Q86UU9: Tachykinin-4

General Information

Protein names	- Tachykinin-4 - Preprotachykinin-C - PPT-C - Endokinin-A - EKA - Endokinin-A/B - EKA/B - Endokinin-C - EKC
Gene names	TAC4
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q86UU9

4 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

10 20 30 40 50 60
MLPCLALLLL MELSVCTVAG DGGEEQTLST EAETWVIVAL EEGAGPSIQL QLQEVKTGKA
70 80 90 100 110
SQFFGLMGKR VGGRPLIQPR RKKAYQLEHT FQGLLGKRSL FTEGREDEAQ GSE

Isoforms

- Isoform 2 of Tachykinin-4 - Isoform 3 of Tachykinin-4 - Isoform 4 of Tachykinin-4 - Isoform 5 of Tachykinin-4

Sequence View

        10         20         30         40         50         60
MLPCLALLLL MELSVCTVAG DGGEEQTLST EAETWVIVAL EEGAGPSIQL QLQEVKTGKA
        70         80         90        100        110
SQFFGLMGKR VGGRPLIQPR RKKAYQLEHT FQGLLGKRSL FTEGREDEAQ GSE         10         20         30         40         50         60
MLPCLALLLL MELSVCTVAG DGGEEQTLST EAETWVIVAL EEGAGPSIQL QLQEVKTGKA
        70         80         90        100        110
SQFFGLMGKR VGGRPLIQPR RKKAYQLEHT FQGLLGKRSL FTEGREDEAQ GSE         10         20         30         40         50         60
MLPCLALLLL MELSVCTVAG DGGEEQTLST EAETWVIVAL EEGAGPSIQL QLQEVKTGKA
        70         80         90        100        110
SQFFGLMGKR VGGRPLIQPR RKKAYQLEHT FQGLLGKRSL FTEGREDEAQ GSE         10         20         30         40         50         60
MLPCLALLLL MELSVCTVAG DGGEEQTLST EAETWVIVAL EEGAGPSIQL QLQEVKTGKA
        70         80         90        100        110
SQFFGLMGKR VGGRPLIQPR RKKAYQLEHT FQGLLGKRSL FTEGREDEAQ GSE

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q86UU9-1-unknown	MLPCLA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92220
Q86UU9-1-unknown	MLPCLA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92221
Q86UU9-1-unknown	MLPCLA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92222
Q86UU9-1-unknown	MLPCLA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92223
Q86UU9-21-unknown	DGGEEQ...	21	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q86UU9-83-unknown	KAYQLE...	83	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC257
Q86UU9-83-unknown	KAYQLE...	83	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141087
Q86UU9-84-unknown	AYQLEH...	84	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC259
Q86UU9-84-unknown	AYQLEH...	84	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141157
Q86UU9-84-unknown	AYQLEH...	84	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196613

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QPRRKK	82	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC257
...QPRRKK	82	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124239
...QPRRKK	82	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154093
...PRRKKA	83	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC259
...PRRKKA	83	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124314
...PRRKKA	83	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154098
...AQGSE	113	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt87838
...AQGSE	113	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt87841

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
AMPQ_HUMAN	82	RRKK.\|.KAYQ	inferred from experiment	unknown	MEROPS	Tsujimoto M	Maruyama M et al.:Laeverin/aminopeptidase Q, a no... (M01.026)	17525158,
AMPQ_HUMAN	83	RKKA.\|.AYQL	inferred from experiment	unknown	MEROPS	Tsujimoto M	Maruyama M et al.:Laeverin/aminopeptidase Q, a no... (M01.026)	17525158,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)