TopFIND 4.0

Q8VBW6: NEDD8-activating enzyme E1 regulatory subunit

General Information

Protein names
- NEDD8-activating enzyme E1 regulatory subunit
- Amyloid beta precursor protein-binding protein 1, 59 kDa
- APP-BP1
- Amyloid protein-binding protein 1

Gene names Nae1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8VBW6

4

N-termini

3

C-termini

2

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAQPGKILKE QKYDRQLRLW GDHGQEALES AHVCLINATA TGTEILKNLV LPGIGSFTII 
        70         80         90        100        110        120 
DGNLVSGEDA GNNFFLQKSS IGKNRAQAAM EFLQELNSDV SGSFVEESPE NLLDNDPSFF 
       130        140        150        160        170        180 
CRFTIVVATQ LLESTLLRLA DVLWNSQIPL LICRTYGLVG YMRIIIKEHP VIESHPDNAL 
       190        200        210        220        230        240 
EDLRLDKPFP ELREHLQSYD LDHMEKKDHS HTPWIVIIAK YLAQWYNETN GRIPKSYKEK 
       250        260        270        280        290        300 
EDFRDLIRQG ILKNENGAPE DEENFEEAIK NVNTALNTTQ IPSSIEDIFN DDRCINITKQ 
       310        320        330        340        350        360 
TPTFWILARA LKEFVAKEGQ GNLPVRGTIP DMIADSNKYI KLQNVYREKA KKDAAAVGNH 
       370        380        390        400        410        420 
VAKLLQSVGQ APESISEKEL KLLCSNSAFL RVVRCRSLAE EYGLDTVNKD EIISSMDNPD 
       430        440        450        460        470        480 
NEIVLYLMLR AVDRFHKQHG RYPGVSNYQV EEDIGKLKSC LTGFLQEYGL SVMVKDDYVH 
       490        500        510        520        530    
EFCRYGAAEP HTIAAFLGGA AAQEVIKIIT KQFVIFNNTY IYSGMSQTSA TFQL

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)