Q8BH43: Wiskott-Aldrich syndrome protein family member 2

General Information

Protein names	- Wiskott-Aldrich syndrome protein family member 2 - WASP family protein member 2 - Protein WAVE-2
Gene names	Wasf2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8BH43

3 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPLVTRNIEP RHLCRQTLPS DTSELECRTN ITLANVIRQL GSLSKYAEDI FGEICTQASA
        70         80         90        100        110        120
FASRVNSLAE RVDRVQVKVT QLDPKEEEVS LQGINTRKAF RSSTTQDQKL FDRNSLPVPV
       130        140        150        160        170        180
LETYNSCDAP PPLNNLSPYR DDGKEALKFY TNPSYFFDLW KEKMLQDTKD IMKEKRKHRK
       190        200        210        220        230        240
EKKDNPNRGN VNPRKIKTRK EEWEKMKMGQ EFVESKERLG PSGYSSTLVY QNGSIGSVEN
       250        260        270        280        290        300
VDAASYPPPP QSDSASSPSP SFSEDNLPPP PAEFSYPADN QRGSVLAGPK RTSMVSPSHP
       310        320        330        340        350        360
PPAPPLSSPP GPKPGFAPPP APPPPPPMSV PPPLPSMGFG SPGTPPPPSP PSFPPHPDFA
       370        380        390        400        410        420
APPPPPPPPA ADYPMPPPPL SQPSGGAPPP PPPPPPPGPP PLPFSGADGQ PAAPPPPPPS
       430        440        450        460        470        480
EATKPKSSLP AVSDARSDLL SAIRQGFQLR RVEEQREQEK RDVVGNDVAT ILSRRIAVEY
       490
SDSEDDSSEF DEDDWSD

Isoforms

Sequence View

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Protease Assignment Confidence:

Evidence Names:

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Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q8BH43-1-unknown	MPLVTR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8BH43-89-unknown	VSLQGI...	89	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30727
Q8BH43-161-unknown	KEKMLQ...	161	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29235

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QLDPKE	85	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000117314
...PKEEEV	88	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30727
...FFDLWK	160	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29235
...DDWSD	497	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	88	EEEV.\|.VSLQ	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> WASF2_MOUSE @88
CATD_MOUSE	160	DLWK.\|.KEKM	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> WASF2_MOUSE @160

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)