Q9BV57: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase {ECO:0000255|HAMAP-Rule:MF_03154}

General Information

Protein names	- 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase {ECO:0000255\|HAMAP-Rule:MF_03154} - 1.13.11.54 {ECO:0000255\|HAMAP-Rule:MF_03154} - Acireductone dioxygenase (Fe(2+)-requiring) {ECO:0000255\|HAMAP-Rule:MF_03154} - ARD {ECO:0000255\|HAMAP-Rule:MF_03154} - Fe-ARD {ECO:0000255\|HAMAP-Rule:MF_03154} - Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 {ECO:0000255\|HAMAP-Rule:MF_03154} - MTCBP-1 {ECO:0000255\|HAMAP-Rule:MF_03154} - Submergence-induced protein-like factor - Sip-L
Gene names	ADI1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9BV57

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVQAWYMDDA PGDPRQPHRP DPGRPVGLEQ LRRLGVLYWK LDADKYENDP ELEKIRRERN
        70         80         90        100        110        120
YSWMDIITIC KDKLPNYEEK IKMFYEEHLH LDDEIRYILD GSGYFDVRDK EDQWIRIFME
       130        140        150        160        170
KGDMVTLPAG IYHRFTVDEK NYTKAMRLFV GEPVWTAYNR PADHFEARGQ YVKFLAQTA

Isoforms

- Isoform 2 of 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase

Sequence View

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Physiological Relevance:

Evidence Codes:

Methodology:

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Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9BV57-1-unknown	MVQAWY...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9BV57-2-	VQAWYM...	2		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9BV57-2-	VQAWYM...	2		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9BV57-2-	VQAWYM...	2		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
Q9BV57-2-unknown	VQAWYM...	2		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...LAQTA	179		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...LAQTA	179		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...LAQTA	179	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...LAQTA	179	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt77392
...LAQTA	179		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...LAQTA	179		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)