TopFIND 4.0

Q8IYW5: E3 ubiquitin-protein ligase RNF168 {ECO:0000255|HAMAP-Rule:MF_03066}

General Information

Protein names
- E3 ubiquitin-protein ligase RNF168 {ECO:0000255|HAMAP-Rule:MF_03066}
- hRNF168
- 2.3.2.27 {ECO:0000255|HAMAP-Rule:MF_03066}
- RING finger protein 168 {ECO:0000255|HAMAP-Rule:MF_03066}
- RING-type E3 ubiquitin transferase RNF168
Gene names RNF168
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8IYW5

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MALPKDAIPS LSECQCGICM EILVEPVTLP CNHTLCKPCF QSTVEKASLC CPFCRRRVSS 
        70         80         90        100        110        120 
WTRYHTRRNS LVNVELWTII QKHYPRECKL RASGQESEEV ADDYQPVRLL SKPGELRREY 
       130        140        150        160        170        180 
EEEISKVAAE RRASEEEENK ASEEYIQRLL AEEEEEEKRQ AEKRRRAMEE QLKSDEELAR 
       190        200        210        220        230        240 
KLSIDINNFC EGSISASPLN SRKSDPVTPK SEKKSKNKQR NTGDIQKYLT PKSQFGSASH 
       250        260        270        280        290        300 
SEAVQEVRKD SVSKDIDSSD RKSPTGQDTE IEDMPTLSPQ ISLGVGEQGA DSSIESPMPW 
       310        320        330        340        350        360 
LCACGAEWYH EGNVKTRPSN HGKELCVLSH ERPKTRVPYS KETAVMPCGR TESGCAPTSG 
       370        380        390        400        410        420 
VTQTNGNNTG ETENEESCLL ISKEISKRKN QESSFEAVKD PCFSAKRRKV SPESSPDQEE 
       430        440        450        460        470        480 
TEINFTQKLI DLEHLLFERH KQEEQDRLLA LQLQKEVDKE QMVPNRQKGS PDEYHLRATS 
       490        500        510        520        530        540 
SPPDKVLNGQ RKNPKDGNFK RQTHTKHPTP ERGSRDKNRQ VSLKMQLKQS VNRRKMPNST 
       550        560        570    
RDHCKVSKSA HSLQPSISQK SVFQMFQRCT K

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8IYW5-1-unknown MALPKD... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8IYW5-251- SVSKDI... 251 Subtiligase Based Positive Selection Wells apoptotic_Jurkat_staurotrail 23264352

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...QRCTK 571 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)