Q96RU3: Formin-binding protein 1

General Information

Protein names	- Formin-binding protein 1 - Formin-binding protein 17 - hFBP17
Gene names	FNBP1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96RU3

5 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Formin-binding protein 1 - Isoform 3 of Formin-binding protein 1 - Isoform 4 of Formin-binding protein 1 - Isoform 5 of Formin-binding protein 1

Sequence View

        10         20         30         40         50         60
MSWGTELWDQ FDNLEKHTQW GIDILEKYIK FVKERTEIEL SYAKQLRNLS KKYQPKKNSK
        70         80         90        100        110        120
EEEEYKYTSC KAFISNLNEM NDYAGQHEVI SENMASQIIV DLARYVQELK QERKSNFHDG
       130        140        150        160        170        180
RKAQQHIETC WKQLESSKRR FERDCKEADR AQQYFEKMDA DINVTKADVE KARQQAQIRH
       190        200        210        220        230        240
QMAEDSKADY SSILQKFNHE QHEYYHTHIP NIFQKIQEME ERRIVRMGES MKTYAEVDRQ
       250        260        270        280        290        300
VIPIIGKCLD GIVKAAESID QKNDSQLVIE AYKSGFEPPG DIEFEDYTQP MKRTVSDNSL
       310        320        330        340        350        360
SNSRGEGKPD LKFGGKSKGK LWPFIKKNKL MSLLTSPHQP PPPPPASASP SAVPNGPQSP
       370        380        390        400        410        420
KQQKEPLSHR FNEFMTSKPK IHCFRSLKRG LSLKLGATPE DFSNLPPEQR RKKLQQKVDE
       430        440        450        460        470        480
LNKEIQKEMD QRDAITKMKD VYLKNPQMGD PASLDHKLAE VSQNIEKLRV ETQKFEAWLA
       490        500        510        520        530        540
EVEGRLPARS EQARRQSGLY DSQNPPTVNN CAQDRESPDG SYTEEQSQES EMKVLATDFD
       550        560        570        580        590        600
DEFDDEEPLP AIGTCKALYT FEGQNEGTIS VVEGETLYVI EEDKGDGWTR IRRNEDEEGY
       610
VPTSYVEVCL DKNAKDS         10         20         30         40         50         60
MSWGTELWDQ FDNLEKHTQW GIDILEKYIK FVKERTEIEL SYAKQLRNLS KKYQPKKNSK
        70         80         90        100        110        120
EEEEYKYTSC KAFISNLNEM NDYAGQHEVI SENMASQIIV DLARYVQELK QERKSNFHDG
       130        140        150        160        170        180
RKAQQHIETC WKQLESSKRR FERDCKEADR AQQYFEKMDA DINVTKADVE KARQQAQIRH
       190        200        210        220        230        240
QMAEDSKADY SSILQKFNHE QHEYYHTHIP NIFQKIQEME ERRIVRMGES MKTYAEVDRQ
       250        260        270        280        290        300
VIPIIGKCLD GIVKAAESID QKNDSQLVIE AYKSGFEPPG DIEFEDYTQP MKRTVSDNSL
       310        320        330        340        350        360
SNSRGEGKPD LKFGGKSKGK LWPFIKKNKL MSLLTSPHQP PPPPPASASP SAVPNGPQSP
       370        380        390        400        410        420
KQQKEPLSHR FNEFMTSKPK IHCFRSLKRG LSLKLGATPE DFSNLPPEQR RKKLQQKVDE
       430        440        450        460        470        480
LNKEIQKEMD QRDAITKMKD VYLKNPQMGD PASLDHKLAE VSQNIEKLRV ETQKFEAWLA
       490        500        510        520        530        540
EVEGRLPARS EQARRQSGLY DSQNPPTVNN CAQDRESPDG SYTEEQSQES EMKVLATDFD
       550        560        570        580        590        600
DEFDDEEPLP AIGTCKALYT FEGQNEGTIS VVEGETLYVI EEDKGDGWTR IRRNEDEEGY
       610
VPTSYVEVCL DKNAKDS         10         20         30         40         50         60
MSWGTELWDQ FDNLEKHTQW GIDILEKYIK FVKERTEIEL SYAKQLRNLS KKYQPKKNSK
        70         80         90        100        110        120
EEEEYKYTSC KAFISNLNEM NDYAGQHEVI SENMASQIIV DLARYVQELK QERKSNFHDG
       130        140        150        160        170        180
RKAQQHIETC WKQLESSKRR FERDCKEADR AQQYFEKMDA DINVTKADVE KARQQAQIRH
       190        200        210        220        230        240
QMAEDSKADY SSILQKFNHE QHEYYHTHIP NIFQKIQEME ERRIVRMGES MKTYAEVDRQ
       250        260        270        280        290        300
VIPIIGKCLD GIVKAAESID QKNDSQLVIE AYKSGFEPPG DIEFEDYTQP MKRTVSDNSL
       310        320        330        340        350        360
SNSRGEGKPD LKFGGKSKGK LWPFIKKNKL MSLLTSPHQP PPPPPASASP SAVPNGPQSP
       370        380        390        400        410        420
KQQKEPLSHR FNEFMTSKPK IHCFRSLKRG LSLKLGATPE DFSNLPPEQR RKKLQQKVDE
       430        440        450        460        470        480
LNKEIQKEMD QRDAITKMKD VYLKNPQMGD PASLDHKLAE VSQNIEKLRV ETQKFEAWLA
       490        500        510        520        530        540
EVEGRLPARS EQARRQSGLY DSQNPPTVNN CAQDRESPDG SYTEEQSQES EMKVLATDFD
       550        560        570        580        590        600
DEFDDEEPLP AIGTCKALYT FEGQNEGTIS VVEGETLYVI EEDKGDGWTR IRRNEDEEGY
       610
VPTSYVEVCL DKNAKDS         10         20         30         40         50         60
MSWGTELWDQ FDNLEKHTQW GIDILEKYIK FVKERTEIEL SYAKQLRNLS KKYQPKKNSK
        70         80         90        100        110        120
EEEEYKYTSC KAFISNLNEM NDYAGQHEVI SENMASQIIV DLARYVQELK QERKSNFHDG
       130        140        150        160        170        180
RKAQQHIETC WKQLESSKRR FERDCKEADR AQQYFEKMDA DINVTKADVE KARQQAQIRH
       190        200        210        220        230        240
QMAEDSKADY SSILQKFNHE QHEYYHTHIP NIFQKIQEME ERRIVRMGES MKTYAEVDRQ
       250        260        270        280        290        300
VIPIIGKCLD GIVKAAESID QKNDSQLVIE AYKSGFEPPG DIEFEDYTQP MKRTVSDNSL
       310        320        330        340        350        360
SNSRGEGKPD LKFGGKSKGK LWPFIKKNKL MSLLTSPHQP PPPPPASASP SAVPNGPQSP
       370        380        390        400        410        420
KQQKEPLSHR FNEFMTSKPK IHCFRSLKRG LSLKLGATPE DFSNLPPEQR RKKLQQKVDE
       430        440        450        460        470        480
LNKEIQKEMD QRDAITKMKD VYLKNPQMGD PASLDHKLAE VSQNIEKLRV ETQKFEAWLA
       490        500        510        520        530        540
EVEGRLPARS EQARRQSGLY DSQNPPTVNN CAQDRESPDG SYTEEQSQES EMKVLATDFD
       550        560        570        580        590        600
DEFDDEEPLP AIGTCKALYT FEGQNEGTIS VVEGETLYVI EEDKGDGWTR IRRNEDEEGY
       610
VPTSYVEVCL DKNAKDS

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q96RU3-1-unknown	MSWGTE...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q96RU3-1-unknown	MSWGTE...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt75323
Q96RU3-1-unknown	MSWGTE...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt75324
Q96RU3-1-unknown	MSWGTE...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt75325
Q96RU3-2-	SWGTEL...	2		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q96RU3-2-unknown	SWGTEL...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170906
Q96RU3-2-unknown	SWGTEL...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170907
Q96RU3-2-unknown	SWGTEL...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170908
Q96RU3-520-	GSYTEE...	520		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q96RU3-520-	GSYTEE...	520		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
Q96RU3-520-	GSYTEE...	520		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q96RU3-520-	GSYTEE...	520		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q96RU3-520-	GSYTEE...	520		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q96RU3-520-unknown	GSYTEE...	520		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q96RU3-520-unknown	GSYTEE...	520	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161564
Q96RU3-520-unknown	GSYTEE...	520	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161565
Q96RU3-520-unknown	GSYTEE...	520	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161566

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...NAKDS	617	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...NAKDS	617	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt70943

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)