Q8BQ30: Phostensin

General Information

Protein names	- Phostensin - Protein phosphatase 1 F-actin cytoskeleton-targeting subunit - Protein phosphatase 1 regulatory subunit 18
Gene names	Ppp1r18
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8BQ30

4 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTAIPDWKLQ LLARRRQEEA AVRGREKAER DRLSQMPAWK RGILERRRAK LGLPPGEGSP
        70         80         90        100        110        120
VPGNAEAGPP DPDESAVLLE AIGPVHQNRF IQQERQRQQQ QQQQQRNEVL GDRKAGPLEV
       130        140        150        160        170        180
LERRSSPGNL RDQSPKGRES REERLSPRES RDRRLVIGGA QESSSRSLRD WRQSPAEARD
       190        200        210        220        230        240
LSSRPAEAQK WRLSPGETPE ESLRLAGSGD DSPKRKEVLE SILSPGEPGD QKASPTDVHK
       250        260        270        280        290        300
WNLDSREPQK QSLIQLEATE WRLKSGEERK DYLEGCGREE EKLSSGIVPV TKEVQDITSS
       310        320        330        340        350        360
EVETAEQRPT ESWKWTLNSG KARERTTWDI DTQTQKPDPP ASSEKHPGPS GMEAEEEAEK
       370        380        390        400        410        420
EEAEAQSRPL RAQQNLCSGP SPLPPEHSGT EGSRQQEEEA AEPRPPTPAP LSPPPSAPTA
       430        440        450        460        470        480
PQPSGDPLMS RLFYGVKPGP GVGAPRRSGH TFTVNPRRCA PPASPAPPVN PATADAAGSG
       490        500        510        520        530        540
SGKKRYPTAE EILVLGGYLR LSRSCLVKGS PERHHKQLKI SFSETALETT YQYPSESSVL
       550        560        570        580        590
EDLGPEPETP IAPLATQPDE EEEEEEEEEE LLLQPGLQGG LRTKALIVDE SCRR

Isoforms

- Isoform 2 of Phostensin

Sequence View

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Physiological Relevance:

Evidence Codes:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8BQ30-1-unknown	MTAIPD...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8BQ30-1-unknown	MTAIPD...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt86012
Q8BQ30-2-Acetylation	TAIPDW...	2	acetylation-		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
Q8BQ30-2-Acetylation	TAIPDW...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160764
Q8BQ30-571-unknown	LLLQPG...	571		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30734
Q8BQ30-572-unknown	LLQPGL...	572		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30736

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EEEEEL	570	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30734
...EEEEEL	570	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt137646
...EEEELL	571	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30736
...EEEELL	571	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt137652
...ESCRR	594	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	570	EEEL.\|.LLLQ	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PPR18_MOUSE @570
CATE_MOUSE	571	EELL.\|.LLQP	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PPR18_MOUSE @571

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)