Q92947: Glutaryl-CoA dehydrogenase, mitochondrial

General Information

Protein names	- Glutaryl-CoA dehydrogenase, mitochondrial - GCD - 1.3.8.6
Gene names	GCDH
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q92947

6 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MALRGVSVRL LSRGPGLHVL RTWVSSAAQT EKGGRTQSQL AKSSRPEFDW QDPLVLEEQL
        70         80         90        100        110        120
TTDEILIRDT FRTYCQERLM PRILLANRNE VFHREIISEM GELGVLGPTI KGYGCAGVSS
       130        140        150        160        170        180
VAYGLLAREL ERVDSGYRSA MSVQSSLVMH PIYAYGSEEQ RQKYLPQLAK GELLGCFGLT
       190        200        210        220        230        240
EPNSGSDPSS METRAHYNSS NKSYTLNGTK TWITNSPMAD LFVVWARCED GCIRGFLLEK
       250        260        270        280        290        300
GMRGLSAPRI QGKFSLRASA TGMIIMDGVE VPEENVLPGA SSLGGPFGCL NNARYGIAWG
       310        320        330        340        350        360
VLGASEFCLH TARQYALDRM QFGVPLARNQ LIQKKLADML TEITLGLHAC LQLGRLKDQD
       370        380        390        400        410        420
KAAPEMVSLL KRNNCGKALD IARQARDMLG GNGISDEYHV IRHAMNLEAV NTYEGTHDIH
       430
ALILGRAITG IQAFTASK

Isoforms

- Isoform Short of Glutaryl-CoA dehydrogenase, mitochondrial

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q92947-1-unknown	MALRGV...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt75784
Q92947-24-	VSSAAQ...	24		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q92947-24-	VSSAAQ...	24		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q92947-24-	VSSAAQ...	24		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q92947-24-	VSSAAQ...	24		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
Q92947-24-	VSSAAQ...	24		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q92947-24-	VSSAAQ...	24		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q92947-24-	VSSAAQ...	24		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q92947-24-	VSSAAQ...	24		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q92947-24-	VSSAAQ...	24		Subtiligase Based Positive Selection		Wells	RMPI_untreated	23264352
Q92947-24-	VSSAAQ...	24		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q92947-24-unknown	VSSAAQ...	24		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q92947-24-unknown	VSSAAQ...	24		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q92947-24-unknown	VSSAAQ...	24	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt159661
Q92947-25-	SSAAQT...	25		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q92947-25-	SSAAQT...	25		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q92947-25-	SSAAQT...	25		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q92947-25-unknown	SSAAQT...	25		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q92947-25-unknown	SSAAQT...	25	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt159659
Q92947-45-unknown	RPEFDW...	45	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q92947-45-unknown	RPEFDW...	45	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt115541

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...FTASK	438	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...FTASK	438		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...FTASK	438		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...FTASK	438		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...FTASK	438		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)