TopFIND 4.0

Q8BHG1: Nardilysin

General Information

Protein names
- Nardilysin
- 3.4.24.61
- N-arginine dibasic convertase
- NRD convertase
- NRD-C
- Nardilysin convertase {ECO:0000250|UniProtKB:O43847}
Gene names Nrd1
Organism Mus musculus
Protease Family M16.005
Protease ID M16.005
Chromosome location
UniProt ID Q8BHG1

3

N-termini

2

C-termini

0

Cleavages

1

Substrates

Sequence

        10         20         30         40         50         60 
MLRRVAVAAV CVTGRKLRCE AGRELTALGR IEARGLCEES SKPFPTLTMP GRNKAKSTCS 
        70         80         90        100        110        120 
CPDLQPNGQD LGESGRLARL GADESEEEGR SFSNVGDPEI IKSPSDPKQY RYIKLQNGLQ 
       130        140        150        160        170        180 
ALLISDLSNV EGKTGNATDE EEEEEEEEEE EDDDDDDDDD DDDEDSGAEI QDDDEEGFDD 
       190        200        210        220        230        240 
EEEFDDDDDD EHDDDDLENE ENELEELEER VEARKKTTEK QSAAALCVGV GSFADPDDLP 
       250        260        270        280        290        300 
GLAHFLEHMV FMGSLKYPDE NGFDAFLKKH GGSDNASTDC ERTVFQFDVQ RKYFKEALDR 
       310        320        330        340        350        360 
WAQFFIHPLM IRDAIDREVE AVDSEYQLAR PSDANRKEML FGSLARPGHP MGKFFWGNAE 
       370        380        390        400        410        420 
TLKHEPKKNN IDTHARLREF WMRYYSAHYM TLVVQSKETL DTLEKWVTEI FSQIPNNGLP 
       430        440        450        460        470        480 
KPNFSHLTDP FDTPAFNKLY RVVPIRKIHA LTITWALPPQ QQHYRVKPLH YISWLVGHEG 
       490        500        510        520        530        540 
KGSILSYLRK KCWALALFGG NGETGFEQNS TYSVFSISIT LTDEGYEHFY EVAHTVFQYL 
       550        560        570        580        590        600 
KMLQKLGPEK RVFEEIQKIE DNEFHYQEQT DPVEYVENMC ENMQLYPRQD FLTGDQLLFE 
       610        620        630        640        650        660 
YKPEVIAEAL NQLVPQKANL VLLSGANEGR CDLKEKWFGT QYSIEDIENS WTELWKSNFD 
       670        680        690        700        710        720 
LNPDLHLPAE NKYIATDFTL KAFDCPETEY PAKIVNTAQG CLWYKKDNKF KIPKAYIRFH 
       730        740        750        760        770        780 
LISPLIQKSA ANVVLFDIFV NILTHNLAEP AYEADVAQLE YKLVAGEHGL IIRVKGFNHK 
       790        800        810        820        830        840 
LPLLFQLIID YLTEFSSTPA VFTMITEQLK KTYFNILIKP ETLAKDVRLL ILEYSRWSMI 
       850        860        870        880        890        900 
DKYQALMDGL SLDSLLNFVK DFKSQLFVEG LVQGNVTSTE SMDFLKYVVD KLNFAPLERE 
       910        920        930        940        950        960 
MPVQFQVVEL PSGHHLCKVR ALNKGDANSE VTVYYQSGTR SLREYTLMEL LVMHMEEPCF 
       970        980        990       1000       1010       1020 
DFLRTKQTLG YHVYPTCRNT SGILGFSVTV GTQATKYNSE TVDKKIEEFL SSFEEKIENL 
      1030       1040       1050       1060       1070       1080 
TEDAFNTQVT ALIKLKECED THLGEEVDRN WNEVVTQQYL FDRLAHEIEA LKSFSKSDLV 
      1090       1100       1110       1120       1130       1140 
SWFKAHRGPG SKMLSVHVVG YGKYELEEDG APFGEDSNSR EGMQLTYLPP SPVLAESTTP 
      1150       1160    
ITDIRAFTAT LSLFPYHKIV K

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 1 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates