Q8TE59: A disintegrin and metalloproteinase with thrombospondin motifs 19
Protein names | - A disintegrin and metalloproteinase with thrombospondin motifs 19 - ADAM-TS 19 - ADAM-TS19 - ADAMTS-19 - 3.4.24.- |
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Gene names | ADAMTS19 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | M12.029 |
Chromosome location | |
UniProt ID | Q8TE59 |
3
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MRLTHICCCC LLYQLGFLSN GIVSELQFAP DREEWEVVFP ALWRREPVDP AGGSGGSADP
70 80 90 100 110 120
GWVRGVGGGG SARAQAAGSS REVRSVAPVP LEEPVEGRSE SRLRPPPPSE GEEDEELESQ
130 140 150 160 170 180
ELPRGSSGAA ALSPGAPASW QPPPPPQPPP SPPPAQHAEP DGDEVLLRIP AFSRDLYLLL
190 200 210 220 230 240
RRDGRFLAPR FAVEQRPNPG PGPTGAASAP QPPAPPDAGC FYTGAVLRHP GSLASFSTCG
250 260 270 280 290 300
GGLMGFIQLN EDFIFIEPLN DTMAITGHPH RVYRQKRSME EKVTEKSALH SHYCGIISDK
310 320 330 340 350 360
GRPRSRKIAE SGRGKRYSYK LPQEYNIETV VVADPAMVSY HGADAARRFI LTILNMVFNL
370 380 390 400 410 420
FQHKSLSVQV NLRVIKLILL HETPPELYIG HHGEKMLESF CKWQHEEFGK KNDIHLEMST
430 440 450 460 470 480
NWGEDMTSVD AAILITRKDF CVHKDEPCDT VGIAYLSGMC SEKRKCIIAE DNGLNLAFTI
490 500 510 520 530 540
AHEMGHNMGI NHDNDHPSCA DGLHIMSGEW IKGQNLGDVS WSRCSKEDLE RFLRSKASNC
550 560 570 580 590 600
LLQTNPQSVN SVMVPSKLPG MTYTADEQCQ ILFGPLASFC QEMQHVICTG LWCKVEGEKE
610 620 630 640 650 660
CRTKLDPPMD GTDCDLGKWC KAGECTSRTS APEHLAGEWS LWSPCSRTCS AGISSRERKC
670 680 690 700 710 720
PGLDSEARDC NGPRKQYRIC ENPPCPAGLP GFRDWQCQAY SVRTSSPKHI LQWQAVLDEE
730 740 750 760 770 780
KPCALFCSPV GKEQPILLSE KVMDGTSCGY QGLDICANGR CQKVGCDGLL GSLAREDHCG
790 800 810 820 830 840
VCNGNGKSCK IIKGDFNHTR GAGYVEVLVI PAGARRIKVV EEKPAHSYLA LRDAGKQSIN
850 860 870 880 890 900
SDWKIEHSGA FNLAGTTVHY VRRGLWEKIS AKGPTTAPLH LLVLLFQDQN YGLHYEYTIP
910 920 930 940 950 960
SDPLPENQSS KAPEPLFMWT HTSWEDCDAT CGGGERKTTV SCTKIMSKNI SIVDNEKCKY
970 980 990 1000 1010 1020
LTKPEPQIRK CNEQPCQTRW MMTEWTPCSR TCGKGMQSRQ VACTQQLSNG TLIRARERDC
1030 1040 1050 1060 1070 1080
IGPKPASAQR CEGQDCMTVW EAGVWSECSV KCGKGIRHRT VRCTNPRKKC VLSTRPREAE
1090 1100 1110 1120 1130 1140
DCEDYSKCYV WRMGDWSKCS ITCGKGMQSR VIQCMHKITG RHGNECFSSE KPAAYRPCHL
1150 1160 1170 1180 1190 1200
QPCNEKINVN TITSPRLAAL TFKCLGDQWP VYCRVIREKN LCQDMRWYQR CCETCRDFYA
QKLQQKS
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q8TE59-22-unknown | IVSELQ... | 22 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q8TE59-213-unknown | PAPPDA... | 213 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6596 | |||
Q8TE59-317-unknown | YSYKLP... | 317 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q8TE59-317-unknown | YSYKLP... | 317 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...SAPQPP | 212 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6596 | |||
...LQQKS | 1207 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATL1_HUMAN | 212 | PQPP.|.PAPP | inferred from experiment | unknown | MEROPS | Schilling O | Biniossek ML et al.:Proteomic identification of pro... (C01.060) | 21967108, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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