Q96S52: GPI transamidase component PIG-S

General Information

Protein names	- GPI transamidase component PIG-S - Phosphatidylinositol-glycan biosynthesis class S protein
Gene names	PIGS
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96S52

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAAGAAATH LEVARGKRAA LFFAAVAIVL GLPLWWKTTE TYRASLPYSQ ISGLNALQLR
        70         80         90        100        110        120
LMVPVTVVFT RESVPLDDQE KLPFTVVHER EIPLKYKMKI KCRFQKAYRR ALDHEEEALS
       130        140        150        160        170        180
SGSVQEAEAM LDEPQEQAEG SLTVYVISEH SSLLPQDMMS YIGPKRTAVV RGIMHREAFN
       190        200        210        220        230        240
IIGRRIVQVA QAMSLTEDVL AAALADHLPE DKWSAEKRRP LKSSLGYEIT FSLLNPDPKS
       250        260        270        280        290        300
HDVYWDIEGA VRRYVQPFLN ALGAAGNFSV DSQILYYAML GVNPRFDSAS SSYYLDMHSL
       310        320        330        340        350        360
PHVINPVESR LGSSAASLYP VLNFLLYVPE LAHSPLYIQD KDGAPVATNA FHSPRWGGIM
       370        380        390        400        410        420
VYNVDSKTYN ASVLPVRVEV DMVRVMEVFL AQLRLLFGIA QPQLPPKCLL SGPTSEGLMT
       430        440        450        460        470        480
WELDRLLWAR SVENLATATT TLTSLAQLLG KISNIVIKDD VASEVYKAVA AVQKSAEELA
       490        500        510        520        530        540
SGHLASAFVA SQEAVTSSEL AFFDPSLLHL LYFPDDQKFA IYIPLFLPMA VPILLSLVKI
       550
FLETRKSWRK PEKTD

Isoforms

- Isoform 2 of GPI transamidase component PIG-S

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q96S52-2-	AAAGAA...	2		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q96S52-2-	AAAGAA...	2		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q96S52-2-	AAAGAA...	2		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
Q96S52-2-	AAAGAA...	2		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q96S52-2-unknown	AAAGAA...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...PEKTD	555	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...PEKTD	555	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt80834

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)