Q9BXR0: Queuine tRNA-ribosyltransferase catalytic subunit 1 {ECO:0000255|HAMAP-Rule:MF_03218}

General Information

Protein names	- Queuine tRNA-ribosyltransferase catalytic subunit 1 {ECO:0000255\|HAMAP-Rule:MF_03218} - 2.4.2.29 {ECO:0000255\|HAMAP-Rule:MF_03218, ECO:0000269\|PubMed:20354154} - Guanine insertion enzyme {ECO:0000255\|HAMAP-Rule:MF_03218} - tRNA-guanine transglycosylase {ECO:0000255\|HAMAP-Rule:MF_03218}
Gene names	QTRT1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9BXR0

4 N-termini

4 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAGAATQASL ESAPRIMRLV AECSRSRARA GELWLPHGTV ATPVFMPVGT QATMKGITTE
        70         80         90        100        110        120
QLDALGCRIC LGNTYHLGLR PGPELIQKAN GLHGFMNWPH NLLTDSGGFQ MVSLVSLSEV
       130        140        150        160        170        180
TEEGVRFRSP YDGNETLLSP EKSVQIQNAL GSDIIMQLDD VVSSTVTGPR VEEAMYRSIR
       190        200        210        220        230        240
WLDRCIAAHQ RPDKQNLFAI IQGGLDADLR ATCLEEMTKR DVPGFAIGGL SGGESKSQFW
       250        260        270        280        290        300
RMVALSTSRL PKDKPRYLMG VGYATDLVVC VALGCDMFDC VFPTRTARFG SALVPTGNLQ
       310        320        330        340        350        360
LRKKVFEKDF GPIDPECTCP TCQKHSRAFL HALLHSDNTA ALHHLTVHNI AYQLQLMSAV
       370        380        390        400
RTSIVEKRFP DFVRDFMGAM YGDPTLCPTW ATDALASVGI TLG

Isoforms

- Isoform 2 of Queuine tRNA-ribosyltransferase catalytic subunit 1

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q9BXR0-2-unknown	MAGAAT...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9BXR0-2-Acetylation	AGAATQ...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9BXR0-79-unknown	LRPGPE...	79		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6752
Q9BXR0-266-unknown	DLVVCV...	266		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000465974

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TYHLGL	78	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6752
...KQNLFA	198	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000468811
...VALSTS	247	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000467394
...GITLG	403	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	78	HLGL.\|.LRPG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)