVVEE RTRQMKMKVH RFKQTTGSGS SQELDREQYS
      1330       1340       1350       1360       1370       1380
KYNIHKDQYR SCDNVSAKSS DSDVSDVSAI SRTSSASRLS STSFMSEQSE RPRGRISSFT
      1390       1400       1410       1420       1430       1440
PKMQGRRMGT SGRSIMKSTS VSGEMYTLEH NDGSQSDTAV GTVGAGGKKR RSSLSAKVVA
      1450       1460       1470       1480       1490       1500
IVSRRSRSTS QLSQTESGHK KLKSTIQRST ETGMAAEMRK MVRQPSREST DGSINSYSSE
      1510       1520       1530       1540       1550       1560
GNLIFPGVRL GADSQFSDFL DGLGPAQLVG RQTLATPAMG DIQIGMEDKK GQLEVEVIRA
      1570       1580       1590       1600       1610       1620
RSLTQKPGSK STPAPYVKVY LLENGACIAK KKTRIARKTL DPLYQQSLVF DESPQGKVLQ
      1630       1640       1650       1660       1670       1680
VIVWGDYGRM DHKCFMGVAQ ILLEELDLSS MVIGWYKLFP PSSLVDPTLT PLTRRASQSS
      1690
LESSTGPPCI RS         10         20         30         40         50         60
MSSAVGPRGP RPPTVPPPMQ ELPDLSHLTE EERNIIMAVM DRQKEEEEKE EAMLKCVVRD
        70         80         90        100        110        120
MAKPAACKTP RNAENQPHQP SPRLHQQFES YKEQVRKIGE EARRYQGEHK DDAPTCGICH
       130        140        150        160        170        180
KTKFADGCGH LCSYCRTKFC ARCGGRVSLR SNNEDKVVMW VCNLCRKQQE ILTKSGAWFF
       190        200        210        220        230        240
GSGPQQTSQD GTLSDTATGA GSEVPREKKA RLQERSRSQT PLSTAAASSQ DAAPPSAPPD
       250        260        270        280        290        300
RSKGAEPSQQ ALGPEQKQAS SRSRSEPPRE RKKTPGLSEQ NGKGALKSER KRVPKTSAQP
       310        320        330        340        350        360
VEGAVEERER KERRESRRLE KGRSQDYPDT PEKRDEGKAA DEEKQRKEED YQTRYRSDPN
       370        380        390        400        410        420
LARYPVKPPP EEQQMRMHAR VSRARHERRH SDVALPRTEA GAALPEGKAG KRAPAAARAS
       430        440        450        460        470        480
PPDSPRAYSA ERTAETRAPG AKQLTNHSPP APRHGPVPAE APELKAQEPL RKQSRLDPSS
       490        500        510        520        530        540
AVLMRKAKRE KVETMLRNDS LSSDQSESVR PSPPKPHRSK RGGKKRQMSV SSSEEEGVST
       550        560        570        580        590        600
PEYTSCEDVE LESESVSEKG DLDYYWLDPA TWHSRETSPI SSHPVTWQPS KEGDRLIGRV
       610        620        630        640        650        660
ILNKRTTMPK DSGALLGLKV VGGKMTDLGR LGAFITKVKK GSLADVVGHL RAGDEVLEWN
       670        680        690        700        710        720
GKPLPGATNE EVYNIILESK SEPQVEIIVS RPIGDIPRIP ESSHPPLESS SSSFESQKME
       730        740        750        760        770        780
RPSISVISPT SPGALKDAPQ VLPGQLSVKL WYDKVGHQLI VNVLQATDLP ARVDGRPRNP
       790        800        810        820        830        840
YVKMYFLPDR SDKSKRRTKT VKKILEPKWN QTFVYSHVHR RDFRERMLEI TVWDQPRVQE
       850        860        870        880        890        900
EESEFLGEIL IELETALLDD EPHWYKLQTH DESSLPLPQP SPFMPRRHIH GESSSKKLQR
       910        920        930        940        950        960
SQRISDSDIS DYEVDDGIGV VPPVGYRSSA RESKSTTLTV PEQQRTTHHR SRSVSPHRGN
       970        980        990       1000       1010       1020
DQGKPRSRLP NVPLQRSLDE IHPTRRSRSP TRHHDASRSP VDHRTRDVDS QYLSEQDSEL
      1030       1040       1050       1060       1070       1080
LMLPRAKRGR SAECLHTTRH LVRHYKTLPP KMPLLQSSSH WNIYSSILPA HTKTKSVTRQ
      1090       1100       1110       1120       1130       1140
DISLHHECFN STVLRFTDEI LVSELQPFLD RARSASTNCL RPDTSLHSPE RERGRWSPSL
      1150       1160       1170       1180       1190       1200
DRRRPPSPRI QIQHASPEND RHSRKSERSS IQKQTRKGTA SDAERVLPTC LSRRGHAAPR
      1210       1220       1230       1240       1250       1260
ATDQPVIRGK HPARSRSSEH SSIRTLCSMH HLVPGGSAPP SPLLTRMHRQ RSPTQSPPAD
      1270       1280       1290       1300       1310       1320
TSFSSRRGRQ LPQVPVRSGS IEQASLVVEE RTRQMKMKVH RFKQTTGSGS SQELDREQYS
      1330       1340       1350       1360       1370       1380
KYNIHKDQYR SCDNVSAKSS DSDVSDVSAI SRTSSASRLS STSFMSEQSE RPRGRISSFT
      1390       1400       1410       1420       1430       1440
PKMQGRRMGT SGRSIMKSTS VSGEMYTLEH NDGSQSDTAV GTVGAGGKKR RSSLSAKVVA
      1450       1460       1470       1480       1490       1500
IVSRRSRSTS QLSQTESGHK KLKSTIQRST ETGMAAEMRK MVRQPSREST DGSINSYSSE
      1510       1520       1530       1540       1550       1560
GNLIFPGVRL GADSQFSDFL DGLGPAQLVG RQTLATPAMG DIQIGMEDKK GQLEVEVIRA
      1570       1580       1590       1600       1610       1620
RSLTQKPGSK STPAPYVKVY LLENGACIAK KKTRIARKTL DPLYQQSLVF DESPQGKVLQ
      1630       1640       1650       1660       1670       1680
VIVWGDYGRM DHKCFMGVAQ ILLEELDLSS MVIGWYKLFP PSSLVDPTLT PLTRRASQSS
      1690
LESSTGPPCI RS         10         20         30         40         50         60
MSSAVGPRGP RPPTVPPPMQ ELPDLSHLTE EERNIIMAVM DRQKEEEEKE EAMLKCVVRD
        70         80         90        100        110        120
MAKPAACKTP RNAENQPHQP SPRLHQQFES YKEQVRKIGE EARRYQGEHK DDAPTCGICH
       130        140        150        160        170        180
KTKFADGCGH LCSYCRTKFC ARCGGRVSLR SNNEDKVVMW VCNLCRKQQE ILTKSGAWFF
       190        200        210        220        230        240
GSGPQQTSQD GTLSDTATGA GSEVPREKKA RLQERSRSQT PLSTAAASSQ DAAPPSAPPD
       250        260        270        280        290        300
RSKGAEPSQQ ALGPEQKQAS SRSRSEPPRE RKKTPGLSEQ NGKGALKSER KRVPKTSAQP
       310        320        330        340        350        360
VEGAVEERER KERRESRRLE KGRSQDYPDT PEKRDEGKAA DEEKQRKEED YQTRYRSDPN
       370        380        390        400        410        420
LARYPVKPPP EEQQMRMHAR VSRARHERRH SDVALPRTEA GAALPEGKAG KRAPAAARAS
       430        440        450        460        470        480
PPDSPRAYSA ERTAETRAPG AKQLTNHSPP APRHGPVPAE APELKAQEPL RKQSRLDPSS
       490        500        510        520        530        540
AVLMRKAKRE KVETMLRNDS LSSDQSESVR PSPPKPHRSK RGGKKRQMSV SSSEEEGVST
       550        560        570        580        590        600
PEYTSCEDVE LESESVSEKG DLDYYWLDPA TWHSRETSPI SSHPVTWQPS KEGDRLIGRV
       610        620        630        640        650        660
ILNKRTTMPK DSGALLGLKV VGGKMTDLGR LGAFITKVKK GSLADVVGHL RAGDEVLEWN
       670        680        690        700        710        720
GKPLPGATNE EVYNIILESK SEPQVEIIVS RPIGDIPRIP ESSHPPLESS SSSFESQKME
       730        740        750        760        770        780
RPSISVISPT SPGALKDAPQ VLPGQLSVKL WYDKVGHQLI VNVLQATDLP ARVDGRPRNP
       790        800        810        820        830        840
YVKMYFLPDR SDKSKRRTKT VKKILEPKWN QTFVYSHVHR RDFRERMLEI TVWDQPRVQE
       850        860        870        880        890        900
EESEFLGEIL IELETALLDD EPHWYKLQTH DESSLPLPQP SPFMPRRHIH GESSSKKLQR
       910        920        930        940        950        960
SQRISDSDIS DYEVDDGIGV VPPVGYRSSA RESKSTTLTV PEQQRTTHHR SRSVSPHRGN
       970        980        990       1000       1010       1020
DQGKPRSRLP NVPLQRSLDE IHPTRRSRSP TRHHDASRSP VDHRTRDVDS QYLSEQDSEL
      1030       1040       1050       1060       1070       1080
LMLPRAKRGR SAECLHTTRH LVRHYKTLPP KMPLLQSSSH WNIYSSILPA HTKTKSVTRQ
      1090       1100       1110       1120       1130       1140
DISLHHECFN STVLRFTDEI LVSELQPFLD RARSASTNCL RPDTSLHSPE RERGRWSPSL
      1150       1160       1170       1180       1190       1200
DRRRPPSPRI QIQHASPEND RHSRKSERSS IQKQTRKGTA SDAERVLPTC LSRRGHAAPR
      1210       1220       1230       1240       1250       1260
ATDQPVIRGK HPARSRSSEH SSIRTLCSMH HLVPGGSAPP SPLLTRMHRQ RSPTQSPPAD
      1270       1280       1290       1300       1310       1320
TSFSSRRGRQ LPQVPVRSGS IEQASLVVEE RTRQMKMKVH RFKQTTGSGS SQELDREQYS
      1330       1340       1350       1360       1370       1380
KYNIHKDQYR SCDNVSAKSS DSDVSDVSAI SRTSSASRLS STSFMSEQSE RPRGRISSFT
      1390       1400       1410       1420       1430       1440
PKMQGRRMGT SGRSIMKSTS VSGEMYTLEH NDGSQSDTAV GTVGAGGKKR RSSLSAKVVA
      1450       1460       1470       1480       1490       1500
IVSRRSRSTS QLSQTESGHK KLKSTIQRST ETGMAAEMRK MVRQPSREST DGSINSYSSE
      1510       1520       1530       1540       1550       1560
GNLIFPGVRL GADSQFSDFL DGLGPAQLVG RQTLATPAMG DIQIGMEDKK GQLEVEVIRA
      1570       1580       1590       1600       1610       1620
RSLTQKPGSK STPAPYVKVY LLENGACIAK KKTRIARKTL DPLYQQSLVF DESPQGKVLQ
      1630       1640       1650       1660       1670       1680
VIVWGDYGRM DHKCFMGVAQ ILLEELDLSS MVIGWYKLFP PSSLVDPTLT PLTRRASQSS
      1690
LESSTGPPCI RS         10         20         30         40         50         60
MSSAVGPRGP RPPTVPPPMQ ELPDLSHLTE EERNIIMAVM DRQKEEEEKE EAMLKCVVRD
        70         80         90        100        110        120
MAKPAACKTP RNAENQPHQP SPRLHQQFES YKEQVRKIGE EARRYQGEHK DDAPTCGICH
       130        140        150        160        170        180
KTKFADGCGH LCSYCRTKFC ARCGGRVSLR SNNEDKVVMW VCNLCRKQQE ILTKSGAWFF
       190        200        210        220        230        240
GSGPQQTSQD GTLSDTATGA GSEVPREKKA RLQERSRSQT PLSTAAASSQ DAAPPSAPPD
       250        260        270        280        290        300
RSKGAEPSQQ ALGPEQKQAS SRSRSEPPRE RKKTPGLSEQ NGKGALKSER KRVPKTSAQP
       310        320        330        340        350        360
VEGAVEERER KERRESRRLE KGRSQDYPDT PEKRDEGKAA DEEKQRKEED YQTRYRSDPN
       370        380        390        400        410        420
LARYPVKPPP EEQQMRMHAR VSRARHERRH SDVALPRTEA GAALPEGKAG KRAPAAARAS
       430        440        450        460        470        480
PPDSPRAYSA ERTAETRAPG AKQLTNHSPP APRHGPVPAE APELKAQEPL RKQSRLDPSS
       490        500        510        520        530        540
AVLMRKAKRE KVETMLRNDS LSSDQSESVR PSPPKPHRSK RGGKKRQMSV SSSEEEGVST
       550        560        570        580        590        600
PEYTSCEDVE LESESVSEKG DLDYYWLDPA TWHSRETSPI SSHPVTWQPS KEGDRLIGRV
       610        620        630        640        650        660
ILNKRTTMPK DSGALLGLKV VGGKMTDLGR LGAFITKVKK GSLADVVGHL RAGDEVLEWN
       670        680        690        700        710        720
GKPLPGATNE EVYNIILESK SEPQVEIIVS RPIGDIPRIP ESSHPPLESS SSSFESQKME
       730        740        750        760        770        780
RPSISVISPT SPGALKDAPQ VLPGQLSVKL WYDKVGHQLI VNVLQATDLP ARVDGRPRNP
       790        800        810        820        830        840
YVKMYFLPDR SDKSKRRTKT VKKILEPKWN QTFVYSHVHR RDFRERMLEI TVWDQPRVQE
       850        860        870        880        890        900
EESEFLGEIL IELETALLDD EPHWYKLQTH DESSLPLPQP SPFMPRRHIH GESSSKKLQR
       910        920        930        940        950        960
SQRISDSDIS DYEVDDGIGV VPPVGYRSSA RESKSTTLTV PEQQRTTHHR SRSVSPHRGN
       970        980        990       1000       1010       1020
DQGKPRSRLP NVPLQRSLDE IHPTRRSRSP TRHHDASRSP VDHRTRDVDS QYLSEQDSEL
      1030       1040       1050       1060       1070       1080
LMLPRAKRGR SAECLHTTRH LVRHYKTLPP KMPLLQSSSH WNIYSSILPA HTKTKSVTRQ
      1090       1100       1110       1120       1130       1140
DISLHHECFN STVLRFTDEI LVSELQPFLD RARSASTNCL RPDTSLHSPE RERGRWSPSL
      1150       1160       1170       1180       1190       1200
DRRRPPSPRI QIQHASPEND RHSRKSERSS IQKQTRKGTA SDAERVLPTC LSRRGHAAPR
      1210       1220       1230       1240       1250       1260
ATDQPVIRGK HPARSRSSEH SSIRTLCSMH HLVPGGSAPP SPLLTRMHRQ RSPTQSPPAD
      1270       1280       1290       1300       1310       1320
TSFSSRRGRQ LPQVPVRSGS IEQASLVVEE RTRQMKMKVH RFKQTTGSGS SQELDREQYS
      1330       1340       1350       1360       1370       1380
KYNIHKDQYR SCDNVSAKSS DSDVSDVSAI SRTSSASRLS STSFMSEQSE RPRGRISSFT
      1390       1400       1410       1420       1430       1440
PKMQGRRMGT SGRSIMKSTS VSGEMYTLEH NDGSQSDTAV GTVGAGGKKR RSSLSAKVVA
      1450       1460       1470       1480       1490       1500
IVSRRSRSTS QLSQTESGHK KLKSTIQRST ETGMAAEMRK MVRQPSREST DGSINSYSSE
      1510       1520       1530       1540       1550       1560
GNLIFPGVRL GADSQFSDFL DGLGPAQLVG RQTLATPAMG DIQIGMEDKK GQLEVEVIRA
      1570       1580       1590       1600       1610       1620
RSLTQKPGSK STPAPYVKVY LLENGACIAK KKTRIARKTL DPLYQQSLVF DESPQGKVLQ
      1630       1640       1650       1660       1670       1680
VIVWGDYGRM DHKCFMGVAQ ILLEELDLSS MVIGWYKLFP PSSLVDPTLT PLTRRASQSS
      1690
LESSTGPPCI RS         10         20         30         40         50         60
MSSAVGPRGP RPPTVPPPMQ ELPDLSHLTE EERNIIMAVM DRQKEEEEKE EAMLKCVVRD
        70         80         90        100        110        120
MAKPAACKTP RNAENQPHQP SPRLHQQFES YKEQVRKIGE EARRYQGEHK DDAPTCGICH
       130        140        150        160        170        180
KTKFADGCGH LCSYCRTKFC ARCGGRVSLR SNNEDKVVMW VCNLCRKQQE ILTKSGAWFF
       190        200        210        220        230        240
GSGPQQTSQD GTLSDTATGA GSEVPREKKA RLQERSRSQT PLSTAAASSQ DAAPPSAPPD
       250        260        270        280        290        300
RSKGAEPSQQ ALGPEQKQAS SRSRSEPPRE RKKTPGLSEQ NGKGALKSER KRVPKTSAQP
       310        320        330        340        350        360
VEGAVEERER KERRESRRLE KGRSQDYPDT PEKRDEGKAA DEEKQRKEED YQTRYRSDPN
       370        380        390        400        410        420
LARYPVKPPP EEQQMRMHAR VSRARHERRH SDVALPRTEA GAALPEGKAG KRAPAAARAS
       430        440        450        460        470        480
PPDSPRAYSA ERTAETRAPG AKQLTNHSPP APRHGPVPAE APELKAQEPL RKQSRLDPSS
       490        500        510        520        530        540
AVLMRKAKRE KVETMLRNDS LSSDQSESVR PSPPKPHRSK RGGKKRQMSV SSSEEEGVST
       550        560        570        580        590        600
PEYTSCEDVE LESESVSEKG DLDYYWLDPA TWHSRETSPI SSHPVTWQPS KEGDRLIGRV
       610        620        630        640        650        660
ILNKRTTMPK DSGALLGLKV VGGKMTDLGR LGAFITKVKK GSLADVVGHL RAGDEVLEWN
       670        680        690        700        710        720
GKPLPGATNE EVYNIILESK SEPQVEIIVS RPIGDIPRIP ESSHPPLESS SSSFESQKME
       730        740        750        760        770        780
RPSISVISPT SPGALKDAPQ VLPGQLSVKL WYDKVGHQLI VNVLQATDLP ARVDGRPRNP
       790        800        810        820        830        840
YVKMYFLPDR SDKSKRRTKT VKKILEPKWN QTFVYSHVHR RDFRERMLEI TVWDQPRVQE
       850        860        870        880        890        900
EESEFLGEIL IELETALLDD EPHWYKLQTH DESSLPLPQP SPFMPRRHIH GESSSKKLQR
       910        920        930        940        950        960
SQRISDSDIS DYEVDDGIGV VPPVGYRSSA RESKSTTLTV PEQQRTTHHR SRSVSPHRGN
       970        980        990       1000       1010       1020
DQGKPRSRLP NVPLQRSLDE IHPTRRSRSP TRHHDASRSP VDHRTRDVDS QYLSEQDSEL
      1030       1040       1050       1060       1070       1080
LMLPRAKRGR SAECLHTTRH LVRHYKTLPP KMPLLQSSSH WNIYSSILPA HTKTKSVTRQ
      1090       1100       1110       1120       1130       1140
DISLHHECFN STVLRFTDEI LVSELQPFLD RARSASTNCL RPDTSLHSPE RERGRWSPSL
      1150       1160       1170       1180       1190       1200
DRRRPPSPRI QIQHASPEND RHSRKSERSS IQKQTRKGTA SDAERVLPTC LSRRGHAAPR
      1210       1220       1230       1240       1250       1260
ATDQPVIRGK HPARSRSSEH SSIRTLCSMH HLVPGGSAPP SPLLTRMHRQ RSPTQSPPAD
      1270       1280       1290       1300       1310       1320
TSFSSRRGRQ LPQVPVRSGS IEQASLVVEE RTRQMKMKVH RFKQTTGSGS SQELDREQYS
      1330       1340       1350       1360       1370       1380
KYNIHKDQYR SCDNVSAKSS DSDVSDVSAI SRTSSASRLS STSFMSEQSE RPRGRISSFT
      1390       1400       1410       1420       1430       1440
PKMQGRRMGT SGRSIMKSTS VSGEMYTLEH NDGSQSDTAV GTVGAGGKKR RSSLSAKVVA
      1450       1460       1470       1480       1490       1500
IVSRRSRSTS QLSQTESGHK KLKSTIQRST ETGMAAEMRK MVRQPSREST DGSINSYSSE
      1510       1520       1530       1540       1550       1560
GNLIFPGVRL GADSQFSDFL DGLGPAQLVG RQTLATPAMG DIQIGMEDKK GQLEVEVIRA
      1570       1580       1590       1600       1610       1620
RSLTQKPGSK STPAPYVKVY LLENGACIAK KKTRIARKTL DPLYQQSLVF DESPQGKVLQ
      1630       1640       1650       1660       1670       1680
VIVWGDYGRM DHKCFMGVAQ ILLEELDLSS MVIGWYKLFP PSSLVDPTLT PLTRRASQSS
      1690
LESSTGPPCI RS         10         20         30         40         50         60
MSSAVGPRGP RPPTVPPPMQ ELPDLSHLTE EERNIIMAVM DRQKEEEEKE EAMLKCVVRD
        70         80         90        100        110        120
MAKPAACKTP RNAENQPHQP SPRLHQQFES YKEQVRKIGE EARRYQGEHK DDAPTCGICH
       130        140        150        160        170        180
KTKFADGCGH LCSYCRTKFC ARCGGRVSLR SNNEDKVVMW VCNLCRKQQE ILTKSGAWFF
       190        200        210        220        230        240
GSGPQQTSQD GTLSDTATGA GSEVPREKKA RLQERSRSQT PLSTAAASSQ DAAPPSAPPD
       250        260        270        280        290        300
RSKGAEPSQQ ALGPEQKQAS SRSRSEPPRE RKKTPGLSEQ NGKGALKSER KRVPKTSAQP
       310        320        330        340        350        360
VEGAVEERER KERRESRRLE KGRSQDYPDT PEKRDEGKAA DEEKQRKEED YQTRYRSDPN
       370        380        390        400        410        420
LARYPVKPPP EEQQMRMHAR VSRARHERRH SDVALPRTEA GAALPEGKAG KRAPAAARAS
       430        440        450        460        470        480
PPDSPRAYSA ERTAETRAPG AKQLTNHSPP APRHGPVPAE APELKAQEPL RKQSRLDPSS
       490        500        510        520        530        540
AVLMRKAKRE KVETMLRNDS LSSDQSESVR PSPPKPHRSK RGGKKRQMSV SSSEEEGVST
       550        560        570        580        590        600
PEYTSCEDVE LESESVSEKG DLDYYWLDPA TWHSRETSPI SSHPVTWQPS KEGDRLIGRV
       610        620        630        640        650        660
ILNKRTTMPK DSGALLGLKV VGGKMTDLGR LGAFITKVKK GSLADVVGHL RAGDEVLEWN
       670        680        690        700        710        720
GKPLPGATNE EVYNIILESK SEPQVEIIVS RPIGDIPRIP ESSHPPLESS SSSFESQKME
       730        740        750        760        770        780
RPSISVISPT SPGALKDAPQ VLPGQLSVKL WYDKVGHQLI VNVLQATDLP ARVDGRPRNP
       790        800        810        820        830        840
YVKMYFLPDR SDKSKRRTKT VKKILEPKWN QTFVYSHVHR RDFRERMLEI TVWDQPRVQE
       850        860        870        880        890        900
EESEFLGEIL IELETALLDD EPHWYKLQTH DESSLPLPQP SPFMPRRHIH GESSSKKLQR
       910        920        930        940        950        960
SQRISDSDIS DYEVDDGIGV VPPVGYRSSA RESKSTTLTV PEQQRTTHHR SRSVSPHRGN
       970        980        990       1000       1010       1020
DQGKPRSRLP NVPLQRSLDE IHPTRRSRSP TRHHDASRSP VDHRTRDVDS QYLSEQDSEL
      1030       1040       1050       1060       1070       1080
LMLPRAKRGR SAECLHTTRH LVRHYKTLPP KMPLLQSSSH WNIYSSILPA HTKTKSVTRQ
      1090       1100       1110       1120       1130       1140
DISLHHECFN STVLRFTDEI LVSELQPFLD RARSASTNCL RPDTSLHSPE RERGRWSPSL
      1150       1160       1170       1180       1190       1200
DRRRPPSPRI QIQHASPEND RHSRKSERSS IQKQTRKGTA SDAERVLPTC LSRRGHAAPR
      1210       1220       1230       1240       1250       1260
ATDQPVIRGK HPARSRSSEH SSIRTLCSMH HLVPGGSAPP SPLLTRMHRQ RSPTQSPPAD
      1270       1280       1290       1300       1310       1320
TSFSSRRGRQ LPQVPVRSGS IEQASLVVEE RTRQMKMKVH RFKQTTGSGS SQELDREQYS
      1330       1340       1350       1360       1370       1380
KYNIHKDQYR SCDNVSAKSS DSDVSDVSAI SRTSSASRLS STSFMSEQSE RPRGRISSFT
      1390       1400       1410       1420       1430       1440
PKMQGRRMGT SGRSIMKSTS VSGEMYTLEH NDGSQSDTAV GTVGAGGKKR RSSLSAKVVA
      1450       1460       1470       1480       1490       1500
IVSRRSRSTS QLSQTESGHK KLKSTIQRST ETGMAAEMRK MVRQPSREST DGSINSYSSE
      1510       1520       1530       1540       1550       1560
GNLIFPGVRL GADSQFSDFL DGLGPAQLVG RQTLATPAMG DIQIGMEDKK GQLEVEVIRA
      1570       1580       1590       1600       1610       1620
RSLTQKPGSK STPAPYVKVY LLENGACIAK KKTRIARKTL DPLYQQSLVF DESPQGKVLQ
      1630       1640       1650       1660       1670       1680
VIVWGDYGRM DHKCFMGVAQ ILLEELDLSS MVIGWYKLFP PSSLVDPTLT PLTRRASQSS
      1690
LESSTGPPCI RS         10         20         30         40         50         60
MSSAVGPRGP RPPTVPPPMQ ELPDLSHLTE EERNIIMAVM DRQKEEEEKE EAMLKCVVRD
        70         80         90        100        110        120
MAKPAACKTP RNAENQPHQP SPRLHQQFES YKEQVRKIGE EARRYQGEHK DDAPTCGICH
       130        140        150        160        170        180
KTKFADGCGH LCSYCRTKFC ARCGGRVSLR SNNEDKVVMW VCNLCRKQQE ILTKSGAWFF
       190        200        210        220        230        240
GSGPQQTSQD GTLSDTATGA GSEVPREKKA RLQERSRSQT PLSTAAASSQ DAAPPSAPPD
       250        260        270        280        290        300
RSKGAEPSQQ ALGPEQKQAS SRSRSEPPRE RKKTPGLSEQ NGKGALKSER KRVPKTSAQP
       310        320        330        340        350        360
VEGAVEERER KERRESRRLE KGRSQDYPDT PEKRDEGKAA DEEKQRKEED YQTRYRSDPN
       370        380        390        400        410        420
LARYPVKPPP EEQQMRMHAR VSRARHERRH SDVALPRTEA GAALPEGKAG KRAPAAARAS
       430        440        450        460        470        480
PPDSPRAYSA ERTAETRAPG AKQLTNHSPP APRHGPVPAE APELKAQEPL RKQSRLDPSS
       490        500        510        520        530        540
AVLMRKAKRE KVETMLRNDS LSSDQSESVR PSPPKPHRSK RGGKKRQMSV SSSEEEGVST
       550        560        570        580        590        600
PEYTSCEDVE LESESVSEKG DLDYYWLDPA TWHSRETSPI SSHPVTWQPS KEGDRLIGRV
       610        620        630        640        650        660
ILNKRTTMPK DSGALLGLKV VGGKMTDLGR LGAFITKVKK GSLADVVGHL RAGDEVLEWN
       670        680        690        700        710        720
GKPLPGATNE EVYNIILESK SEPQVEIIVS RPIGDIPRIP ESSHPPLESS SSSFESQKME
       730        740        750        760        770        780
RPSISVISPT SPGALKDAPQ VLPGQLSVKL WYDKVGHQLI VNVLQATDLP ARVDGRPRNP
       790        800        810        820        830        840
YVKMYFLPDR SDKSKRRTKT VKKILEPKWN QTFVYSHVHR RDFRERMLEI TVWDQPRVQE
       850        860        870        880        890        900
EESEFLGEIL IELETALLDD EPHWYKLQTH DESSLPLPQP SPFMPRRHIH GESSSKKLQR
       910        920        930        940        950        960
SQRISDSDIS DYEVDDGIGV VPPVGYRSSA RESKSTTLTV PEQQRTTHHR SRSVSPHRGN
       970        980        990       1000       1010       1020
DQGKPRSRLP NVPLQRSLDE IHPTRRSRSP TRHHDASRSP VDHRTRDVDS QYLSEQDSEL
      1030       1040       1050       1060       1070       1080
LMLPRAKRGR SAECLHTTRH LVRHYKTLPP KMPLLQSSSH WNIYSSILPA HTKTKSVTRQ
      1090       1100       1110       1120       1130       1140
DISLHHECFN STVLRFTDEI LVSELQPFLD RARSASTNCL RPDTSLHSPE RERGRWSPSL
      1150       1160       1170       1180       1190       1200
DRRRPPSPRI QIQHASPEND RHSRKSERSS IQKQTRKGTA SDAERVLPTC LSRRGHAAPR
      1210       1220       1230       1240       1250       1260
ATDQPVIRGK HPARSRSSEH SSIRTLCSMH HLVPGGSAPP SPLLTRMHRQ RSPTQSPPAD
      1270       1280       1290       1300       1310       1320
TSFSSRRGRQ LPQVPVRSGS IEQASLVVEE RTRQMKMKVH RFKQTTGSGS SQELDREQYS
      1330       1340       1350       1360       1370       1380
KYNIHKDQYR SCDNVSAKSS DSDVSDVSAI SRTSSASRLS STSFMSEQSE RPRGRISSFT
      1390       1400       1410       1420       1430       1440
PKMQGRRMGT SGRSIMKSTS VSGEMYTLEH NDGSQSDTAV GTVGAGGKKR RSSLSAKVVA
      1450       1460       1470       1480       1490       1500
IVSRRSRSTS QLSQTESGHK KLKSTIQRST ETGMAAEMRK MVRQPSREST DGSINSYSSE
      1510       1520       1530       1540       1550       1560
GNLIFPGVRL GADSQFSDFL DGLGPAQLVG RQTLATPAMG DIQIGMEDKK GQLEVEVIRA
      1570       1580       1590       1600       1610       1620
RSLTQKPGSK STPAPYVKVY LLENGACIAK KKTRIARKTL DPLYQQSLVF DESPQGKVLQ
      1630       1640       1650       1660       1670       1680
VIVWGDYGRM DHKCFMGVAQ ILLEELDLSS MVIGWYKLFP PSSLVDPTLT PLTRRASQSS
      1690
LESSTGPPCI RS         10         20         30         40         50         60
MSSAVGPRGP RPPTVPPPMQ ELPDLSHLTE EERNIIMAVM DRQKEEEEKE EAMLKCVVRD
        70         80         90        100        110        120
MAKPAACKTP RNAENQPHQP SPRLHQQFES YKEQVRKIGE EARRYQGEHK DDAPTCGICH
       130        140        150        160        170        180
KTKFADGCGH LCSYCRTKFC ARCGGRVSLR SNNEDKVVMW VCNLCRKQQE ILTKSGAWFF
       190        200        210        220        230        240
GSGPQQTSQD GTLSDTATGA GSEVPREKKA RLQERSRSQT PLSTAAASSQ DAAPPSAPPD
       250        260        270        280        290        300
RSKGAEPSQQ ALGPEQKQAS SRSRSEPPRE RKKTPGLSEQ NGKGALKSER KRVPKTSAQP
       310        320        330        340        350        360
VEGAVEERER KERRESRRLE KGRSQDYPDT PEKRDEGKAA DEEKQRKEED YQTRYRSDPN
       370        380        390        400        410        420
LARYPVKPPP EEQQMRMHAR VSRARHERRH SDVALPRTEA GAALPEGKAG KRAPAAARAS
       430        440        450        460        470        480
PPDSPRAYSA ERTAETRAPG AKQLTNHSPP APRHGPVPAE APELKAQEPL RKQSRLDPSS
       490        500        510        520        530        540
AVLMRKAKRE KVETMLRNDS LSSDQSESVR PSPPKPHRSK RGGKKRQMSV SSSEEEGVST
       550        560        570        580        590        600
PEYTSCEDVE LESESVSEKG DLDYYWLDPA TWHSRETSPI SSHPVTWQPS KEGDRLIGRV
       610        620        630        640        650        660
ILNKRTTMPK DSGALLGLKV VGGKMTDLGR LGAFITKVKK GSLADVVGHL RAGDEVLEWN
       670        680        690        700        710        720
GKPLPGATNE EVYNIILESK SEPQVEIIVS RPIGDIPRIP ESSHPPLESS SSSFESQKME
       730        740        750        760        770        780
RPSISVISPT SPGALKDAPQ VLPGQLSVKL WYDKVGHQLI VNVLQATDLP ARVDGRPRNP
       790        800        810        820        830        840
YVKMYFLPDR SDKSKRRTKT VKKILEPKWN QTFVYSHVHR RDFRERMLEI TVWDQPRVQE
       850        860        870        880        890        900
EESEFLGEIL IELETALLDD EPHWYKLQTH DESSLPLPQP SPFMPRRHIH GESSSKKLQR
       910        920        930        940        950        960
SQRISDSDIS DYEVDDGIGV VPPVGYRSSA RESKSTTLTV PEQQRTTHHR SRSVSPHRGN
       970        980        990       1000       1010       1020
DQGKPRSRLP NVPLQRSLDE IHPTRRSRSP TRHHDASRSP VDHRTRDVDS QYLSEQDSEL
      1030       1040       1050       1060       1070       1080
LMLPRAKRGR SAECLHTTRH LVRHYKTLPP KMPLLQSSSH WNIYSSILPA HTKTKSVTRQ
      1090       1100       1110       1120       1130       1140
DISLHHECFN STVLRFTDEI LVSELQPFLD RARSASTNCL RPDTSLHSPE RERGRWSPSL
      1150       1160       1170       1180       1190       1200
DRRRPPSPRI QIQHASPEND RHSRKSERSS IQKQTRKGTA SDAERVLPTC LSRRGHAAPR
      1210       1220       1230       1240       1250       1260
ATDQPVIRGK HPARSRSSEH SSIRTLCSMH HLVPGGSAPP SPLLTRMHRQ RSPTQSPPAD
      1270       1280       1290       1300       1310       1320
TSFSSRRGRQ LPQVPVRSGS IEQASLVVEE RTRQMKMKVH RFKQTTGSGS SQELDREQYS
      1330       1340       1350       1360       1370       1380
KYNIHKDQYR SCDNVSAKSS DSDVSDVSAI SRTSSASRLS STSFMSEQSE RPRGRISSFT
      1390       1400       1410       1420       1430       1440
PKMQGRRMGT SGRSIMKSTS VSGEMYTLEH NDGSQSDTAV GTVGAGGKKR RSSLSAKVVA
      1450       1460       1470       1480       1490       1500
IVSRRSRSTS QLSQTESGHK KLKSTIQRST ETGMAAEMRK MVRQPSREST DGSINSYSSE
      1510       1520       1530       1540       1550       1560
GNLIFPGVRL GADSQFSDFL DGLGPAQLVG RQTLATPAMG DIQIGMEDKK GQLEVEVIRA
      1570       1580       1590       1600       1610       1620
RSLTQKPGSK STPAPYVKVY LLENGACIAK KKTRIARKTL DPLYQQSLVF DESPQGKVLQ
      1630       1640       1650       1660       1670       1680
VIVWGDYGRM DHKCFMGVAQ ILLEELDLSS MVIGWYKLFP PSSLVDPTLT PLTRRASQSS
      1690
LESSTGPPCI RS         10         20         30         40         50         60
MSSAVGPRGP RPPTVPPPMQ ELPDLSHLTE EERNIIMAVM DRQKEEEEKE EAMLKCVVRD
        70         80         90        100        110        120
MAKPAACKTP RNAENQPHQP SPRLHQQFES YKEQVRKIGE EARRYQGEHK DDAPTCGICH
       130        140        150        160        170        180
KTKFADGCGH LCSYCRTKFC ARCGGRVSLR SNNEDKVVMW VCNLCRKQQE ILTKSGAWFF
       190        200        210        220        230        240
GSGPQQTSQD GTLSDTATGA GSEVPREKKA RLQERSRSQT PLSTAAASSQ DAAPPSAPPD
       250        260        270        280        290        300
RSKGAEPSQQ ALGPEQKQAS SRSRSEPPRE RKKTPGLSEQ NGKGALKSER KRVPKTSAQP
       310        320        330        340        350        360
VEGAVEERER KERRESRRLE KGRSQDYPDT PEKRDEGKAA DEEKQRKEED YQTRYRSDPN
       370        380        390        400        410        420
LARYPVKPPP EEQQMRMHAR VSRARHERRH SDVALPRTEA GAALPEGKAG KRAPAAARAS
       430        440        450        460        470        480
PPDSPRAYSA ERTAETRAPG AKQLTNHSPP APRHGPVPAE APELKAQEPL RKQSRLDPSS
       490        500        510        520        530        540
AVLMRKAKRE KVETMLRNDS LSSDQSESVR PSPPKPHRSK RGGKKRQMSV SSSEEEGVST
       550        560        570        580        590        600
PEYTSCEDVE LESESVSEKG DLDYYWLDPA TWHSRETSPI SSHPVTWQPS KEGDRLIGRV
       610        620        630        640        650        660
ILNKRTTMPK DSGALLGLKV VGGKMTDLGR LGAFITKVKK GSLADVVGHL RAGDEVLEWN
       670        680        690        700        710        720
GKPLPGATNE EVYNIILESK SEPQVEIIVS RPIGDIPRIP ESSHPPLESS SSSFESQKME
       730        740        750        760        770        780
RPSISVISPT SPGALKDAPQ VLPGQLSVKL WYDKVGHQLI VNVLQATDLP ARVDGRPRNP
       790        800        810        820        830        840
YVKMYFLPDR SDKSKRRTKT VKKILEPKWN QTFVYSHVHR RDFRERMLEI TVWDQPRVQE
       850        860        870        880        890        900
EESEFLGEIL IELETALLDD EPHWYKLQTH DESSLPLPQP SPFMPRRHIH GESSSKKLQR
       910        920        930        940        950        960
SQRISDSDIS DYEVDDGIGV VPPVGYRSSA RESKSTTLTV PEQQRTTHHR SRSVSPHRGN
       970        980        990       1000       1010       1020
DQGKPRSRLP NVPLQRSLDE IHPTRRSRSP TRHHDASRSP VDHRTRDVDS QYLSEQDSEL
      1030       1040       1050       1060       1070       1080
LMLPRAKRGR SAECLHTTRH LVRHYKTLPP KMPLLQSSSH WNIYSSILPA HTKTKSVTRQ
      1090       1100       1110       1120       1130       1140
DISLHHECFN STVLRFTDEI LVSELQPFLD RARSASTNCL RPDTSLHSPE RERGRWSPSL
      1150       1160       1170       1180       1190       1200
DRRRPPSPRI QIQHASPEND RHSRKSERSS IQKQTRKGTA SDAERVLPTC LSRRGHAAPR
      1210       1220       1230       1240       1250       1260
ATDQPVIRGK HPARSRSSEH SSIRTLCSMH HLVPGGSAPP SPLLTRMHRQ RSPTQSPPAD
      1270       1280       1290       1300       1310       1320
TSFSSRRGRQ LPQVPVRSGS IEQASLVVEE RTRQMKMKVH RFKQTTGSGS SQELDREQYS
      1330       1340       1350       1360       1370       1380
KYNIHKDQYR SCDNVSAKSS DSDVSDVSAI SRTSSASRLS STSFMSEQSE RPRGRISSFT
      1390       1400       1410       1420       1430       1440
PKMQGRRMGT SGRSIMKSTS VSGEMYTLEH NDGSQSDTAV GTVGAGGKKR RSSLSAKVVA
      1450       1460       1470       1480       1490       1500
IVSRRSRSTS QLSQTESGHK KLKSTIQRST ETGMAAEMRK MVRQPSREST DGSINSYSSE
      1510       1520       1530       1540       1550       1560
GNLIFPGVRL GADSQFSDFL DGLGPAQLVG RQTLATPAMG DIQIGMEDKK GQLEVEVIRA
      1570       1580       1590       1600       1610       1620
RSLTQKPGSK STPAPYVKVY LLENGACIAK KKTRIARKTL DPLYQQSLVF DESPQGKVLQ
      1630       1640       1650       1660       1670       1680
VIVWGDYGRM DHKCFMGVAQ ILLEELDLSS MVIGWYKLFP PSSLVDPTLT PLTRRASQSS
      1690
LESSTGPPCI RS         10         20         30         40         50         60
MSSAVGPRGP RPPTVPPPMQ ELPDLSHLTE EERNIIMAVM DRQKEEEEKE EAMLKCVVRD
        70         80         90        100        110        120
MAKPAACKTP RNAENQPHQP SPRLHQQFES YKEQVRKIGE EARRYQGEHK DDAPTCGICH
       130        140        150        160        170        180
KTKFADGCGH LCSYCRTKFC ARCGGRVSLR SNNEDKVVMW VCNLCRKQQE ILTKSGAWFF
       190        200        210        220        230        240
GSGPQQTSQD GTLSDTATGA GSEVPREKKA RLQERSRSQT PLSTAAASSQ DAAPPSAPPD
       250        260        270        280        290        300
RSKGAEPSQQ ALGPEQKQAS SRSRSEPPRE RKKTPGLSEQ NGKGALKSER KRVPKTSAQP
       310        320        330        340        350        360
VEGAVEERER KERRESRRLE KGRSQDYPDT PEKRDEGKAA DEEKQRKEED YQTRYRSDPN
       370        380        390        400        410        420
LARYPVKPPP EEQQMRMHAR VSRARHERRH SDVALPRTEA GAALPEGKAG KRAPAAARAS
       430        440        450        460        470        480
PPDSPRAYSA ERTAETRAPG AKQLTNHSPP APRHGPVPAE APELKAQEPL RKQSRLDPSS
       490        500        510        520        530        540
AVLMRKAKRE KVETMLRNDS LSSDQSESVR PSPPKPHRSK RGGKKRQMSV SSSEEEGVST
       550        560        570        580        590        600
PEYTSCEDVE LESESVSEKG DLDYYWLDPA TWHSRETSPI SSHPVTWQPS KEGDRLIGRV
       610        620        630        640        650        660
ILNKRTTMPK DSGALLGLKV VGGKMTDLGR LGAFITKVKK GSLADVVGHL RAGDEVLEWN
       670        680        690        700        710        720
GKPLPGATNE EVYNIILESK SEPQVEIIVS RPIGDIPRIP ESSHPPLESS SSSFESQKME
       730        740        750        760        770        780
RPSISVISPT SPGALKDAPQ VLPGQLSVKL WYDKVGHQLI VNVLQATDLP ARVDGRPRNP
       790        800        810        820        830        840
YVKMYFLPDR SDKSKRRTKT VKKILEPKWN QTFVYSHVHR RDFRERMLEI TVWDQPRVQE
       850        860        870        880        890        900
EESEFLGEIL IELETALLDD EPHWYKLQTH DESSLPLPQP SPFMPRRHIH GESSSKKLQR
       910        920        930        940        950        960
SQRISDSDIS DYEVDDGIGV VPPVGYRSSA RESKSTTLTV PEQQRTTHHR SRSVSPHRGN
       970        980        990       1000       1010       1020
DQGKPRSRLP NVPLQRSLDE IHPTRRSRSP TRHHDASRSP VDHRTRDVDS QYLSEQDSEL
      1030       1040       1050       1060       1070       1080
LMLPRAKRGR SAECLHTTRH LVRHYKTLPP KMPLLQSSSH WNIYSSILPA HTKTKSVTRQ
      1090       1100       1110       1120       1130       1140
DISLHHECFN STVLRFTDEI LVSELQPFLD RARSASTNCL RPDTSLHSPE RERGRWSPSL
      1150       1160       1170       1180       1190       1200
DRRRPPSPRI QIQHASPEND RHSRKSERSS IQKQTRKGTA SDAERVLPTC LSRRGHAAPR
      1210       1220       1230       1240       1250       1260
ATDQPVIRGK HPARSRSSEH SSIRTLCSMH HLVPGGSAPP SPLLTRMHRQ RSPTQSPPAD
      1270       1280       1290       1300       1310       1320
TSFSSRRGRQ LPQVPVRSGS IEQASLVVEE RTRQMKMKVH RFKQTTGSGS SQELDREQYS
      1330       1340       1350       1360       1370       1380
KYNIHKDQYR SCDNVSAKSS DSDVSDVSAI SRTSSASRLS STSFMSEQSE RPRGRISSFT
      1390       1400       1410       1420       1430       1440
PKMQGRRMGT SGRSIMKSTS VSGEMYTLEH NDGSQSDTAV GTVGAGGKKR RSSLSAKVVA
      1450       1460       1470       1480       1490       1500
IVSRRSRSTS QLSQTESGHK KLKSTIQRST ETGMAAEMRK MVRQPSREST DGSINSYSSE
      1510       1520       1530       1540       1550       1560
GNLIFPGVRL GADSQFSDFL DGLGPAQLVG RQTLATPAMG DIQIGMEDKK GQLEVEVIRA
      1570       1580       1590       1600       1610       1620
RSLTQKPGSK STPAPYVKVY LLENGACIAK KKTRIARKTL DPLYQQSLVF DESPQGKVLQ
      1630       1640       1650       1660       1670       1680
VIVWGDYGRM DHKCFMGVAQ ILLEELDLSS MVIGWYKLFP PSSLVDPTLT PLTRRASQSS
      1690
LESSTGPPCI RS         10         20         30         40         50         60
MSSAVGPRGP RPPTVPPPMQ ELPDLSHLTE EERNIIMAVM DRQKEEEEKE EAMLKCVVRD
        70         80         90        100        110        120
MAKPAACKTP RNAENQPHQP SPRLHQQFES YKEQVRKIGE EARRYQGEHK DDAPTCGICH
       130        140        150        160        170        180
KTKFADGCGH LCSYCRTKFC ARCGGRVSLR SNNEDKVVMW VCNLCRKQQE ILTKSGAWFF
       190        200        210        220        230        240
GSGPQQTSQD GTLSDTATGA GSEVPREKKA RLQERSRSQT PLSTAAASSQ DAAPPSAPPD
       250        260        270        280        290        300
RSKGAEPSQQ ALGPEQKQAS SRSRSEPPRE RKKTPGLSEQ NGKGALKSER KRVPKTSAQP
       310        320        330        340        350        360
VEGAVEERER KERRESRRLE KGRSQDYPDT PEKRDEGKAA DEEKQRKEED YQTRYRSDPN
       370        380        390        400        410        420
LARYPVKPPP EEQQMRMHAR VSRARHERRH SDVALPRTEA GAALPEGKAG KRAPAAARAS
       430        440        450        460        470        480
PPDSPRAYSA ERTAETRAPG AKQLTNHSPP APRHGPVPAE APELKAQEPL RKQSRLDPSS
       490        500        510        520        530        540
AVLMRKAKRE KVETMLRNDS LSSDQSESVR PSPPKPHRSK RGGKKRQMSV SSSEEEGVST
       550        560        570        580        590        600
PEYTSCEDVE LESESVSEKG DLDYYWLDPA TWHSRETSPI SSHPVTWQPS KEGDRLIGRV
       610        620        630        640        650        660
ILNKRTTMPK DSGALLGLKV VGGKMTDLGR LGAFITKVKK GSLADVVGHL RAGDEVLEWN
       670        680        690        700        710        720
GKPLPGATNE EVYNIILESK SEPQVEIIVS RPIGDIPRIP ESSHPPLESS SSSFESQKME
       730        740        750        760        770        780
RPSISVISPT SPGALKDAPQ VLPGQLSVKL WYDKVGHQLI VNVLQATDLP ARVDGRPRNP
       790        800        810        820        830        840
YVKMYFLPDR SDKSKRRTKT VKKILEPKWN QTFVYSHVHR RDFRERMLEI TVWDQPRVQE
       850        860        870        880        890        900
EESEFLGEIL IELETALLDD EPHWYKLQTH DESSLPLPQP SPFMPRRHIH GESSSKKLQR
       910        920        930        940        950        960
SQRISDSDIS DYEVDDGIGV VPPVGYRSSA RESKSTTLTV PEQQRTTHHR SRSVSPHRGN
       970        980        990       1000       1010       1020
DQGKPRSRLP NVPLQRSLDE IHPTRRSRSP TRHHDASRSP VDHRTRDVDS QYLSEQDSEL
      1030       1040       1050       1060       1070       1080
LMLPRAKRGR SAECLHTTRH LVRHYKTLPP KMPLLQSSSH WNIYSSILPA HTKTKSVTRQ
      1090       1100       1110       1120       1130       1140
DISLHHECFN STVLRFTDEI LVSELQPFLD RARSASTNCL RPDTSLHSPE RERGRWSPSL
      1150       1160       1170       1180       1190       1200
DRRRPPSPRI QIQHASPEND RHSRKSERSS IQKQTRKGTA SDAERVLPTC LSRRGHAAPR
      1210       1220       1230       1240       1250       1260
ATDQPVIRGK HPARSRSSEH SSIRTLCSMH HLVPGGSAPP SPLLTRMHRQ RSPTQSPPAD
      1270       1280       1290       1300       1310       1320
TSFSSRRGRQ LPQVPVRSGS IEQASLVVEE RTRQMKMKVH RFKQTTGSGS SQELDREQYS
      1330       1340       1350       1360       1370       1380
KYNIHKDQYR SCDNVSAKSS DSDVSDVSAI SRTSSASRLS STSFMSEQSE RPRGRISSFT
      1390       1400       1410       1420       1430       1440
PKMQGRRMGT SGRSIMKSTS VSGEMYTLEH NDGSQSDTAV GTVGAGGKKR RSSLSAKVVA
      1450       1460       1470       1480       1490       1500
IVSRRSRSTS QLSQTESGHK KLKSTIQRST ETGMAAEMRK MVRQPSREST DGSINSYSSE
      1510       1520       1530       1540       1550       1560
GNLIFPGVRL GADSQFSDFL DGLGPAQLVG RQTLATPAMG DIQIGMEDKK GQLEVEVIRA
      1570       1580       1590       1600       1610       1620
RSLTQKPGSK STPAPYVKVY LLENGACIAK KKTRIARKTL DPLYQQSLVF DESPQGKVLQ
      1630       1640       1650       1660       1670       1680
VIVWGDYGRM DHKCFMGVAQ ILLEELDLSS MVIGWYKLFP PSSLVDPTLT PLTRRASQSS
      1690
LESSTGPPCI RS

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q86UR5-1-unknown	MSSAVG...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q86UR5-1-unknown	MSSAVG...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87740
Q86UR5-1-unknown	MSSAVG...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87741
Q86UR5-1-unknown	MSSAVG...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87742
Q86UR5-1-unknown	MSSAVG...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87743
Q86UR5-1-unknown	MSSAVG...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87744
Q86UR5-1-unknown	MSSAVG...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87745
Q86UR5-1-unknown	MSSAVG...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87746
Q86UR5-608-unknown	MPKDSG...	608	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000411235
Q86UR5-608-unknown	MPKDSG...	608	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000389503
Q86UR5-608-unknown	MPKDSG...	608	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt199987
Q86UR5-608-unknown	MPKDSG...	608	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt199988
Q86UR5-608-unknown	MPKDSG...	608	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt199989
Q86UR5-608-unknown	MPKDSG...	608	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt199990
Q86UR5-608-unknown	MPKDSG...	608	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt199991
Q86UR5-608-unknown	MPKDSG...	608	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt199992
Q86UR5-608-unknown	MPKDSG...	608	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt199993
Q86UR5-608-unknown	MPKDSG...	608	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt199994
Q86UR5-776-unknown	RPRNPY...	776	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000359448
Q86UR5-776-unknown	RPRNPY...	776	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt200292
Q86UR5-776-unknown	RPRNPY...	776	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt200293
Q86UR5-776-unknown	RPRNPY...	776	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt200294
Q86UR5-776-unknown	RPRNPY...	776	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt200295
Q86UR5-776-unknown	RPRNPY...	776	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt200296
Q86UR5-776-unknown	RPRNPY...	776	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt200297
Q86UR5-776-unknown	RPRNPY...	776	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt200298
Q86UR5-776-unknown	RPRNPY...	776	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt200299
Q86UR5-1474-unknown	MAAEMR...	1474	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000402273
Q86UR5-1474-unknown	MAAEMR...	1474	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt200709
Q86UR5-1474-unknown	MAAEMR...	1474	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt200710
Q86UR5-1474-unknown	MAAEMR...	1474	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt200711
Q86UR5-1474-unknown	MAAEMR...	1474	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt200712
Q86UR5-1474-unknown	MAAEMR...	1474	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt200713
Q86UR5-1474-unknown	MAAEMR...	1474	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt200715
Q86UR5-1474-unknown	MAAEMR...	1474	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt200714
Q86UR5-1522-unknown	GLGPAQ...	1522	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174261
Q86UR5-1522-unknown	GLGPAQ...	1522	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174262
Q86UR5-1522-unknown	GLGPAQ...	1522	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174263
Q86UR5-1522-unknown	GLGPAQ...	1522	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174264
Q86UR5-1522-unknown	GLGPAQ...	1522	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174265
Q86UR5-1522-unknown	GLGPAQ...	1522	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174266
Q86UR5-1522-	GLGPAQ...	1522		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LHTTRH	1039	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83358
...LHTTRH	1039	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt93626
...LHTTRH	1039	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt93627
...NGACIA	1588	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000389503
...PCIRS	1692	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...PCIRS	1692	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83365
...PCIRS	1692	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83364
...PCIRS	1692	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83363
...PCIRS	1692	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83362
...PCIRS	1692	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83361
...PCIRS	1692	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83359
...PCIRS	1692	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83360

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)