Q8NCE2: Myotubularin-related protein 14

General Information

Protein names	- Myotubularin-related protein 14 - 3.1.3.- - HCV NS5A-transactivated protein 4 splice variant A-binding protein 1 - NS5ATP4ABP1 - hJumpy
Gene names	MTMR14
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8NCE2

2 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Myotubularin-related protein 14 - Isoform 3 of Myotubularin-related protein 14

Sequence View

        10         20         30         40         50         60
MAGARAAAAA ASAGSSASSG NQPPQELGLG ELLEEFSRTQ YRAKDGSGTG GSKVERIEKR
        70         80         90        100        110        120
CLELFGRDYC FSVIPNTNGD ICGHYPRHIV FLEYESSEKE KDTFESTVQV SKLQDLIHRS
       130        140        150        160        170        180
KMARCRGRFV CPVILFKGKH ICRSATLAGW GELYGRSGYN YFFSGGADDA WADVEDVTEE
       190        200        210        220        230        240
DCALRSGDTH LFDKVRGYDI KLLRYLSVKY ICDLMVENKK VKFGMNVTSS EKVDKAQRYA
       250        260        270        280        290        300
DFTLLSIPYP GCEFFKEYKD RDYMAEGLIF NWKQDYVDAP LSIPDFLTHS LNIDWSQYQC
       310        320        330        340        350        360
WDLVQQTQNY LKLLLSLVNS DDDSGLLVHC ISGWDRTPLF ISLLRLSLWA DGLIHTSLKP
       370        380        390        400        410        420
TEILYLTVAY DWFLFGHMLV DRLSKGEEIF FFCFNFLKHI TSEEFSALKT QRRKSLPARD
       430        440        450        460        470        480
GGFTLEDICM LRRKDRGSTT SLGSDFSLVM ESSPGATGSF TYEAVELVPA GAPTQAAWRK
       490        500        510        520        530        540
SHSSSPQSVL WNRPQPSEDR LPSQQGLAEA RSSSSSSSNH SDNFFRMGSS PLEVPKPRSV
       550        560        570        580        590        600
DHPLPGSSLS TDYGSWQMVT GCGSIQERAV LHTDSSLPFS FPDELPNSCL LAALSDRETR
       610        620        630        640        650
LQEVRSAFLA AYSSTVGLRA VAPSPSGAIG GLLEQFARGV GLRSISSNAL         10         20         30         40         50         60
MAGARAAAAA ASAGSSASSG NQPPQELGLG ELLEEFSRTQ YRAKDGSGTG GSKVERIEKR
        70         80         90        100        110        120
CLELFGRDYC FSVIPNTNGD ICGHYPRHIV FLEYESSEKE KDTFESTVQV SKLQDLIHRS
       130        140        150        160        170        180
KMARCRGRFV CPVILFKGKH ICRSATLAGW GELYGRSGYN YFFSGGADDA WADVEDVTEE
       190        200        210        220        230        240
DCALRSGDTH LFDKVRGYDI KLLRYLSVKY ICDLMVENKK VKFGMNVTSS EKVDKAQRYA
       250        260        270        280        290        300
DFTLLSIPYP GCEFFKEYKD RDYMAEGLIF NWKQDYVDAP LSIPDFLTHS LNIDWSQYQC
       310        320        330        340        350        360
WDLVQQTQNY LKLLLSLVNS DDDSGLLVHC ISGWDRTPLF ISLLRLSLWA DGLIHTSLKP
       370        380        390        400        410        420
TEILYLTVAY DWFLFGHMLV DRLSKGEEIF FFCFNFLKHI TSEEFSALKT QRRKSLPARD
       430        440        450        460        470        480
GGFTLEDICM LRRKDRGSTT SLGSDFSLVM ESSPGATGSF TYEAVELVPA GAPTQAAWRK
       490        500        510        520        530        540
SHSSSPQSVL WNRPQPSEDR LPSQQGLAEA RSSSSSSSNH SDNFFRMGSS PLEVPKPRSV
       550        560        570        580        590        600
DHPLPGSSLS TDYGSWQMVT GCGSIQERAV LHTDSSLPFS FPDELPNSCL LAALSDRETR
       610        620        630        640        650
LQEVRSAFLA AYSSTVGLRA VAPSPSGAIG GLLEQFARGV GLRSISSNAL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q8NCE2-1-unknown	MAGARA...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8NCE2-1-unknown	MAGARA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81769
Q8NCE2-1-unknown	MAGARA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81770
Q8NCE2-346-unknown	LSLWAD...	346	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19715
Q8NCE2-346-unknown	LSLWAD...	346	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt150863
Q8NCE2-346-unknown	LSLWAD...	346	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt150864

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ISLLRL	345	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19715
...ISLLRL	345	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134264
...ISLLRL	345	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134265
...SSNAL	650	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SSNAL	650	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt77388
...SSNAL	650	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt77387

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	345	LLRL.\|.LSLW	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)