Q86WA6: Valacyclovir hydrolase

General Information

Protein names	- Valacyclovir hydrolase - VACVase - Valacyclovirase - 3.1.-.- - Biphenyl hydrolase-like protein - Biphenyl hydrolase-related protein - Bph-rp - Breast epithelial mucin-associated antigen - MCNAA
Gene names	BPHL
Organism	Homo sapiens
Protease Family
Protease ID	S33.982
Chromosome location
UniProt ID	Q86WA6

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVAVLGGRGV LRLRLLLSAL KPGIHVPRAG PAAAFGTSVT SAKVAVNGVQ LHYQQTGEGD
        70         80         90        100        110        120
HAVLLLPGML GSGETDFGPQ LKNLNKKLFT VVAWDPRGYG HSRPPDRDFP ADFFERDAKD
       130        140        150        160        170        180
AVDLMKALKF KKVSLLGWSD GGITALIAAA KYPSYIHKMV IWGANAYVTD EDSMIYEGIR
       190        200        210        220        230        240
DVSKWSERTR KPLEALYGYD YFARTCEKWV DGIRQFKHLP DGNICRHLLP RVQCPALIVH
       250        260        270        280        290
GEKDPLVPRF HADFIHKHVK GSRLHLMPEG KHNLHLRFAD EFNKLAEDFL Q

Isoforms

- Isoform 2 of Valacyclovir hydrolase

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q86WA6-33-	AAFGTS...	33		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q86WA6-36-	GTSVTS...	36		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q86WA6-38-unknown	SVTSAK...	38	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q86WA6-38-unknown	SVTSAK...	38	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt115351

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...EDFLQ	291	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...EDFLQ	291	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt64189
...EDFLQ	291		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)