Q922R8: Protein disulfide-isomerase A6

General Information

Protein names	- Protein disulfide-isomerase A6 - 5.3.4.1 {ECO:0000250\|UniProtKB:Q15084} - Thioredoxin domain-containing protein 7
Gene names	Pdia6
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q922R8

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MARLVLGLVS CTFFLAVSGL YSSSDDVIEL TPSNFNREVI QSDGLWLVEF YAPWCGHCQR
        70         80         90        100        110        120
LTPEWKKAAT ALKDVVKVGA VNADKHQSLG GQYGVQGFPT IKIFGANKNK PEDYQGGRTG
       130        140        150        160        170        180
EAIVDAALSA LRQLVKDRLG GRSGGYSSGK QGRGDSSSKK DVVELTDDTF DKNVLDSEDV
       190        200        210        220        230        240
WMVEFYAPWC GHCKNLEPEW AAAATEVKEQ TKGKVKLAAV DATVNQVLAS RYGIKGFPTI
       250        260        270        280        290        300
KIFQKGESPV DYDGGRTRSD IVSRALDLFS DNAPPPELLE IINEDIAKKT CEEHQLCVVA
       310        320        330        340        350        360
VLPHILDTGA AGRNSYLEVL LKLADKYKKK MWGWLWTEAG AQYELENALG IGGFGYPAMA
       370        380        390        400        410        420
AINARKMKFA LLKGSFSEQG INEFLRELSF GRGSTAPVGG GSFPTITPRE PWDGKDGELP
       430        440
VEDDIDLSDV ELDDLEKDEL

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q922R8-20-unknown	LYSSSD...	20	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q922R8-20-unknown	LYSSSD...	20	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q922R8-20-unmodified	LYSSSD...	20		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
Q922R8-74-unknown	DVVKVG...	74	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q922R8-218-unknown	AAVDAT...	218	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30926

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...GKVKLA	217	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30926
	...EKDEL	440	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	217	VKLA.\|.AAVD	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PDIA6_MOUSE @217

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)