Q86UU1: Pleckstrin homology-like domain family B member 1

General Information

Protein names	- Pleckstrin homology-like domain family B member 1 - Protein LL5-alpha
Gene names	PHLDB1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q86UU1

2 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDALNRNQIG PGCQTQTMVQ KGPLDLIETG KGLKVQTDKP HLVSLGSGRL STAITLLPLE
        70         80         90        100        110        120
EGRTVIGSAA RDISLQGPGL APEHCYIENL RGTLTLYPCG NACTIDGLPV RQPTRLTQGC
       130        140        150        160        170        180
MLCLGQSTFL RFNHPAEAKW MKSMIPAGGR APGPPYSPVP AESESLVNGN HTPQTATRGP
       190        200        210        220        230        240
SACASHSSLV SSIEKDLQEI MDSLVLEEPG AAGKKPAATS PLSPMANGGR YLLSPPTSPG
       250        260        270        280        290        300
AMSVGSSYEN TSPAFSPLSS PASSGSCASH SPSGQEPGPS VPPLVPARSS SYHLALQPPQ
       310        320        330        340        350        360
SRPSGARSES PRLSRKGGHE RPPSPGLRGL LTDSPAATVL AEARRATESP RLGGQLPVVA
       370        380        390        400        410        420
ISLSEYPASG ALSQPTSIPG SPKFQPPVPA PRNKIGTLQD RPPSPFREPP GSERVLTTSP
       430        440        450        460        470        480
SRQLVGRTFS DGLATRTLQP PESPRLGRRG LDSMRELPPL SPSLSRRALS PLPTRTTPDP
       490        500        510        520        530        540
KLNREVAESP RPRRWAAHGA SPEDFSLTLG ARGRRTRSPS PTLGESLAPH KGSFSGRLSP
       550        560        570        580        590        600
AYSLGSLTGA SPCQSPCVQR KLSSGDLRVP VTRERKNSIT EISDNEDDLL EYHRRQRQER
       610        620        630        640        650        660
LREQEMERLE RQRLETILNL CAEYSRADGG PEAGELPSIG EATAALALAG RRPSRGLAGA
       670        680        690        700        710        720
SGRSSEEPGV ATQRLWESME RSDEENLKEE CSSTESTQQE HEDAPSTKLQ GEVLALEEER
       730        740        750        760        770        780
AQVLGHVEQL KVRVKELEQQ LQESAREAEM ERALLQGERE AERALLQKEQ KAVDQLQEKL
       790        800        810        820        830        840
VALETGIQKE RDKEAEALET ETKLFEDLEF QQLERESRVE EERELAGQGL LRSKAELLRS
       850        860        870        880        890        900
IAKRKERLAI LDSQAGQIRA QAVQESERLA RDKNASLQLL QKEKEKLTVL ERRYHSLTGG
       910        920        930        940        950        960
RPFPKTTSTL KEMEKLLLPA VDLEQWYQEL MAGLGTGPAA ASPHSSPPPL PAKASRQLQV
       970        980        990       1000       1010       1020
YRSKMDGEAT SPLPRTRSGP LPSSSGSSSS SSQLSVATLG RSPSPKSALL TQNGTGSLPR
      1030       1040       1050       1060       1070       1080
NLAATLQDIE TKRQLALQQK GQQVIEEQRR RLAELKQKAA AEAQCQWDAL HGAAPFPAGP
      1090       1100       1110       1120       1130       1140
SGFPPLMHHS ILHHLPAGRE RGEEGEHAYD TLSLESSDSM ETSISTGGNS ACSPDNMSSA
      1150       1160       1170       1180       1190       1200
SGLDMGKIEE MEKMLKEAHA EKNRLMESRE REMELRRQAL EEERRRREQV ERRLQSESAR
      1210       1220       1230       1240       1250       1260
RQQLVEKEVK MREKQFSQAR PLTRYLPIRK EDFDLKTHIE SSGHGVDTCL HVVLSSKVCR
      1270       1280       1290       1300       1310       1320
GYLVKMGGKI KSWKKRWFVF DRLKRTLSYY VDKHETKLKG VIYFQAIEEV YYDHLRSAAK
      1330       1340       1350       1360       1370
KRFFRFTMVT ESPNPALTFC VKTHDRLYYM VAPSAEAMRI WMDVIVTGAE GYTQFMN

Isoforms

- Isoform 2 of Pleckstrin homology-like domain family B member 1 - Isoform 3 of Pleckstrin homology-like domain family B member 1

Sequence View

        10         20         30         40         50         60
MDALNRNQIG PGCQTQTMVQ KGPLDLIETG KGLKVQTDKP HLVSLGSGRL STAITLLPLE
        70         80         90        100        110        120
EGRTVIGSAA RDISLQGPGL APEHCYIENL RGTLTLYPCG NACTIDGLPV RQPTRLTQGC
       130        140        150        160        170        180
MLCLGQSTFL RFNHPAEAKW MKSMIPAGGR APGPPYSPVP AESESLVNGN HTPQTATRGP
       190        200        210        220        230        240
SACASHSSLV SSIEKDLQEI MDSLVLEEPG AAGKKPAATS PLSPMANGGR YLLSPPTSPG
       250        260        270        280        290        300
AMSVGSSYEN TSPAFSPLSS PASSGSCASH SPSGQEPGPS VPPLVPARSS SYHLALQPPQ
       310        320        330        340        350        360
SRPSGARSES PRLSRKGGHE RPPSPGLRGL LTDSPAATVL AEARRATESP RLGGQLPVVA
       370        380        390        400        410        420
ISLSEYPASG ALSQPTSIPG SPKFQPPVPA PRNKIGTLQD RPPSPFREPP GSERVLTTSP
       430        440        450        460        470        480
SRQLVGRTFS DGLATRTLQP PESPRLGRRG LDSMRELPPL SPSLSRRALS PLPTRTTPDP
       490        500        510        520        530        540
KLNREVAESP RPRRWAAHGA SPEDFSLTLG ARGRRTRSPS PTLGESLAPH KGSFSGRLSP
       550        560        570        580        590        600
AYSLGSLTGA SPCQSPCVQR KLSSGDLRVP VTRERKNSIT EISDNEDDLL EYHRRQRQER
       610        620        630        640        650        660
LREQEMERLE RQRLETILNL CAEYSRADGG PEAGELPSIG EATAALALAG RRPSRGLAGA
       670        680        690        700        710        720
SGRSSEEPGV ATQRLWESME RSDEENLKEE CSSTESTQQE HEDAPSTKLQ GEVLALEEER
       730        740        750        760        770        780
AQVLGHVEQL KVRVKELEQQ LQESAREAEM ERALLQGERE AERALLQKEQ KAVDQLQEKL
       790        800        810        820        830        840
VALETGIQKE RDKEAEALET ETKLFEDLEF QQLERESRVE EERELAGQGL LRSKAELLRS
       850        860        870        880        890        900
IAKRKERLAI LDSQAGQIRA QAVQESERLA RDKNASLQLL QKEKEKLTVL ERRYHSLTGG
       910        920        930        940        950        960
RPFPKTTSTL KEMEKLLLPA VDLEQWYQEL MAGLGTGPAA ASPHSSPPPL PAKASRQLQV
       970        980        990       1000       1010       1020
YRSKMDGEAT SPLPRTRSGP LPSSSGSSSS SSQLSVATLG RSPSPKSALL TQNGTGSLPR
      1030       1040       1050       1060       1070       1080
NLAATLQDIE TKRQLALQQK GQQVIEEQRR RLAELKQKAA AEAQCQWDAL HGAAPFPAGP
      1090       1100       1110       1120       1130       1140
SGFPPLMHHS ILHHLPAGRE RGEEGEHAYD TLSLESSDSM ETSISTGGNS ACSPDNMSSA
      1150       1160       1170       1180       1190       1200
SGLDMGKIEE MEKMLKEAHA EKNRLMESRE REMELRRQAL EEERRRREQV ERRLQSESAR
      1210       1220       1230       1240       1250       1260
RQQLVEKEVK MREKQFSQAR PLTRYLPIRK EDFDLKTHIE SSGHGVDTCL HVVLSSKVCR
      1270       1280       1290       1300       1310       1320
GYLVKMGGKI KSWKKRWFVF DRLKRTLSYY VDKHETKLKG VIYFQAIEEV YYDHLRSAAK
      1330       1340       1350       1360       1370
KRFFRFTMVT ESPNPALTFC VKTHDRLYYM VAPSAEAMRI WMDVIVTGAE GYTQFMN         10         20         30         40         50         60
MDALNRNQIG PGCQTQTMVQ KGPLDLIETG KGLKVQTDKP HLVSLGSGRL STAITLLPLE
        70         80         90        100        110        120
EGRTVIGSAA RDISLQGPGL APEHCYIENL RGTLTLYPCG NACTIDGLPV RQPTRLTQGC
       130        140        150        160        170        180
MLCLGQSTFL RFNHPAEAKW MKSMIPAGGR APGPPYSPVP AESESLVNGN HTPQTATRGP
       190        200        210        220        230        240
SACASHSSLV SSIEKDLQEI MDSLVLEEPG AAGKKPAATS PLSPMANGGR YLLSPPTSPG
       250        260        270        280        290        300
AMSVGSSYEN TSPAFSPLSS PASSGSCASH SPSGQEPGPS VPPLVPARSS SYHLALQPPQ
       310        320        330        340        350        360
SRPSGARSES PRLSRKGGHE RPPSPGLRGL LTDSPAATVL AEARRATESP RLGGQLPVVA
       370        380        390        400        410        420
ISLSEYPASG ALSQPTSIPG SPKFQPPVPA PRNKIGTLQD RPPSPFREPP GSERVLTTSP
       430        440        450        460        470        480
SRQLVGRTFS DGLATRTLQP PESPRLGRRG LDSMRELPPL SPSLSRRALS PLPTRTTPDP
       490        500        510        520        530        540
KLNREVAESP RPRRWAAHGA SPEDFSLTLG ARGRRTRSPS PTLGESLAPH KGSFSGRLSP
       550        560        570        580        590        600
AYSLGSLTGA SPCQSPCVQR KLSSGDLRVP VTRERKNSIT EISDNEDDLL EYHRRQRQER
       610        620        630        640        650        660
LREQEMERLE RQRLETILNL CAEYSRADGG PEAGELPSIG EATAALALAG RRPSRGLAGA
       670        680        690        700        710        720
SGRSSEEPGV ATQRLWESME RSDEENLKEE CSSTESTQQE HEDAPSTKLQ GEVLALEEER
       730        740        750        760        770        780
AQVLGHVEQL KVRVKELEQQ LQESAREAEM ERALLQGERE AERALLQKEQ KAVDQLQEKL
       790        800        810        820        830        840
VALETGIQKE RDKEAEALET ETKLFEDLEF QQLERESRVE EERELAGQGL LRSKAELLRS
       850        860        870        880        890        900
IAKRKERLAI LDSQAGQIRA QAVQESERLA RDKNASLQLL QKEKEKLTVL ERRYHSLTGG
       910        920        930        940        950        960
RPFPKTTSTL KEMEKLLLPA VDLEQWYQEL MAGLGTGPAA ASPHSSPPPL PAKASRQLQV
       970        980        990       1000       1010       1020
YRSKMDGEAT SPLPRTRSGP LPSSSGSSSS SSQLSVATLG RSPSPKSALL TQNGTGSLPR
      1030       1040       1050       1060       1070       1080
NLAATLQDIE TKRQLALQQK GQQVIEEQRR RLAELKQKAA AEAQCQWDAL HGAAPFPAGP
      1090       1100       1110       1120       1130       1140
SGFPPLMHHS ILHHLPAGRE RGEEGEHAYD TLSLESSDSM ETSISTGGNS ACSPDNMSSA
      1150       1160       1170       1180       1190       1200
SGLDMGKIEE MEKMLKEAHA EKNRLMESRE REMELRRQAL EEERRRREQV ERRLQSESAR
      1210       1220       1230       1240       1250       1260
RQQLVEKEVK MREKQFSQAR PLTRYLPIRK EDFDLKTHIE SSGHGVDTCL HVVLSSKVCR
      1270       1280       1290       1300       1310       1320
GYLVKMGGKI KSWKKRWFVF DRLKRTLSYY VDKHETKLKG VIYFQAIEEV YYDHLRSAAK
      1330       1340       1350       1360       1370
KRFFRFTMVT ESPNPALTFC VKTHDRLYYM VAPSAEAMRI WMDVIVTGAE GYTQFMN

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q86UU1-1-unknown	MDALNR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q86UU1-1-unknown	MDALNR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85083
Q86UU1-1-unknown	MDALNR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85084
Q86UU1-165-unknown	SLVNGN...	165	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6577
Q86UU1-165-unknown	SLVNGN...	165	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt145346
Q86UU1-165-unknown	SLVNGN...	165	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt145347

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PAESES	164	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6577
...PAESES	164	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt128637
...PAESES	164	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt128638
...TQFMN	1377	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...TQFMN	1377	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt80701

TopFIND

Q86UU1: Pleckstrin homology-like domain family B member 1

General Information

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Physiological Relevance:

Evidence Codes:

Methodology:

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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates