TopFIND 4.0

Q8IWU5: Extracellular sulfatase Sulf-2

General Information

Protein names
- Extracellular sulfatase Sulf-2
- hSulf-2
- 3.1.6.-
Gene names SULF2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8IWU5

3

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGPPSLVLCL LSATVFSLLG GSSAFLSHHR LKGRFQRDRR NIRPNIILVL TDDQDVELGS 
        70         80         90        100        110        120 
MQVMNKTRRI MEQGGAHFIN AFVTTPMCCP SRSSILTGKY VHNHNTYTNN ENCSSPSWQA 
       130        140        150        160        170        180 
QHESRTFAVY LNSTGYRTAF FGKYLNEYNG SYVPPGWKEW VGLLKNSRFY NYTLCRNGVK 
       190        200        210        220        230        240 
EKHGSDYSKD YLTDLITNDS VSFFRTSKKM YPHRPVLMVI SHAAPHGPED SAPQYSRLFP 
       250        260        270        280        290        300 
NASQHITPSY NYAPNPDKHW IMRYTGPMKP IHMEFTNMLQ RKRLQTLMSV DDSMETIYNM 
       310        320        330        340        350        360 
LVETGELDNT YIVYTADHGY HIGQFGLVKG KSMPYEFDIR VPFYVRGPNV EAGCLNPHIV 
       370        380        390        400        410        420 
LNIDLAPTIL DIAGLDIPAD MDGKSILKLL DTERPVNRFH LKKKMRVWRD SFLVERGKLL 
       430        440        450        460        470        480 
HKRDNDKVDA QEENFLPKYQ RVKDLCQRAE YQTACEQLGQ KWQCVEDATG KLKLHKCKGP 
       490        500        510        520        530        540 
MRLGGSRALS NLVPKYYGQG SEACTCDSGD YKLSLAGRRK KLFKKKYKAS YVRSRSIRSV 
       550        560        570        580        590        600 
AIEVDGRVYH VGLGDAAQPR NLTKRHWPGA PEDQDDKDGG DFSGTGGLPD YSAANPIKVT 
       610        620        630        640        650        660 
HRCYILENDT VQCDLDLYKS LQAWKDHKLH IDHEIETLQN KIKNLREVRG HLKKKRPEEC 
       670        680        690        700        710        720 
DCHKISYHTQ HKGRLKHRGS SLHPFRKGLQ EKDKVWLLRE QKRKKKLRKL LKRLQNNDTC 
       730        740        750        760        770        780 
SMPGLTCFTH DNQHWQTAPF WTLGPFCACT SANNNTYWCM RTINETHNFL FCEFATGFLE 
       790        800        810        820        830        840 
YFDLNTDPYQ LMNAVNTLDR DVLNQLHVQL MELRSCKGYK QCNPRTRNMD LGLKDGGSYE 
       850        860        870    
QYRQFQRRKW PEMKRPSSKS LGQLWEGWEG 

Isoforms

- Isoform 2 of Extracellular sulfatase Sulf-2

Sequence View

        10         20         30         40         50         60 
MGPPSLVLCL LSATVFSLLG GSSAFLSHHR LKGRFQRDRR NIRPNIILVL TDDQDVELGS 
        70         80         90        100        110        120 
MQVMNKTRRI MEQGGAHFIN AFVTTPMCCP SRSSILTGKY VHNHNTYTNN ENCSSPSWQA 
       130        140        150        160        170        180 
QHESRTFAVY LNSTGYRTAF FGKYLNEYNG SYVPPGWKEW VGLLKNSRFY NYTLCRNGVK 
       190        200        210        220        230        240 
EKHGSDYSKD YLTDLITNDS VSFFRTSKKM YPHRPVLMVI SHAAPHGPED SAPQYSRLFP 
       250        260        270        280        290        300 
NASQHITPSY NYAPNPDKHW IMRYTGPMKP IHMEFTNMLQ RKRLQTLMSV DDSMETIYNM 
       310        320        330        340        350        360 
LVETGELDNT YIVYTADHGY HIGQFGLVKG KSMPYEFDIR VPFYVRGPNV EAGCLNPHIV 
       370        380        390        400        410        420 
LNIDLAPTIL DIAGLDIPAD MDGKSILKLL DTERPVNRFH LKKKMRVWRD SFLVERGKLL 
       430        440        450        460        470        480 
HKRDNDKVDA QEENFLPKYQ RVKDLCQRAE YQTACEQLGQ KWQCVEDATG KLKLHKCKGP 
       490        500        510        520        530        540 
MRLGGSRALS NLVPKYYGQG SEACTCDSGD YKLSLAGRRK KLFKKKYKAS YVRSRSIRSV 
       550        560        570        580        590        600 
AIEVDGRVYH VGLGDAAQPR NLTKRHWPGA PEDQDDKDGG DFSGTGGLPD YSAANPIKVT 
       610        620        630        640        650        660 
HRCYILENDT VQCDLDLYKS LQAWKDHKLH IDHEIETLQN KIKNLREVRG HLKKKRPEEC 
       670        680        690        700        710        720 
DCHKISYHTQ HKGRLKHRGS SLHPFRKGLQ EKDKVWLLRE QKRKKKLRKL LKRLQNNDTC 
       730        740        750        760        770        780 
SMPGLTCFTH DNQHWQTAPF WTLGPFCACT SANNNTYWCM RTINETHNFL FCEFATGFLE 
       790        800        810        820        830        840 
YFDLNTDPYQ LMNAVNTLDR DVLNQLHVQL MELRSCKGYK QCNPRTRNMD LGLKDGGSYE 
       850        860        870    
QYRQFQRRKW PEMKRPSSKS LGQLWEGWEG 



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)