Q8BQM4: HEAT repeat-containing protein 3

General Information

Protein names	- HEAT repeat-containing protein 3
Gene names	Heatr3
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8BQM4

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGKSRTKRFK RPQFSPIESC QAEAAAASNG TGDEEDDGPA AELLEKLQHP SAEVRECACA
        70         80         90        100        110        120
GLARLVQQRP ALPDLARRDA VRRLGPLLLD SSLAVRETAA GALRNLSACG GFDVCDDMVA
       130        140        150        160        170        180
KDIMTPLVAL LRECLSGLDS NEMSPQEKAD KRNPVESIAN EAVNVLWNVC ECSGRAVSIF
       190        200        210        220        230        240
NKEGCLEIVL QYLRRFPTSI DLAVSVAYCL QTVTEDNPEL LKSFDGTALR VLESALLCPV
       250        260        270        280        290        300
ASMEYILLKT LVAGTIWNLK DIIPSKSQAE IINAILGALS EVLGMNTGNM VIQMKEAETQ
       310        320        330        340        350        360
RLKTAAESED ILANANGDDL VEDDEMEEIP HKRKLRRKTF ISDLLPPTDK ELREAMALLT
       370        380        390        400        410        420
AQQTALEVIV NMCCSEDPSD DEWEELSSSD ESEAFMENSF SECSGHLMSP LCLSHEIHSA
       430        440        450        460        470        480
LTNCLIPEKV FEKTSSPNSV AVDICSKNPT WKPLIRKMNT IQCRALMCLQ SLVSLLDIDH
       490        500        510        520        530        540
LGGAPALQTL AQHLSQILFS QPDFAKHDDF LEAISSALRA LLQTMASKNI PQCMTPEQLM
       550        560        570        580        590        600
TLCREGIHSS SIGVRVNVVS ILGITGSVLA KDDGTLDTLK TIGCFLLEVA TKDPSLVVTG
       610        620        630        640        650        660
EALDALFDVF ADGEAAEKAS VQIKLLAALK EFQPVFKMKI RKEGRGKYSP DQLCVLDNVK
       670
MNLRRFIAYQ ETVEKRLTS

Isoforms

Sequence View

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q8BQM4-1-unknown	MGKSRT...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8BQM4-43-unknown	LLEKLQ...	43	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34082
Q8BQM4-118-unknown	MVAKDI...	118	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000112812
Q8BQM4-192-unknown	YLRRFP...	192	inferred from electronic annotation	unknown	TISdb	inferred from TISdb

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...GPAAEL	42	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34082
	...KRLTS	679	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	42	AAEL.\|.LLEK	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)