Q8TB72: Pumilio homolog 2

General Information

Protein names	- Pumilio homolog 2 - Pumilio-2
Gene names	PUM2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8TB72

7 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Pumilio homolog 2 - Isoform 3 of Pumilio homolog 2 - Isoform 4 of Pumilio homolog 2

Sequence View

        10         20         30         40         50         60
MNHDFQALAL ESRGMGELLP TKKFWEPDDS TKDGQKGIFL GDDEWRETAW GASHHSMSQP
        70         80         90        100        110        120
IMVQRRSGQG FHGNSEVNAI LSPRSESGGL GVSMVEYVLS SSPADKLDSR FRKGNFGTRD
       130        140        150        160        170        180
AETDGPEKGD QKGKASPFEE DQNRDLKQGD DDDSKINGRG LPNGMDADCK DFNRTPGSRQ
       190        200        210        220        230        240
ASPTEVVERL GPNTNPSEGL GPLPNPTANK PLVEEFSNPE TQNLDAMEQV GLESLQFDYP
       250        260        270        280        290        300
GNQVPMDSSG ATVGLFDYNS QQQLFQRTNA LTVQQLTAAQ QQQYALAAAQ QPHIAGVFSA
       310        320        330        340        350        360
GLAPAAFVPN PYIISAAPPG TDPYTAAGLA AAATLAGPAV VPPQYYGVPW GVYPANLFQQ
       370        380        390        400        410        420
QAAAAANNTA SQQAASQAQP GQQQVLRAGA GQRPLTPNQG QQGQQAESLA AAAAANPTLA
       430        440        450        460        470        480
FGQGLATGMP GYQVLAPTAY YDQTGALVVG PGARTGLGAP VRLMAPTPVL ISSAAAQAAA
       490        500        510        520        530        540
AAAAGGTASS LTGSTNGLFR PIGTQPPQQQ QQQPSTNLQS NSFYGSSSLT NSSQSSSLFS
       550        560        570        580        590        600
HGPGQPGSTS LGFGSGNSLG AAIGSALSGF GSSVGSSASS SATRRESLST SSDLYKRSSS
       610        620        630        640        650        660
SLAPIGQPFY NSLGFSSSPS PIGMPLPSQT PGHSLTPPPS LSSHGSSSSL HLGGLTNGSG
       670        680        690        700        710        720
RYISAAPGAE AKYRSASSTS SLFSSSSQLF PPSRLRYNRS DIMPSGRSRL LEDFRNNRFP
       730        740        750        760        770        780
NLQLRDLIGH IVEFSQDQHG SRFIQQKLER ATPAERQMVF NEILQAAYQL MTDVFGNYVI
       790        800        810        820        830        840
QKFFEFGSLD QKLALATRIR GHVLPLALQM YGCRVIQKAL ESISSDQQVI SEMVKELDGH
       850        860        870        880        890        900
VLKCVKDQNG NHVVQKCIEC VQPQSLQFII DAFKGQVFVL STHPYGCRVI QRILEHCTAE
       910        920        930        940        950        960
QTLPILEELH QHTEQLVQDQ YGNYVIQHVL EHGRPEDKSK IVSEIRGKVL ALSQHKFASN
       970        980        990       1000       1010       1020
VVEKCVTHAS RAERALLIDE VCCQNDGPHS ALYTMMKDQY ANYVVQKMID MAEPAQRKII
      1030       1040       1050       1060
MHKIRPHITT LRKYTYGKHI LAKLEKYYLK NSPDLGPIGG PPNGML         10         20         30         40         50         60
MNHDFQALAL ESRGMGELLP TKKFWEPDDS TKDGQKGIFL GDDEWRETAW GASHHSMSQP
        70         80         90        100        110        120
IMVQRRSGQG FHGNSEVNAI LSPRSESGGL GVSMVEYVLS SSPADKLDSR FRKGNFGTRD
       130        140        150        160        170        180
AETDGPEKGD QKGKASPFEE DQNRDLKQGD DDDSKINGRG LPNGMDADCK DFNRTPGSRQ
       190        200        210        220        230        240
ASPTEVVERL GPNTNPSEGL GPLPNPTANK PLVEEFSNPE TQNLDAMEQV GLESLQFDYP
       250        260        270        280        290        300
GNQVPMDSSG ATVGLFDYNS QQQLFQRTNA LTVQQLTAAQ QQQYALAAAQ QPHIAGVFSA
       310        320        330        340        350        360
GLAPAAFVPN PYIISAAPPG TDPYTAAGLA AAATLAGPAV VPPQYYGVPW GVYPANLFQQ
       370        380        390        400        410        420
QAAAAANNTA SQQAASQAQP GQQQVLRAGA GQRPLTPNQG QQGQQAESLA AAAAANPTLA
       430        440        450        460        470        480
FGQGLATGMP GYQVLAPTAY YDQTGALVVG PGARTGLGAP VRLMAPTPVL ISSAAAQAAA
       490        500        510        520        530        540
AAAAGGTASS LTGSTNGLFR PIGTQPPQQQ QQQPSTNLQS NSFYGSSSLT NSSQSSSLFS
       550        560        570        580        590        600
HGPGQPGSTS LGFGSGNSLG AAIGSALSGF GSSVGSSASS SATRRESLST SSDLYKRSSS
       610        620        630        640        650        660
SLAPIGQPFY NSLGFSSSPS PIGMPLPSQT PGHSLTPPPS LSSHGSSSSL HLGGLTNGSG
       670        680        690        700        710        720
RYISAAPGAE AKYRSASSTS SLFSSSSQLF PPSRLRYNRS DIMPSGRSRL LEDFRNNRFP
       730        740        750        760        770        780
NLQLRDLIGH IVEFSQDQHG SRFIQQKLER ATPAERQMVF NEILQAAYQL MTDVFGNYVI
       790        800        810        820        830        840
QKFFEFGSLD QKLALATRIR GHVLPLALQM YGCRVIQKAL ESISSDQQVI SEMVKELDGH
       850        860        870        880        890        900
VLKCVKDQNG NHVVQKCIEC VQPQSLQFII DAFKGQVFVL STHPYGCRVI QRILEHCTAE
       910        920        930        940        950        960
QTLPILEELH QHTEQLVQDQ YGNYVIQHVL EHGRPEDKSK IVSEIRGKVL ALSQHKFASN
       970        980        990       1000       1010       1020
VVEKCVTHAS RAERALLIDE VCCQNDGPHS ALYTMMKDQY ANYVVQKMID MAEPAQRKII
      1030       1040       1050       1060
MHKIRPHITT LRKYTYGKHI LAKLEKYYLK NSPDLGPIGG PPNGML         10         20         30         40         50         60
MNHDFQALAL ESRGMGELLP TKKFWEPDDS TKDGQKGIFL GDDEWRETAW GASHHSMSQP
        70         80         90        100        110        120
IMVQRRSGQG FHGNSEVNAI LSPRSESGGL GVSMVEYVLS SSPADKLDSR FRKGNFGTRD
       130        140        150        160        170        180
AETDGPEKGD QKGKASPFEE DQNRDLKQGD DDDSKINGRG LPNGMDADCK DFNRTPGSRQ
       190        200        210        220        230        240
ASPTEVVERL GPNTNPSEGL GPLPNPTANK PLVEEFSNPE TQNLDAMEQV GLESLQFDYP
       250        260        270        280        290        300
GNQVPMDSSG ATVGLFDYNS QQQLFQRTNA LTVQQLTAAQ QQQYALAAAQ QPHIAGVFSA
       310        320        330        340        350        360
GLAPAAFVPN PYIISAAPPG TDPYTAAGLA AAATLAGPAV VPPQYYGVPW GVYPANLFQQ
       370        380        390        400        410        420
QAAAAANNTA SQQAASQAQP GQQQVLRAGA GQRPLTPNQG QQGQQAESLA AAAAANPTLA
       430        440        450        460        470        480
FGQGLATGMP GYQVLAPTAY YDQTGALVVG PGARTGLGAP VRLMAPTPVL ISSAAAQAAA
       490        500        510        520        530        540
AAAAGGTASS LTGSTNGLFR PIGTQPPQQQ QQQPSTNLQS NSFYGSSSLT NSSQSSSLFS
       550        560        570        580        590        600
HGPGQPGSTS LGFGSGNSLG AAIGSALSGF GSSVGSSASS SATRRESLST SSDLYKRSSS
       610        620        630        640        650        660
SLAPIGQPFY NSLGFSSSPS PIGMPLPSQT PGHSLTPPPS LSSHGSSSSL HLGGLTNGSG
       670        680        690        700        710        720
RYISAAPGAE AKYRSASSTS SLFSSSSQLF PPSRLRYNRS DIMPSGRSRL LEDFRNNRFP
       730        740        750        760        770        780
NLQLRDLIGH IVEFSQDQHG SRFIQQKLER ATPAERQMVF NEILQAAYQL MTDVFGNYVI
       790        800        810        820        830        840
QKFFEFGSLD QKLALATRIR GHVLPLALQM YGCRVIQKAL ESISSDQQVI SEMVKELDGH
       850        860        870        880        890        900
VLKCVKDQNG NHVVQKCIEC VQPQSLQFII DAFKGQVFVL STHPYGCRVI QRILEHCTAE
       910        920        930        940        950        960
QTLPILEELH QHTEQLVQDQ YGNYVIQHVL EHGRPEDKSK IVSEIRGKVL ALSQHKFASN
       970        980        990       1000       1010       1020
VVEKCVTHAS RAERALLIDE VCCQNDGPHS ALYTMMKDQY ANYVVQKMID MAEPAQRKII
      1030       1040       1050       1060
MHKIRPHITT LRKYTYGKHI LAKLEKYYLK NSPDLGPIGG PPNGML

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8TB72-1-unknown	MNHDFQ...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8TB72-1-unknown	MNHDFQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt86657
Q8TB72-1-unknown	MNHDFQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt86658
Q8TB72-57-unknown	MSQPIM...	57	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt86659
Q8TB72-57-unknown	MSQPIM...	57	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000440093
Q8TB72-57-unknown	MSQPIM...	57	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt103319
Q8TB72-57-unknown	MSQPIM...	57	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt103320
Q8TB72-110-unknown	RFRKGN...	110	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000409905
Q8TB72-110-unknown	RFRKGN...	110	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt197097
Q8TB72-110-unknown	RFRKGN...	110	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt197098
Q8TB72-110-unknown	RFRKGN...	110	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt197099
Q8TB72-241-	GNQVPM...	241		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q8TB72-241-unknown	GNQVPM...	241	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171271
Q8TB72-241-unknown	GNQVPM...	241	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171272
Q8TB72-241-unknown	GNQVPM...	241	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171273
Q8TB72-363-	AAAANN...	363		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q8TB72-363-unknown	AAAANN...	363	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174024
Q8TB72-363-unknown	AAAANN...	363	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174025
Q8TB72-363-unknown	AAAANN...	363	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174026

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...STKDGQ	34	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000395098
...STKDGQ	34	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153768
...STKDGQ	34	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153769
...AQQPHI	293	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000387399
...PNGML	1066	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...PNGML	1066	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82275
...PNGML	1066	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82277
...PNGML	1066	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82276

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)