Q96Q83: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 {ECO:0000305}

General Information

Protein names	- Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 {ECO:0000305} - 1.14.11.54 {ECO:0000269\|PubMed:16858410, ECO:0000269\|PubMed:22055184, ECO:0000305\|PubMed:26863196} - Alkylated DNA repair protein alkB homolog 3 {ECO:0000303\|PubMed:12594517} - hABH3 {ECO:0000303\|PubMed:12594517} - DEPC-1 {ECO:0000303\|Ref.1} - Prostate cancer antigen 1 {ECO:0000303\|Ref.1}
Gene names	ALKBH3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96Q83

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEEKRRRARV QGAWAAPVKS QAIAQPATTA KSHLHQKPGQ TWKNKEHHLS DREFVFKEPQ
        70         80         90        100        110        120
QVVRRAPEPR VIDREGVYEI SLSPTGVSRV CLYPGFVDVK EADWILEQLC QDVPWKQRTG
       130        140        150        160        170        180
IREDITYQQP RLTAWYGELP YTYSRITMEP NPHWHPVLRT LKNRIEENTG HTFNSLLCNL
       190        200        210        220        230        240
YRNEKDSVDW HSDDEPSLGR CPIIASLSFG ATRTFEMRKK PPPEENGDYT YVERVKIPLD
       250        260        270        280
HGTLLIMEGA TQADWQHRVP KEYHSREPRV NLTFRTVYPD PRGAPW

Isoforms

- Isoform 2 of Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q96Q83-1-unknown	MEEKRR...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q96Q83-1-unknown	MEEKRR...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt66744
Q96Q83-15-unknown	AAPVKS...	15	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt167665
Q96Q83-15-	AAPVKS...	15		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q96Q83-15-	AAPVKS...	15		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q96Q83-55-unknown	VFKEPQ...	55		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...RGAPW	286	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)