Q96RY7: Intraflagellar transport protein 140 homolog {ECO:0000305}

General Information

Protein names	- Intraflagellar transport protein 140 homolog {ECO:0000305} - WD and tetratricopeptide repeats protein 2
Gene names	IFT140
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96RY7

4 N-termini

4 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MALYYDHQIE APDAAGSPSF ISWHPVHPFL AVAYISTTST GSVDIYLEQG ECVPDTHVER
        70         80         90        100        110        120
PFRVASLCWH PTRLVLAVGW ETGEVTVFNK QDKEQHTMPL THTADITVLR WSPSGNCLLS
       130        140        150        160        170        180
GDRLGVLLLW RLDQRGRVQG TPLLKHEYGK HLTHCIFRLP PPGEDLVQLA KAAVSGDEKA
       190        200        210        220        230        240
LDMFNWKKSS SGSLLKMGSH EGLLFFVSLM DGTVHYVDEK GKTTQVVSAD STIQMLFYME
       250        260        270        280        290        300
KREALVVVTE NLRLSLYTVP PEGKAEEVMK VKLSGKTGRR ADIALIEGSL LVMAVGEAAL
       310        320        330        340        350        360
RFWDIERGEN YILSPDEKFG FEKGENMNCV CYCKVKGLLA AGTDRGRVAM WRKVPDFLGS
       370        380        390        400        410        420
PGAEGKDRWA LQTPTELQGN ITQIQWGSRK NLLAVNSVIS VAILSERAMS SHFHQQVAAM
       430        440        450        460        470        480
QVSPSLLNVC FLSTGVAHSL RTDMHISGVF ATKDAVAVWN GRQVAIFELS GAAIRSAGTF
       490        500        510        520        530        540
LCETPVLAMH EENVYTVESN RVQVRTWQGT VKQLLLFSET EGNPCFLDIC GNFLVVGTDL
       550        560        570        580        590        600
AHFKSFDLSR REAKAHCSCR SLAELVPGVG GIASLRCSSS GSTISILPSK ADNSPDSKIC
       610        620        630        640        650        660
FYDVEMDTVT VFDFKTGQID RRETLSFNEQ ETNKSHLFVD EGLKNYVPVN HFWDQSEPRL
       670        680        690        700        710        720
FVCEAVQETP RSQPQSANGQ PQDGRAGPAA DVLILSFFIS EEHGFLLHES FPRPATSHSL
       730        740        750        760        770        780
LGMEVPYYYF TRKPEEADRE DEVEPGCHHI PQMVSRRPLR DFVGLEDCDK ATRDAMLHFS
       790        800        810        820        830        840
FFVTIGDMDE AFKSIKLIKS EAVWENMARM CVKTQRLDVA KVCLGNMGHA RGARALREAE
       850        860        870        880        890        900
QEPELEARVA VLATQLGMLE DAEQLYRKCK RHDLLNKFYQ AAGRWQEALQ VAEHHDRVHL
       910        920        930        940        950        960
RSTYHRYAGH LEASADCSRA LSYYEKSDTH RFEVPRMLSE DLPSLELYVN KMKDKTLWRW
       970        980        990       1000       1010       1020
WAQYLESQGE MDAALHYYEL ARDHFSLVRI HCFQGNVQKA AQIANETGNL AASYHLARQY
      1030       1040       1050       1060       1070       1080
ESQEEVGQAV HFYTRAQAFK NAIRLCKENG LDDQLMNLAL LSSPEDMIEA ARYYEEKGVQ
      1090       1100       1110       1120       1130       1140
MDRAVMLYHK AGHFSKALEL AFATQQFVAL QLIAEDLDET SDPALLARCS DFFIEHSQYE
      1150       1160       1170       1180       1190       1200
RAVELLLAAR KYQEALQLCL GQNMSITEEM AEKMTVAKDS SDLPEESRRE LLEQIADCCM
      1210       1220       1230       1240       1250       1260
RQGSYHLATK KYTQAGNKLK AMRALLKSGD TEKITFFASV SRQKEIYIMA ANYLQSLDWR
      1270       1280       1290       1300       1310       1320
KEPEIMKNII GFYTKGRALD LLAGFYDACA QVEIDEYQNY DKAHGALTEA YKCLAKAKAK
      1330       1340       1350       1360       1370       1380
SPLDQETRLA QLQSRMALVK RFIQARRTYT EDPKESIKQC ELLLEEPDLD STIRIGDVYG
      1390       1400       1410       1420       1430       1440
FLVEHYVRKE EYQTAYRFLE EMRRRLPLAN MSYYVSPQAV DAVHRGLGLP LPRTVPEQVR
      1450       1460
HNSMEDAREL DEEVVEEADD DP

Isoforms

- Isoform 2 of Intraflagellar transport protein 140 homolog

Sequence View

        10         20         30         40         50         60
MALYYDHQIE APDAAGSPSF ISWHPVHPFL AVAYISTTST GSVDIYLEQG ECVPDTHVER
        70         80         90        100        110        120
PFRVASLCWH PTRLVLAVGW ETGEVTVFNK QDKEQHTMPL THTADITVLR WSPSGNCLLS
       130        140        150        160        170        180
GDRLGVLLLW RLDQRGRVQG TPLLKHEYGK HLTHCIFRLP PPGEDLVQLA KAAVSGDEKA
       190        200        210        220        230        240
LDMFNWKKSS SGSLLKMGSH EGLLFFVSLM DGTVHYVDEK GKTTQVVSAD STIQMLFYME
       250        260        270        280        290        300
KREALVVVTE NLRLSLYTVP PEGKAEEVMK VKLSGKTGRR ADIALIEGSL LVMAVGEAAL
       310        320        330        340        350        360
RFWDIERGEN YILSPDEKFG FEKGENMNCV CYCKVKGLLA AGTDRGRVAM WRKVPDFLGS
       370        380        390        400        410        420
PGAEGKDRWA LQTPTELQGN ITQIQWGSRK NLLAVNSVIS VAILSERAMS SHFHQQVAAM
       430        440        450        460        470        480
QVSPSLLNVC FLSTGVAHSL RTDMHISGVF ATKDAVAVWN GRQVAIFELS GAAIRSAGTF
       490        500        510        520        530        540
LCETPVLAMH EENVYTVESN RVQVRTWQGT VKQLLLFSET EGNPCFLDIC GNFLVVGTDL
       550        560        570        580        590        600
AHFKSFDLSR REAKAHCSCR SLAELVPGVG GIASLRCSSS GSTISILPSK ADNSPDSKIC
       610        620        630        640        650        660
FYDVEMDTVT VFDFKTGQID RRETLSFNEQ ETNKSHLFVD EGLKNYVPVN HFWDQSEPRL
       670        680        690        700        710        720
FVCEAVQETP RSQPQSANGQ PQDGRAGPAA DVLILSFFIS EEHGFLLHES FPRPATSHSL
       730        740        750        760        770        780
LGMEVPYYYF TRKPEEADRE DEVEPGCHHI PQMVSRRPLR DFVGLEDCDK ATRDAMLHFS
       790        800        810        820        830        840
FFVTIGDMDE AFKSIKLIKS EAVWENMARM CVKTQRLDVA KVCLGNMGHA RGARALREAE
       850        860        870        880        890        900
QEPELEARVA VLATQLGMLE DAEQLYRKCK RHDLLNKFYQ AAGRWQEALQ VAEHHDRVHL
       910        920        930        940        950        960
RSTYHRYAGH LEASADCSRA LSYYEKSDTH RFEVPRMLSE DLPSLELYVN KMKDKTLWRW
       970        980        990       1000       1010       1020
WAQYLESQGE MDAALHYYEL ARDHFSLVRI HCFQGNVQKA AQIANETGNL AASYHLARQY
      1030       1040       1050       1060       1070       1080
ESQEEVGQAV HFYTRAQAFK NAIRLCKENG LDDQLMNLAL LSSPEDMIEA ARYYEEKGVQ
      1090       1100       1110       1120       1130       1140
MDRAVMLYHK AGHFSKALEL AFATQQFVAL QLIAEDLDET SDPALLARCS DFFIEHSQYE
      1150       1160       1170       1180       1190       1200
RAVELLLAAR KYQEALQLCL GQNMSITEEM AEKMTVAKDS SDLPEESRRE LLEQIADCCM
      1210       1220       1230       1240       1250       1260
RQGSYHLATK KYTQAGNKLK AMRALLKSGD TEKITFFASV SRQKEIYIMA ANYLQSLDWR
      1270       1280       1290       1300       1310       1320
KEPEIMKNII GFYTKGRALD LLAGFYDACA QVEIDEYQNY DKAHGALTEA YKCLAKAKAK
      1330       1340       1350       1360       1370       1380
SPLDQETRLA QLQSRMALVK RFIQARRTYT EDPKESIKQC ELLLEEPDLD STIRIGDVYG
      1390       1400       1410       1420       1430       1440
FLVEHYVRKE EYQTAYRFLE EMRRRLPLAN MSYYVSPQAV DAVHRGLGLP LPRTVPEQVR
      1450       1460
HNSMEDAREL DEEVVEEADD DP

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q96RY7-1-unknown	MALYYD...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q96RY7-612-unknown	FDFKTG...	612	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19743
Q96RY7-807-unknown	MARMCV...	807	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000354895
Q96RY7-1295-unknown	DEYQNY...	1295	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000458439

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LRWSPS	113	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457092
...NCLLSG	120	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454781
...DTVTVF	611	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19743
...ADDDP	1462	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

TopFIND

Q96RY7: Intraflagellar transport protein 140 homolog {ECO:0000305}

General Information

4

N-termini

4

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates