Q92890: Ubiquitin recognition factor in ER-associated degradation protein 1 {ECO:0000312|HGNC:HGNC:12520}

General Information

Protein names	- Ubiquitin recognition factor in ER-associated degradation protein 1 {ECO:0000312\|HGNC:HGNC:12520} - Ubiquitin fusion degradation protein 1 - UB fusion protein 1
Gene names	UFD1L
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q92890

6 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform Long of Ubiquitin fusion degradation protein 1 homolog - Isoform 3 of Ubiquitin fusion degradation protein 1 homolog - Isoform Long of Ubiquitin recognition factor in ER-associated degradation protein 1 - Isoform 3 of Ubiquitin recognition factor in ER-associated degradation protein 1

Sequence View

        10         20         30         40         50         60
MFSFNMFDHP IPRVFQNRFS TQYRCFSVSM LAGPNDRSDV EKGGKIIMPP SALDQLSRLN
        70         80         90        100        110        120
ITYPMLFKLT NKNSDRMTHC GVLEFVADEG ICYLPHWMMQ NLLLEEGGLV QVESVNLQVA
       130        140        150        160        170        180
TYSKFQPQSP DFLDITNPKA VLENALRNFA CLTTGDVIAI NYNEKIYELR VMETKPDKAV
       190        200        210        220        230        240
SIIECDMNVD FDAPLGYKEP ERQVQHEEST EGEADHSGYA GELGFRAFSG SGNRLDGKKK
       250        260        270        280        290        300
GVEPSPSPIK PGDIKRGIPN YEFKLGKITF IRNSRPLVKK VEEDEAGGRF VAFSGEGQSL

RKKGRKP         10         20         30         40         50         60
MFSFNMFDHP IPRVFQNRFS TQYRCFSVSM LAGPNDRSDV EKGGKIIMPP SALDQLSRLN
        70         80         90        100        110        120
ITYPMLFKLT NKNSDRMTHC GVLEFVADEG ICYLPHWMMQ NLLLEEGGLV QVESVNLQVA
       130        140        150        160        170        180
TYSKFQPQSP DFLDITNPKA VLENALRNFA CLTTGDVIAI NYNEKIYELR VMETKPDKAV
       190        200        210        220        230        240
SIIECDMNVD FDAPLGYKEP ERQVQHEEST EGEADHSGYA GELGFRAFSG SGNRLDGKKK
       250        260        270        280        290        300
GVEPSPSPIK PGDIKRGIPN YEFKLGKITF IRNSRPLVKK VEEDEAGGRF VAFSGEGQSL

RKKGRKP         10         20         30         40         50         60
MFSFNMFDHP IPRVFQNRFS TQYRCFSVSM LAGPNDRSDV EKGGKIIMPP SALDQLSRLN
        70         80         90        100        110        120
ITYPMLFKLT NKNSDRMTHC GVLEFVADEG ICYLPHWMMQ NLLLEEGGLV QVESVNLQVA
       130        140        150        160        170        180
TYSKFQPQSP DFLDITNPKA VLENALRNFA CLTTGDVIAI NYNEKIYELR VMETKPDKAV
       190        200        210        220        230        240
SIIECDMNVD FDAPLGYKEP ERQVQHEEST EGEADHSGYA GELGFRAFSG SGNRLDGKKK
       250        260        270        280        290        300
GVEPSPSPIK PGDIKRGIPN YEFKLGKITF IRNSRPLVKK VEEDEAGGRF VAFSGEGQSL

RKKGRKP         10         20         30         40         50         60
MFSFNMFDHP IPRVFQNRFS TQYRCFSVSM LAGPNDRSDV EKGGKIIMPP SALDQLSRLN
        70         80         90        100        110        120
ITYPMLFKLT NKNSDRMTHC GVLEFVADEG ICYLPHWMMQ NLLLEEGGLV QVESVNLQVA
       130        140        150        160        170        180
TYSKFQPQSP DFLDITNPKA VLENALRNFA CLTTGDVIAI NYNEKIYELR VMETKPDKAV
       190        200        210        220        230        240
SIIECDMNVD FDAPLGYKEP ERQVQHEEST EGEADHSGYA GELGFRAFSG SGNRLDGKKK
       250        260        270        280        290        300
GVEPSPSPIK PGDIKRGIPN YEFKLGKITF IRNSRPLVKK VEEDEAGGRF VAFSGEGQSL

RKKGRKP

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q92890-1-Acetylation	MFSFNM...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q92890-1-Acetylation	MFSFNM...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q92890-1-Acetylation	MFSFNM...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt98921
Q92890-1-unknown	MFSFNM...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93837
Q92890-6-	MFDHPI...	6			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q92890-6-unknown	MFDHPI...	6		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt168499
Q92890-203-	QVQHEE...	203			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q92890-203-unknown	QVQHEE...	203		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173918

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...EFKLGK	266	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt89455
	...KGRKP	307	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)