Q91Z31: Polypyrimidine tract-binding protein 2

General Information

Protein names	- Polypyrimidine tract-binding protein 2 - Brain-enriched polypyrimidine tract-binding protein - Brain-enriched PTB - Neural polypyrimidine tract-binding protein - RRM-type RNA-binding protein brPTB
Gene names	Ptbp2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q91Z31

4 N-termini

3 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDGIVTEVAV GVKRGSDELL SGSVLSSPNS NMSGMVVTAN GNDSKKFKGE DKMDGAPSRV
        70         80         90        100        110        120
LHIRKLPGEV TETEVIALGL PFGKVTNILM LKGKNQAFLE LATEEAAITM VNYYSAVTPH
       130        140        150        160        170        180
LRNQPIYIQY SNHKELKTDN TLNQRAQVVL QAVTAVQTAN TPLSGTTVSE SAVTPAQSPV
       190        200        210        220        230        240
LRIIIDNMYY PVTLDVLHQI FSKFGAVLKI ITFTKNNQFQ ALLQYGDPVN AQQAKLALDG
       250        260        270        280        290        300
QNIYNACCTL RIDFSKLVNL NVKYNNDKSR DYTRPDLPSG DGQPALDPAI AAAFAKETSL
       310        320        330        340        350        360
LAVPGALSPL AIPNAAAAAA AAAAGRVGMP GVSAGGNTVL LVSNLNEEMV TPQSLFTLFG
       370        380        390        400        410        420
VYGDVQRVKI LYNKKDSALI QMADGNQSQL AMNHLNGQKM YGKIIRVTLS KHQTVQLPRE
       430        440        450        460        470        480
GLDDQGLTKD FGNSPLHRFK KPGSKNFQNI FPPSATLHLS NIPPSVAEED LRTLFANTGG
       490        500        510        520        530
TVKAFKFFQD HKMALLQMAT VEEAIQALID LHNYNLGENH HLRVSFSKST I

Isoforms

- Isoform 2 of Polypyrimidine tract-binding protein 2

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q91Z31-1-Acetylation	MDGIVT...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q91Z31-1-Acetylation	MDGIVT...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt98522
Q91Z31-1-unknown	MDGIVT...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86438
Q91Z31-359-unknown	FGVYGD...	359		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29280
Q91Z31-359-unknown	FGVYGD...	359		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30908
Q91Z31-359-unknown	FGVYGD...	359		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt151134
Q91Z31-360-unknown	GVYGDV...	360		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30910
Q91Z31-360-unknown	GVYGDV...	360		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt151180

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SLFTLF	358	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29280
...SLFTLF	358	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30908
...SLFTLF	358	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134536
...LFTLFG	359	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30910
...LFTLFG	359	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134582
...SKSTI	531	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SKSTI	531	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82056

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATD_MOUSE	358	FTLF.\|.FGVY	inferred from experiment	unknown	MEROPS	Zornig M	Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009)	22388353,
CATE_MOUSE	358	FTLF.\|.FGVY	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PTBP2_MOUSE @358
CATE_MOUSE	359	TLFG.\|.GVYG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PTBP2_MOUSE @359

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)