Q96RF0: Sorting nexin-18

General Information

Protein names	- Sorting nexin-18 - SH3 and PX domain-containing protein 3B - Sorting nexin-associated Golgi protein 1
Gene names	SNX18
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96RF0

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Sorting nexin-18 - Isoform 3 of Sorting nexin-18

Sequence View

        10         20         30         40         50         60
MALRARALYD FRSENPGEIS LREHEVLSLC SEQDIEGWLE GVNSRGDRGL FPASYVQVIR
        70         80         90        100        110        120
APEPGPAGDG GPGAPARYAN VPPGGFEPLP VAPPASFKPP PDAFQALLQP QQAPPPSTFQ
       130        140        150        160        170        180
PPGAGFPYGG GALQPSPQQL YGGYQASQGS DDDWDDEWDD SSTVADEPGA LGSGAYPDLD
       190        200        210        220        230        240
GSSSAGVGAA GRYRLSTRSD LSLGSRGGSV PPQHHPSGPK SSATVSRNLN RFSTFVKSGG
       250        260        270        280        290        300
EAFVLGEASG FVKDGDKLCV VLGPYGPEWQ ENPYPFQCTI DDPTKQTKFK GMKSYISYKL
       310        320        330        340        350        360
VPTHTQVPVH RRYKHFDWLY ARLAEKFPVI SVPHLPEKQA TGRFEEDFIS KRRKGLIWWM
       370        380        390        400        410        420
NHMASHPVLA QCDVFQHFLT CPSSTDEKAW KQGKRKAEKD EMVGANFFLT LSTPPAAALD
       430        440        450        460        470        480
LQEVESKIDG FKCFTKKMDD SALQLNHTAN EFARKQVTGF KKEYQKVGQS FRGLSQAFEL
       490        500        510        520        530        540
DQQAFSVGLN QAIAFTGDAY DAIGELFAEQ PRQDLDPVMD LLALYQGHLA NFPDIIHVQK
       550        560        570        580        590        600
GKAWPLEQVI WSVLCRLKGA TLTAVPLWVS ESYSTGEEAS RDVDAWVFSL ECKLDCSTGS
       610        620
FLLEYLALGN EYSFSKVQRV PLMTVLSF         10         20         30         40         50         60
MALRARALYD FRSENPGEIS LREHEVLSLC SEQDIEGWLE GVNSRGDRGL FPASYVQVIR
        70         80         90        100        110        120
APEPGPAGDG GPGAPARYAN VPPGGFEPLP VAPPASFKPP PDAFQALLQP QQAPPPSTFQ
       130        140        150        160        170        180
PPGAGFPYGG GALQPSPQQL YGGYQASQGS DDDWDDEWDD SSTVADEPGA LGSGAYPDLD
       190        200        210        220        230        240
GSSSAGVGAA GRYRLSTRSD LSLGSRGGSV PPQHHPSGPK SSATVSRNLN RFSTFVKSGG
       250        260        270        280        290        300
EAFVLGEASG FVKDGDKLCV VLGPYGPEWQ ENPYPFQCTI DDPTKQTKFK GMKSYISYKL
       310        320        330        340        350        360
VPTHTQVPVH RRYKHFDWLY ARLAEKFPVI SVPHLPEKQA TGRFEEDFIS KRRKGLIWWM
       370        380        390        400        410        420
NHMASHPVLA QCDVFQHFLT CPSSTDEKAW KQGKRKAEKD EMVGANFFLT LSTPPAAALD
       430        440        450        460        470        480
LQEVESKIDG FKCFTKKMDD SALQLNHTAN EFARKQVTGF KKEYQKVGQS FRGLSQAFEL
       490        500        510        520        530        540
DQQAFSVGLN QAIAFTGDAY DAIGELFAEQ PRQDLDPVMD LLALYQGHLA NFPDIIHVQK
       550        560        570        580        590        600
GKAWPLEQVI WSVLCRLKGA TLTAVPLWVS ESYSTGEEAS RDVDAWVFSL ECKLDCSTGS
       610        620
FLLEYLALGN EYSFSKVQRV PLMTVLSF

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q96RF0-1-unknown	MALRAR...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q96RF0-1-unknown	MALRAR...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90173
Q96RF0-1-unknown	MALRAR...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90174
Q96RF0-181-unknown	GSSSAG...	181	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173973
Q96RF0-181-unknown	GSSSAG...	181	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173974
Q96RF0-181-	GSSSAG...	181		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q96RF0-181-	GSSSAG...	181		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...VFSLEC	591	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt85792
	...TVLSF	628	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)