Q8TF40: Folliculin-interacting protein 1

General Information

Protein names	- Folliculin-interacting protein 1
Gene names	FNIP1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8TF40

2 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAPTLFQKLF SKRTGLGAPG RDARDPDCGF SWPLPEFDPS QIRLIVYQDC ERRGRNVLFD
        70         80         90        100        110        120
SSVKRRNEDI SVSKLGSDAQ VKVFGKCCQL KPGGDSSSSL DSSVTSSSDI KDQCLKYQGS
       130        140        150        160        170        180
RCSSDANMLG EMMFGSVAMS YKGSTLKIHQ IRSPPQLMLS KVFTARTGSS ICGSLNTLQD
       190        200        210        220        230        240
SLEFINQDNN TLKADNNTVI NGLLGNIGLS QFCSPRRAFS EQGPLRLIRS ASFFAVHSNP
       250        260        270        280        290        300
MDMPGRELNE DRDSGIARSA SLSSLLITPF PSPNSSLTRS CASSYQRRWR RSQTTSLENG
       310        320        330        340        350        360
VFPRWSIEES FNLSDESCGP NPGIVRKKKI AIGVIFSLSK DEDENNKFNE FFFSHFPLFE
       370        380        390        400        410        420
SHMNKLKSAI EQAMKMSRRS ADASQRSLAY NRIVDALNEF RTTICNLYTM PRIGEPVWLT
       430        440        450        460        470        480
MMSGTPEKNH LCYRFMKEFT FLMENASKNQ FLPALITAVL TNHLAWVPTV MPNGQPPIKI
       490        500        510        520        530        540
FLEKHSSQSV DMLAKTHPYN PLWAQLGDLY GAIGSPVRLA RTVVVGKRQD MVQRLLYFLT
       550        560        570        580        590        600
YFIRCSELQE THLLENGEDE AIVMPGTVIT TTLEKGEIEE SEYVLVTMHR NKSSLLFKES
       610        620        630        640        650        660
EEIRTPNCNC KYCSHPLLGQ NVENISQQER EDIQNSSKEL LGISDECQMI SPSDCQEENA
       670        680        690        700        710        720
VDVKQYRDKL RTCFDAKLET VVCTGSVPVD KCALSESGLE STEETWQSEK LLDSDSHTGK
       730        740        750        760        770        780
AMRSTGMVVE KKPPDKIVPA SFSCEAAQTK VTFLIGDSMS PDSDTELRSQ AVVDQITRHH
       790        800        810        820        830        840
TKPLKEERGA IDQHQETKQT TKDQSGESDT QNMVSEEPCE LPCWNHSDPE SMSLFDEYFN
       850        860        870        880        890        900
DDSIETRTID DVPFKTSTDS KDHCCMLEFS KILCTKNNKQ NNEFCKCIET VPQDSCKTCF
       910        920        930        940        950        960
PQQDQRDTLS ILVPHGDKES SDKKIAVGTE WDIPRNESSD SALGDSESED TGHDMTRQVS
       970        980        990       1000       1010       1020
SYYGGEQEDW AEEDEIPFPG SKLIEVSAVQ PNIANFGRSL LGGYCSSYVP DFVLQGIGSD
      1030       1040       1050       1060       1070       1080
ERFRQCLMSD LSHAVQHPVL DEPIAEAVCI IADMDKWTVQ VASSQRRVTD NKLGKEVLVS
      1090       1100       1110       1120       1130       1140
SLVSNLLHST LQLYKHNLSP NFCVMHLEDR LQELYFKSKM LSEYLRGQMR VHVKELGVVL
      1150       1160
GIESSDLPLL AAVASTHSPY VAQILL

Isoforms

- Isoform 2 of Folliculin-interacting protein 1 - Isoform 3 of Folliculin-interacting protein 1

Sequence View

        10         20         30         40         50         60
MAPTLFQKLF SKRTGLGAPG RDARDPDCGF SWPLPEFDPS QIRLIVYQDC ERRGRNVLFD
        70         80         90        100        110        120
SSVKRRNEDI SVSKLGSDAQ VKVFGKCCQL KPGGDSSSSL DSSVTSSSDI KDQCLKYQGS
       130        140        150        160        170        180
RCSSDANMLG EMMFGSVAMS YKGSTLKIHQ IRSPPQLMLS KVFTARTGSS ICGSLNTLQD
       190        200        210        220        230        240
SLEFINQDNN TLKADNNTVI NGLLGNIGLS QFCSPRRAFS EQGPLRLIRS ASFFAVHSNP
       250        260        270        280        290        300
MDMPGRELNE DRDSGIARSA SLSSLLITPF PSPNSSLTRS CASSYQRRWR RSQTTSLENG
       310        320        330        340        350        360
VFPRWSIEES FNLSDESCGP NPGIVRKKKI AIGVIFSLSK DEDENNKFNE FFFSHFPLFE
       370        380        390        400        410        420
SHMNKLKSAI EQAMKMSRRS ADASQRSLAY NRIVDALNEF RTTICNLYTM PRIGEPVWLT
       430        440        450        460        470        480
MMSGTPEKNH LCYRFMKEFT FLMENASKNQ FLPALITAVL TNHLAWVPTV MPNGQPPIKI
       490        500        510        520        530        540
FLEKHSSQSV DMLAKTHPYN PLWAQLGDLY GAIGSPVRLA RTVVVGKRQD MVQRLLYFLT
       550        560        570        580        590        600
YFIRCSELQE THLLENGEDE AIVMPGTVIT TTLEKGEIEE SEYVLVTMHR NKSSLLFKES
       610        620        630        640        650        660
EEIRTPNCNC KYCSHPLLGQ NVENISQQER EDIQNSSKEL LGISDECQMI SPSDCQEENA
       670        680        690        700        710        720
VDVKQYRDKL RTCFDAKLET VVCTGSVPVD KCALSESGLE STEETWQSEK LLDSDSHTGK
       730        740        750        760        770        780
AMRSTGMVVE KKPPDKIVPA SFSCEAAQTK VTFLIGDSMS PDSDTELRSQ AVVDQITRHH
       790        800        810        820        830        840
TKPLKEERGA IDQHQETKQT TKDQSGESDT QNMVSEEPCE LPCWNHSDPE SMSLFDEYFN
       850        860        870        880        890        900
DDSIETRTID DVPFKTSTDS KDHCCMLEFS KILCTKNNKQ NNEFCKCIET VPQDSCKTCF
       910        920        930        940        950        960
PQQDQRDTLS ILVPHGDKES SDKKIAVGTE WDIPRNESSD SALGDSESED TGHDMTRQVS
       970        980        990       1000       1010       1020
SYYGGEQEDW AEEDEIPFPG SKLIEVSAVQ PNIANFGRSL LGGYCSSYVP DFVLQGIGSD
      1030       1040       1050       1060       1070       1080
ERFRQCLMSD LSHAVQHPVL DEPIAEAVCI IADMDKWTVQ VASSQRRVTD NKLGKEVLVS
      1090       1100       1110       1120       1130       1140
SLVSNLLHST LQLYKHNLSP NFCVMHLEDR LQELYFKSKM LSEYLRGQMR VHVKELGVVL
      1150       1160
GIESSDLPLL AAVASTHSPY VAQILL         10         20         30         40         50         60
MAPTLFQKLF SKRTGLGAPG RDARDPDCGF SWPLPEFDPS QIRLIVYQDC ERRGRNVLFD
        70         80         90        100        110        120
SSVKRRNEDI SVSKLGSDAQ VKVFGKCCQL KPGGDSSSSL DSSVTSSSDI KDQCLKYQGS
       130        140        150        160        170        180
RCSSDANMLG EMMFGSVAMS YKGSTLKIHQ IRSPPQLMLS KVFTARTGSS ICGSLNTLQD
       190        200        210        220        230        240
SLEFINQDNN TLKADNNTVI NGLLGNIGLS QFCSPRRAFS EQGPLRLIRS ASFFAVHSNP
       250        260        270        280        290        300
MDMPGRELNE DRDSGIARSA SLSSLLITPF PSPNSSLTRS CASSYQRRWR RSQTTSLENG
       310        320        330        340        350        360
VFPRWSIEES FNLSDESCGP NPGIVRKKKI AIGVIFSLSK DEDENNKFNE FFFSHFPLFE
       370        380        390        400        410        420
SHMNKLKSAI EQAMKMSRRS ADASQRSLAY NRIVDALNEF RTTICNLYTM PRIGEPVWLT
       430        440        450        460        470        480
MMSGTPEKNH LCYRFMKEFT FLMENASKNQ FLPALITAVL TNHLAWVPTV MPNGQPPIKI
       490        500        510        520        530        540
FLEKHSSQSV DMLAKTHPYN PLWAQLGDLY GAIGSPVRLA RTVVVGKRQD MVQRLLYFLT
       550        560        570        580        590        600
YFIRCSELQE THLLENGEDE AIVMPGTVIT TTLEKGEIEE SEYVLVTMHR NKSSLLFKES
       610        620        630        640        650        660
EEIRTPNCNC KYCSHPLLGQ NVENISQQER EDIQNSSKEL LGISDECQMI SPSDCQEENA
       670        680        690        700        710        720
VDVKQYRDKL RTCFDAKLET VVCTGSVPVD KCALSESGLE STEETWQSEK LLDSDSHTGK
       730        740        750        760        770        780
AMRSTGMVVE KKPPDKIVPA SFSCEAAQTK VTFLIGDSMS PDSDTELRSQ AVVDQITRHH
       790        800        810        820        830        840
TKPLKEERGA IDQHQETKQT TKDQSGESDT QNMVSEEPCE LPCWNHSDPE SMSLFDEYFN
       850        860        870        880        890        900
DDSIETRTID DVPFKTSTDS KDHCCMLEFS KILCTKNNKQ NNEFCKCIET VPQDSCKTCF
       910        920        930        940        950        960
PQQDQRDTLS ILVPHGDKES SDKKIAVGTE WDIPRNESSD SALGDSESED TGHDMTRQVS
       970        980        990       1000       1010       1020
SYYGGEQEDW AEEDEIPFPG SKLIEVSAVQ PNIANFGRSL LGGYCSSYVP DFVLQGIGSD
      1030       1040       1050       1060       1070       1080
ERFRQCLMSD LSHAVQHPVL DEPIAEAVCI IADMDKWTVQ VASSQRRVTD NKLGKEVLVS
      1090       1100       1110       1120       1130       1140
SLVSNLLHST LQLYKHNLSP NFCVMHLEDR LQELYFKSKM LSEYLRGQMR VHVKELGVVL
      1150       1160
GIESSDLPLL AAVASTHSPY VAQILL

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q8TF40-1-unknown	MAPTLF...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8TF40-1-unknown	MAPTLF...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75343
Q8TF40-1-unknown	MAPTLF...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75344
Q8TF40-93-unknown	GGDSSS...	93	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6598
Q8TF40-93-unknown	GGDSSS...	93	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt142041
Q8TF40-93-unknown	GGDSSS...	93	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt142042

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...CQLKPG	92	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6598
...CQLKPG	92	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125224
...CQLKPG	92	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125225
...AQILL	1166	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...AQILL	1166	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt70962

TopFIND

Q8TF40: Folliculin-interacting protein 1

General Information

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates