Q96PZ0: Pseudouridylate synthase 7 homolog {ECO:0000305}

General Information

Protein names	- Pseudouridylate synthase 7 homolog {ECO:0000305} - 5.4.99.- {ECO:0000305\|PubMed:28073919}
Gene names	PUS7
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96PZ0

4 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEMTEMTGVS LKRGALVVED NDSGVPVEET KKQKLSECSL TKGQDGLQND FLSISEDVPR
        70         80         90        100        110        120
PPDTVSTGKG GKNSEAQLED EEEEEEDGLS EECEEEESES FADMMKHGLT EADVGITKFV
       130        140        150        160        170        180
SSHQGFSGIL KERYSDFVVH EIGKDGRISH LNDLSIPVDE EDPSEDIFTV LTAEEKQRLE
       190        200        210        220        230        240
ELQLFKNKET SVAIEVIEDT KEKRTIIHQA IKSLFPGLET KTEDREGKKY IVAYHAAGKK
       250        260        270        280        290        300
ALANPRKHSW PKSRGSYCHF VLYKENKDTM DAINVLSKYL RVKPNIFSYM GTKDKRAITV
       310        320        330        340        350        360
QEIAVLKITA QRLAHLNKCL MNFKLGNFSY QKNPLKLGEL QGNHFTVVLR NITGTDDQVQ
       370        380        390        400        410        420
QAMNSLKEIG FINYYGMQRF GTTAVPTYQV GRAILQNSWT EVMDLILKPR SGAEKGYLVK
       430        440        450        460        470        480
CREEWAKTKD PTAALRKLPV KRCVEGQLLR GLSKYGMKNI VSAFGIIPRN NRLMYIHSYQ
       490        500        510        520        530        540
SYVWNNMVSK RIEDYGLKPV PGDLVLKGAT ATYIEEDDVN NYSIHDVVMP LPGFDVIYPK
       550        560        570        580        590        600
HKIQEAYREM LTADNLDIDN MRHKIRDYSL SGAYRKIIIR PQNVSWEVVA YDDPKIPLFN
       610        620        630        640        650        660
TDVDNLEGKT PPVFASEGKY RALKMDFSLP PSTYATMAIR EVLKMDTSIK NQTQLNTTWL

R

Isoforms

- Isoform 2 of Pseudouridylate synthase 7 homolog

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q96PZ0-1-Acetylation	MEMTEM...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q96PZ0-1-Acetylation	MEMTEM...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q96PZ0-1-Acetylation	MEMTEM...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q96PZ0-23-	SGVPVE...	23			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q96PZ0-51-	FLSISE...	51			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q96PZ0-51-	FLSISE...	51			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q96PZ0-497-unknown	LKPVPG...	497		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6692

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FSYMGT	291	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000417718
...IEDYGL	496	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6692
...TTWLR	661	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	496	DYGL.\|.LKPV	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)