TopFIND 4.0

Q99972: Myocilin {ECO:0000303|PubMed:9169133}

General Information

Protein names
- Myocilin {ECO:0000303|PubMed:9169133}
- Myocilin 55 kDa subunit
- Trabecular meshwork-induced glucocorticoid response protein {ECO:0000303|PubMed:9497363}
- Myocilin, N-terminal fragment
- Myocilin 20 kDa N-terminal fragment
- Myocilin, C-terminal fragment
- Myocilin 35 kDa N-terminal fragment
Gene names MYOC
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q99972

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRFFCARCCS FGPEMPAVQL LLLACLVWDV GARTAQLRKA NDQSGRCQYT FSVASPNESS 
        70         80         90        100        110        120 
CPEQSQAMSV IHNLQRDSST QRLDLEATKA RLSSLESLLH QLTLDQAARP QETQEGLQRE 
       130        140        150        160        170        180 
LGTLRRERDQ LETQTRELET AYSNLLRDKS VLEEEKKRLR QENENLARRL ESSSQEVARL 
       190        200        210        220        230        240 
RRGQCPQTRD TARAVPPGSR EVSTWNLDTL AFQELKSELT EVPASRILKE SPSGYLRSGE 
       250        260        270        280        290        300 
GDTGCGELVW VGEPLTLRTA ETITGKYGVW MRDPKPTYPY TQETTWRIDT VGTDVRQVFE 
       310        320        330        340        350        360 
YDLISQFMQG YPSKVHILPR PLESTGAVVY SGSLYFQGAE SRTVIRYELN TETVKAEKEI 
       370        380        390        400        410        420 
PGAGYHGQFP YSWGGYTDID LAVDEAGLWV IYSTDEAKGA IVLSKLNPEN LELEQTWETN 
       430        440        450        460        470        480 
IRKQSVANAF IICGTLYTVS SYTSADATVN FAYDTGTGIS KTLTIPFKNR YKYSSMIDYN 
       490        500    
PLEKKLFAWD NLNMVTYDIK LSKM

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)