Q8JZX4: Splicing factor 45

General Information

Protein names	- Splicing factor 45 - 45 kDa-splicing factor - RNA-binding motif protein 17
Gene names	Rbm17
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8JZX4

3 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSLYDDLGVE TSDSKTEGWS KNFKLLQSQL QVKKAALTQA KSQRTKQSTV LAPVIDLKRG
        70         80         90        100        110        120
GSSDDRQIAD TPPHVAAGLK DPVPSGFSAG EVLIPLADEY DPMFPNDYEK VVKRQREERQ
       130        140        150        160        170        180
RQRELERQKE IEEREKRRKD RHEASGFSRR PDPDSDEDED YERERRKRSM GGAAIAPPTS
       190        200        210        220        230        240
LVEKDKELPR DFPYEEDSRP RSQSSKAAIP PPVYEEPDRP RSPTGPSNSF LANMGGTVAH
       250        260        270        280        290        300
KIMQKYGFRE GQGLGKHEQG LSTALSVEKT SKRGGKIIVG DATEKGEAQD ASKKSDSNPL
       310        320        330        340        350        360
TEILKCPTKV VLLRNMVGAG EVDEDLEVET KEECEKYGKV GKCVIFEIPG APDDEAVRIF
       370        380        390        400
LEFERVESAI KAVVDLNGRY FGGRVVKACF YNLDKFRVLD LAEQV

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q8JZX4-2-unknown	MSLYDD...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q8JZX4-2-unknown	MSLYDD...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8JZX4-2-Acetylation	SLYDDL...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8JZX4-2-Acetylation	SLYDDL...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q8JZX4-181-unknown	LVEKDK...	181		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34105

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RQREER	118	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000117133
...APPTSL	180	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34105
...LAEQV	405	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	180	PTSL.\|.LVEK	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)