TopFIND 4.0

Q8WV28: B-cell linker protein

General Information

Protein names
- B-cell linker protein
- B-cell adapter containing a SH2 domain protein
- B-cell adapter containing a Src homology 2 domain protein
- Cytoplasmic adapter protein
- Src homology 2 domain-containing leukocyte protein of 65 kDa
- SLP-65
Gene names BLNK
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8WV28

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDKLNKITVP ASQKLRQLQK MVHDIKNNEG GIMNKIKKLK VKAPPSVPRR DYASESPADE 
        70         80         90        100        110        120 
EEQWSDDFDS DYENPDEHSD SEMYVMPAEE NADDSYEPPP VEQETRPVHP ALPFARGEYI 
       130        140        150        160        170        180 
DNRSSQRHSP PFSKTLPSKP SWPSEKARLT STLPALTALQ KPQVPPKPKG LLEDEADYVV 
       190        200        210        220        230        240 
PVEDNDENYI HPTESSSPPP EKAPMVNRST KPNSSTPASP PGTASGRNSG AWETKSPPPA 
       250        260        270        280        290        300 
APSPLPRAGK KPTTPLKTTP VASQQNASSV CEEKPIPAER HRGSSHRQEA VQSPVFPPAQ 
       310        320        330        340        350        360 
KQIHQKPIPL PRFTEGGNPT VDGPLPSFSS NSTISEQEAG VLCKPWYAGA CDRKSAEEAL 
       370        380        390        400        410        420 
HRSNKDGSFL IRKSSGHDSK QPYTLVVFFN KRVYNIPVRF IEATKQYALG RKKNGEEYFG 
       430        440        450    
SVAEIIRNHQ HSPLVLIDSQ NNTKDSTRLK YAVKVS

Isoforms

- Isoform 2 of B-cell linker protein - Isoform 3 of B-cell linker protein

Sequence View

        10         20         30         40         50         60 
MDKLNKITVP ASQKLRQLQK MVHDIKNNEG GIMNKIKKLK VKAPPSVPRR DYASESPADE 
        70         80         90        100        110        120 
EEQWSDDFDS DYENPDEHSD SEMYVMPAEE NADDSYEPPP VEQETRPVHP ALPFARGEYI 
       130        140        150        160        170        180 
DNRSSQRHSP PFSKTLPSKP SWPSEKARLT STLPALTALQ KPQVPPKPKG LLEDEADYVV 
       190        200        210        220        230        240 
PVEDNDENYI HPTESSSPPP EKAPMVNRST KPNSSTPASP PGTASGRNSG AWETKSPPPA 
       250        260        270        280        290        300 
APSPLPRAGK KPTTPLKTTP VASQQNASSV CEEKPIPAER HRGSSHRQEA VQSPVFPPAQ 
       310        320        330        340        350        360 
KQIHQKPIPL PRFTEGGNPT VDGPLPSFSS NSTISEQEAG VLCKPWYAGA CDRKSAEEAL 
       370        380        390        400        410        420 
HRSNKDGSFL IRKSSGHDSK QPYTLVVFFN KRVYNIPVRF IEATKQYALG RKKNGEEYFG 
       430        440        450    
SVAEIIRNHQ HSPLVLIDSQ NNTKDSTRLK YAVKVS         10         20         30         40         50         60 
MDKLNKITVP ASQKLRQLQK MVHDIKNNEG GIMNKIKKLK VKAPPSVPRR DYASESPADE 
        70         80         90        100        110        120 
EEQWSDDFDS DYENPDEHSD SEMYVMPAEE NADDSYEPPP VEQETRPVHP ALPFARGEYI 
       130        140        150        160        170        180 
DNRSSQRHSP PFSKTLPSKP SWPSEKARLT STLPALTALQ KPQVPPKPKG LLEDEADYVV 
       190        200        210        220        230        240 
PVEDNDENYI HPTESSSPPP EKAPMVNRST KPNSSTPASP PGTASGRNSG AWETKSPPPA 
       250        260        270        280        290        300 
APSPLPRAGK KPTTPLKTTP VASQQNASSV CEEKPIPAER HRGSSHRQEA VQSPVFPPAQ 
       310        320        330        340        350        360 
KQIHQKPIPL PRFTEGGNPT VDGPLPSFSS NSTISEQEAG VLCKPWYAGA CDRKSAEEAL 
       370        380        390        400        410        420 
HRSNKDGSFL IRKSSGHDSK QPYTLVVFFN KRVYNIPVRF IEATKQYALG RKKNGEEYFG 
       430        440        450    
SVAEIIRNHQ HSPLVLIDSQ NNTKDSTRLK YAVKVS



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Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)