Q8N806: Putative E3 ubiquitin-protein ligase UBR7

General Information

Protein names	- Putative E3 ubiquitin-protein ligase UBR7 - 2.3.2.27 - N-recognin-7 - RING-type E3 ubiquitin transferase UBR7
Gene names	UBR7
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8N806

4 N-termini

7 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAGAEGAAGR QSELEPVVSL VDVLEEDEEL ENEACAVLGG SDSEKCSYSQ GSVKRQALYA
        70         80         90        100        110        120
CSTCTPEGEE PAGICLACSY ECHGSHKLFE LYTKRNFRCD CGNSKFKNLE CKLLPDKAKV
       130        140        150        160        170        180
NSGNKYNDNF FGLYCICKRP YPDPEDEIPD EMIQCVVCED WFHGRHLGAI PPESGDFQEM
       190        200        210        220        230        240
VCQACMKRCS FLWAYAAQLA VTKISTEDDG LVRNIDGIGD QEVIKPENGE HQDSTLKEDV
       250        260        270        280        290        300
PEQGKDDVRE VKVEQNSEPC AGSSSESDLQ TVFKNESLNA ESKSGCKLQE LKAKQLIKKD
       310        320        330        340        350        360
TATYWPLNWR SKLCTCQDCM KMYGDLDVLF LTDEYDTVLA YENKGKIAQA TDRSDPLMDT
       370        380        390        400        410        420
LSSMNRVQQV ELICEYNDLK TELKDYLKRF ADEGTVVKRE DIQQFFEEFQ SKKRRRVDGM

QYYCS

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 7 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8N806-1-unknown	MAGAEG...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8N806-2-acetylation	AGAEGA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q8N806-234-	STLKED...	234			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q8N806-337-unknown	TVLAYE...	337		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2272

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...AIPPES	173	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000451051
...TEDDGL	210	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000450645
...KDDVRE	249	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000451022
...TDEYDT	336	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2272
...DGMQYY	422	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000451785
...QYYCS	425		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...QYYCS	425		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...QYYCS	425	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...QYYCS	425		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...QYYCS	425		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP3_HUMAN	336	EYDT.\|.TVLA	inferred from experiment	unknown	MEROPS		Merops CASP3_HUMAN -> UBR7_HUMAN @336

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)