Q8BKC5: Importin-5

General Information

Protein names	- Importin-5 - Imp5 - Importin subunit beta-3 - Karyopherin beta-3 - Ran-binding protein 5 - RanBP5
Gene names	Ipo5
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8BKC5

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAAAAEQQQ FYLLLGNLLS PDNVVRKQAE ETYENIPGRS KITFLLQAIR NTTAAEEARQ
        70         80         90        100        110        120
MAAVLLRRLL SSAFDEVYPA LPSDVQTAIK SELLMIIQME TQSSMRKKIC DIAAELARNL
       130        140        150        160        170        180
IDEDGNNQWP EGLKFLFDSV SSQNMGLREA ALHIFWNFPG IFGNQQQHYL DVIKRMLVQC
       190        200        210        220        230        240
MQDQEHPSIR TLSARATAAF ILANEHNVAL FKHFADLLPG FLQAVNDSCY QNDDSVLKSL
       250        260        270        280        290        300
VEIADTVPKY LRPHLEATLQ LSLKLCGDTN LNNMQRQLAL EVIVTLSETA AAMLRKHTSL
       310        320        330        340        350        360
IAQTIPQMLA MMVDLEEDED WANADELEDD DFDSNAVAGE SALDRMACGL GGKLVLPMIK
       370        380        390        400        410        420
EHIMQMLQNP DWKYRHAGLM ALSAIGEGCH QQMEGILNEI VNFVLLFLQD PHPRVRYAAC
       430        440        450        460        470        480
NAVGQMATDF APGFQKKFHE KVIAALLQTM EDQGNQRVQA HAAAALINFT EDCPKSLLIP
       490        500        510        520        530        540
YLDNLVKHLH SIMVLKLQEL IQKGTKLVLE QVVTSIASVA DTAEEKFVPY YDLFMPSLKH
       550        560        570        580        590        600
IVENAVQKEL RLLRGKTIEC ISLIGLAVGK EKFMQDASDV MQLLLKTQTD FNDMEDDDPQ
       610        620        630        640        650        660
ISYMISAWAR MCKILGKEFQ QYLPVVMGPL MKTASIKPEV ALLDTQDMEN MSDDDGWEFV
       670        680        690        700        710        720
NLGDQQSFGI KTAGLEEKST ACQMLVCYAK ELKEGFVEYT EQVVKLMVPL LKFYFHDGVR
       730        740        750        760        770        780
VAAAESMPLL LECARVRGPE YLTQMWHFMC DALIKAIGTE PDSDVLSEIM HSFAKCIEVM
       790        800        810        820        830        840
GDGCLNNEHF EELGGILKAK LEEHFKNQEL RQVKRQDEDY DEQVEESLQD EDDNDVYILT
       850        860        870        880        890        900
KVSDILHSIF SSYKEKVLPW FEQLLPLIVN LICPQRPWPD RQWGLCIFDD IVEHCSPASF
       910        920        930        940        950        960
KYAEYFISPM LQYVCDNSPE VRQAAAYGLG VMAQFGGDNY RPFCTDALPL LVRVIQAPEA
       970        980        990       1000       1010       1020
KTKENVNATE NCISAVGKIM KFKPDCVNVE EVLPHWLSWL PLHEDKEEAV QTFSYLCDLI
      1030       1040       1050       1060       1070       1080
ESNHPIVLGP NNTNLPKIFS IIAEGEMHEA IKHEDPCAKR LANVVRQVQT SGGLWTECIA
      1090
QLSPEQQAAI QELLNSA

Isoforms

- Isoform 2 of Importin-5 - Isoform 2 of Importin-5

Sequence View

        10         20         30         40         50         60
MAAAAAEQQQ FYLLLGNLLS PDNVVRKQAE ETYENIPGRS KITFLLQAIR NTTAAEEARQ
        70         80         90        100        110        120
MAAVLLRRLL SSAFDEVYPA LPSDVQTAIK SELLMIIQME TQSSMRKKIC DIAAELARNL
       130        140        150        160        170        180
IDEDGNNQWP EGLKFLFDSV SSQNMGLREA ALHIFWNFPG IFGNQQQHYL DVIKRMLVQC
       190        200        210        220        230        240
MQDQEHPSIR TLSARATAAF ILANEHNVAL FKHFADLLPG FLQAVNDSCY QNDDSVLKSL
       250        260        270        280        290        300
VEIADTVPKY LRPHLEATLQ LSLKLCGDTN LNNMQRQLAL EVIVTLSETA AAMLRKHTSL
       310        320        330        340        350        360
IAQTIPQMLA MMVDLEEDED WANADELEDD DFDSNAVAGE SALDRMACGL GGKLVLPMIK
       370        380        390        400        410        420
EHIMQMLQNP DWKYRHAGLM ALSAIGEGCH QQMEGILNEI VNFVLLFLQD PHPRVRYAAC
       430        440        450        460        470        480
NAVGQMATDF APGFQKKFHE KVIAALLQTM EDQGNQRVQA HAAAALINFT EDCPKSLLIP
       490        500        510        520        530        540
YLDNLVKHLH SIMVLKLQEL IQKGTKLVLE QVVTSIASVA DTAEEKFVPY YDLFMPSLKH
       550        560        570        580        590        600
IVENAVQKEL RLLRGKTIEC ISLIGLAVGK EKFMQDASDV MQLLLKTQTD FNDMEDDDPQ
       610        620        630        640        650        660
ISYMISAWAR MCKILGKEFQ QYLPVVMGPL MKTASIKPEV ALLDTQDMEN MSDDDGWEFV
       670        680        690        700        710        720
NLGDQQSFGI KTAGLEEKST ACQMLVCYAK ELKEGFVEYT EQVVKLMVPL LKFYFHDGVR
       730        740        750        760        770        780
VAAAESMPLL LECARVRGPE YLTQMWHFMC DALIKAIGTE PDSDVLSEIM HSFAKCIEVM
       790        800        810        820        830        840
GDGCLNNEHF EELGGILKAK LEEHFKNQEL RQVKRQDEDY DEQVEESLQD EDDNDVYILT
       850        860        870        880        890        900
KVSDILHSIF SSYKEKVLPW FEQLLPLIVN LICPQRPWPD RQWGLCIFDD IVEHCSPASF
       910        920        930        940        950        960
KYAEYFISPM LQYVCDNSPE VRQAAAYGLG VMAQFGGDNY RPFCTDALPL LVRVIQAPEA
       970        980        990       1000       1010       1020
KTKENVNATE NCISAVGKIM KFKPDCVNVE EVLPHWLSWL PLHEDKEEAV QTFSYLCDLI
      1030       1040       1050       1060       1070       1080
ESNHPIVLGP NNTNLPKIFS IIAEGEMHEA IKHEDPCAKR LANVVRQVQT SGGLWTECIA
      1090
QLSPEQQAAI QELLNSA         10         20         30         40         50         60
MAAAAAEQQQ FYLLLGNLLS PDNVVRKQAE ETYENIPGRS KITFLLQAIR NTTAAEEARQ
        70         80         90        100        110        120
MAAVLLRRLL SSAFDEVYPA LPSDVQTAIK SELLMIIQME TQSSMRKKIC DIAAELARNL
       130        140        150        160        170        180
IDEDGNNQWP EGLKFLFDSV SSQNMGLREA ALHIFWNFPG IFGNQQQHYL DVIKRMLVQC
       190        200        210        220        230        240
MQDQEHPSIR TLSARATAAF ILANEHNVAL FKHFADLLPG FLQAVNDSCY QNDDSVLKSL
       250        260        270        280        290        300
VEIADTVPKY LRPHLEATLQ LSLKLCGDTN LNNMQRQLAL EVIVTLSETA AAMLRKHTSL
       310        320        330        340        350        360
IAQTIPQMLA MMVDLEEDED WANADELEDD DFDSNAVAGE SALDRMACGL GGKLVLPMIK
       370        380        390        400        410        420
EHIMQMLQNP DWKYRHAGLM ALSAIGEGCH QQMEGILNEI VNFVLLFLQD PHPRVRYAAC
       430        440        450        460        470        480
NAVGQMATDF APGFQKKFHE KVIAALLQTM EDQGNQRVQA HAAAALINFT EDCPKSLLIP
       490        500        510        520        530        540
YLDNLVKHLH SIMVLKLQEL IQKGTKLVLE QVVTSIASVA DTAEEKFVPY YDLFMPSLKH
       550        560        570        580        590        600
IVENAVQKEL RLLRGKTIEC ISLIGLAVGK EKFMQDASDV MQLLLKTQTD FNDMEDDDPQ
       610        620        630        640        650        660
ISYMISAWAR MCKILGKEFQ QYLPVVMGPL MKTASIKPEV ALLDTQDMEN MSDDDGWEFV
       670        680        690        700        710        720
NLGDQQSFGI KTAGLEEKST ACQMLVCYAK ELKEGFVEYT EQVVKLMVPL LKFYFHDGVR
       730        740        750        760        770        780
VAAAESMPLL LECARVRGPE YLTQMWHFMC DALIKAIGTE PDSDVLSEIM HSFAKCIEVM
       790        800        810        820        830        840
GDGCLNNEHF EELGGILKAK LEEHFKNQEL RQVKRQDEDY DEQVEESLQD EDDNDVYILT
       850        860        870        880        890        900
KVSDILHSIF SSYKEKVLPW FEQLLPLIVN LICPQRPWPD RQWGLCIFDD IVEHCSPASF
       910        920        930        940        950        960
KYAEYFISPM LQYVCDNSPE VRQAAAYGLG VMAQFGGDNY RPFCTDALPL LVRVIQAPEA
       970        980        990       1000       1010       1020
KTKENVNATE NCISAVGKIM KFKPDCVNVE EVLPHWLSWL PLHEDKEEAV QTFSYLCDLI
      1030       1040       1050       1060       1070       1080
ESNHPIVLGP NNTNLPKIFS IIAEGEMHEA IKHEDPCAKR LANVVRQVQT SGGLWTECIA
      1090
QLSPEQQAAI QELLNSA

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q8BKC5-2-unknown	MAAAAA...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q8BKC5-2-unknown	MAAAAA...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8BKC5-2-Acetylation	AAAAAE...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8BKC5-2-Acetylation	AAAAAE...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q8BKC5-18-unknown	LLSPDN...	18		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34080
Q8BKC5-232-unknown	NDDSVL...	232		inferred from electronic annotation	unknown	TISdb	inferred from TISdb
Q8BKC5-232-unknown	NDDSVL...	232		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt198327

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LLLGNL	17	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34080
...LLNSA	1097	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LLNSA	1097	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73630

TopFIND

Q8BKC5: Importin-5

General Information

4

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates