Q8VBW6: NEDD8-activating enzyme E1 regulatory subunit
Protein names | - NEDD8-activating enzyme E1 regulatory subunit - Amyloid beta precursor protein-binding protein 1, 59 kDa - APP-BP1 - Amyloid protein-binding protein 1 |
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Gene names | Nae1 |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q8VBW6 |
4
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAQPGKILKE QKYDRQLRLW GDHGQEALES AHVCLINATA TGTEILKNLV LPGIGSFTII
70 80 90 100 110 120
DGNLVSGEDA GNNFFLQKSS IGKNRAQAAM EFLQELNSDV SGSFVEESPE NLLDNDPSFF
130 140 150 160 170 180
CRFTIVVATQ LLESTLLRLA DVLWNSQIPL LICRTYGLVG YMRIIIKEHP VIESHPDNAL
190 200 210 220 230 240
EDLRLDKPFP ELREHLQSYD LDHMEKKDHS HTPWIVIIAK YLAQWYNETN GRIPKSYKEK
250 260 270 280 290 300
EDFRDLIRQG ILKNENGAPE DEENFEEAIK NVNTALNTTQ IPSSIEDIFN DDRCINITKQ
310 320 330 340 350 360
TPTFWILARA LKEFVAKEGQ GNLPVRGTIP DMIADSNKYI KLQNVYREKA KKDAAAVGNH
370 380 390 400 410 420
VAKLLQSVGQ APESISEKEL KLLCSNSAFL RVVRCRSLAE EYGLDTVNKD EIISSMDNPD
430 440 450 460 470 480
NEIVLYLMLR AVDRFHKQHG RYPGVSNYQV EEDIGKLKSC LTGFLQEYGL SVMVKDDYVH
490 500 510 520 530
EFCRYGAAEP HTIAAFLGGA AAQEVIKIIT KQFVIFNNTY IYSGMSQTSA TFQL
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q8VBW6-2-unknown | MAQPGK... | 1 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | |||
Q8VBW6-2-unknown | MAQPGK... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q8VBW6-2-Acetylation | AQPGKI... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
Q8VBW6-2-Acetylation | AQPGKI... | 2 | acetylation- | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | ||
Q8VBW6-285-unknown | IEDIFN... | 285 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34115 | |||
Q8VBW6-340-unknown | IKLQNV... | 340 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30851 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...QIPSSI | 284 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34115 | |||
...DSNKYI | 339 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30851 | |||
...ATFQL | 534 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
MMP2_MOUSE | 284 | PSSI.|.IEDI | inferred from experiment | unknown | MEROPS | Overall CM | auf dem Keller U et al.:A statistics-based platform for... (M10.003) | 20305283, |
CATE_MOUSE | 339 | NKYI.|.IKLQ | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> ULA1_MOUSE @339 |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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