Q9BXS6: Nucleolar and spindle-associated protein 1

General Information

Protein names	- Nucleolar and spindle-associated protein 1 - NuSAP
Gene names	NUSAP1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9BXS6

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Nucleolar and spindle-associated protein 1 - Isoform 3 of Nucleolar and spindle-associated protein 1 - Isoform 4 of Nucleolar and spindle-associated protein 1 - Isoform 5 of Nucleolar and spindle-associated protein 1 - Isoform 6 of Nucleolar and spindle-associated protein 1 - Isoform 7 of Nucleolar and spindle-associated protein 1

Sequence View

        10         20         30         40         50         60
MIIPSLEELD SLKYSDLQNL AKSLGLRANL RATKLLKALK GYIKHEARKG NENQDESQTS
        70         80         90        100        110        120
ASSCDETEIQ ISNQEEAERQ PLGHVTKTRR RCKTVRVDPD SQQNHSEIKI SNPTEFQNHE
       130        140        150        160        170        180
KQESQDLRAT AKVPSPPDEH QEAENAVSSG NRDSKVPSEG KKSLYTDESS KPGKNKRTAI
       190        200        210        220        230        240
TTPNFKKLHE AHFKEMESID QYIERKKKHF EEHNSMNELK QQPINKGGVR TPVPPRGRLS
       250        260        270        280        290        300
VASTPISQRR SQGRSCGPAS QSTLGLKGSL KRSAISAAKT GVRFSAATKD NEHKRSLTKT
       310        320        330        340        350        360
PARKSAHVTV SGGTPKGEAV LGTHKLKTIT GNSAAVITPF KLTTEATQTP VSNKKPVFDL
       370        380        390        400        410        420
KASLSRPLNY EPHKGKLKPW GQSKENNYLN QHVNRINFYK KTYKQPHLQT KEEQRKKREQ
       430        440
ERKEKKAKVL GMRRGLILAE D         10         20         30         40         50         60
MIIPSLEELD SLKYSDLQNL AKSLGLRANL RATKLLKALK GYIKHEARKG NENQDESQTS
        70         80         90        100        110        120
ASSCDETEIQ ISNQEEAERQ PLGHVTKTRR RCKTVRVDPD SQQNHSEIKI SNPTEFQNHE
       130        140        150        160        170        180
KQESQDLRAT AKVPSPPDEH QEAENAVSSG NRDSKVPSEG KKSLYTDESS KPGKNKRTAI
       190        200        210        220        230        240
TTPNFKKLHE AHFKEMESID QYIERKKKHF EEHNSMNELK QQPINKGGVR TPVPPRGRLS
       250        260        270        280        290        300
VASTPISQRR SQGRSCGPAS QSTLGLKGSL KRSAISAAKT GVRFSAATKD NEHKRSLTKT
       310        320        330        340        350        360
PARKSAHVTV SGGTPKGEAV LGTHKLKTIT GNSAAVITPF KLTTEATQTP VSNKKPVFDL
       370        380        390        400        410        420
KASLSRPLNY EPHKGKLKPW GQSKENNYLN QHVNRINFYK KTYKQPHLQT KEEQRKKREQ
       430        440
ERKEKKAKVL GMRRGLILAE D         10         20         30         40         50         60
MIIPSLEELD SLKYSDLQNL AKSLGLRANL RATKLLKALK GYIKHEARKG NENQDESQTS
        70         80         90        100        110        120
ASSCDETEIQ ISNQEEAERQ PLGHVTKTRR RCKTVRVDPD SQQNHSEIKI SNPTEFQNHE
       130        140        150        160        170        180
KQESQDLRAT AKVPSPPDEH QEAENAVSSG NRDSKVPSEG KKSLYTDESS KPGKNKRTAI
       190        200        210        220        230        240
TTPNFKKLHE AHFKEMESID QYIERKKKHF EEHNSMNELK QQPINKGGVR TPVPPRGRLS
       250        260        270        280        290        300
VASTPISQRR SQGRSCGPAS QSTLGLKGSL KRSAISAAKT GVRFSAATKD NEHKRSLTKT
       310        320        330        340        350        360
PARKSAHVTV SGGTPKGEAV LGTHKLKTIT GNSAAVITPF KLTTEATQTP VSNKKPVFDL
       370        380        390        400        410        420
KASLSRPLNY EPHKGKLKPW GQSKENNYLN QHVNRINFYK KTYKQPHLQT KEEQRKKREQ
       430        440
ERKEKKAKVL GMRRGLILAE D         10         20         30         40         50         60
MIIPSLEELD SLKYSDLQNL AKSLGLRANL RATKLLKALK GYIKHEARKG NENQDESQTS
        70         80         90        100        110        120
ASSCDETEIQ ISNQEEAERQ PLGHVTKTRR RCKTVRVDPD SQQNHSEIKI SNPTEFQNHE
       130        140        150        160        170        180
KQESQDLRAT AKVPSPPDEH QEAENAVSSG NRDSKVPSEG KKSLYTDESS KPGKNKRTAI
       190        200        210        220        230        240
TTPNFKKLHE AHFKEMESID QYIERKKKHF EEHNSMNELK QQPINKGGVR TPVPPRGRLS
       250        260        270        280        290        300
VASTPISQRR SQGRSCGPAS QSTLGLKGSL KRSAISAAKT GVRFSAATKD NEHKRSLTKT
       310        320        330        340        350        360
PARKSAHVTV SGGTPKGEAV LGTHKLKTIT GNSAAVITPF KLTTEATQTP VSNKKPVFDL
       370        380        390        400        410        420
KASLSRPLNY EPHKGKLKPW GQSKENNYLN QHVNRINFYK KTYKQPHLQT KEEQRKKREQ
       430        440
ERKEKKAKVL GMRRGLILAE D         10         20         30         40         50         60
MIIPSLEELD SLKYSDLQNL AKSLGLRANL RATKLLKALK GYIKHEARKG NENQDESQTS
        70         80         90        100        110        120
ASSCDETEIQ ISNQEEAERQ PLGHVTKTRR RCKTVRVDPD SQQNHSEIKI SNPTEFQNHE
       130        140        150        160        170        180
KQESQDLRAT AKVPSPPDEH QEAENAVSSG NRDSKVPSEG KKSLYTDESS KPGKNKRTAI
       190        200        210        220        230        240
TTPNFKKLHE AHFKEMESID QYIERKKKHF EEHNSMNELK QQPINKGGVR TPVPPRGRLS
       250        260        270        280        290        300
VASTPISQRR SQGRSCGPAS QSTLGLKGSL KRSAISAAKT GVRFSAATKD NEHKRSLTKT
       310        320        330        340        350        360
PARKSAHVTV SGGTPKGEAV LGTHKLKTIT GNSAAVITPF KLTTEATQTP VSNKKPVFDL
       370        380        390        400        410        420
KASLSRPLNY EPHKGKLKPW GQSKENNYLN QHVNRINFYK KTYKQPHLQT KEEQRKKREQ
       430        440
ERKEKKAKVL GMRRGLILAE D         10         20         30         40         50         60
MIIPSLEELD SLKYSDLQNL AKSLGLRANL RATKLLKALK GYIKHEARKG NENQDESQTS
        70         80         90        100        110        120
ASSCDETEIQ ISNQEEAERQ PLGHVTKTRR RCKTVRVDPD SQQNHSEIKI SNPTEFQNHE
       130        140        150        160        170        180
KQESQDLRAT AKVPSPPDEH QEAENAVSSG NRDSKVPSEG KKSLYTDESS KPGKNKRTAI
       190        200        210        220        230        240
TTPNFKKLHE AHFKEMESID QYIERKKKHF EEHNSMNELK QQPINKGGVR TPVPPRGRLS
       250        260        270        280        290        300
VASTPISQRR SQGRSCGPAS QSTLGLKGSL KRSAISAAKT GVRFSAATKD NEHKRSLTKT
       310        320        330        340        350        360
PARKSAHVTV SGGTPKGEAV LGTHKLKTIT GNSAAVITPF KLTTEATQTP VSNKKPVFDL
       370        380        390        400        410        420
KASLSRPLNY EPHKGKLKPW GQSKENNYLN QHVNRINFYK KTYKQPHLQT KEEQRKKREQ
       430        440
ERKEKKAKVL GMRRGLILAE D

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9BXS6-1-	MIIPSL...	1		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9BXS6-1-	MIIPSL...	1		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9BXS6-1-unknown	MIIPSL...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9BXS6-1-unknown	MIIPSL...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt83566
Q9BXS6-1-unknown	MIIPSL...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt83567
Q9BXS6-1-unknown	MIIPSL...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt83568
Q9BXS6-1-unknown	MIIPSL...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt83569
Q9BXS6-1-unknown	MIIPSL...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt83570
Q9BXS6-1-unknown	MIIPSL...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt83571
Q9BXS6-305-unknown	SAHVTV...	305		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9BXS6-305-unknown	SAHVTV...	305	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160012
Q9BXS6-305-unknown	SAHVTV...	305	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160015
Q9BXS6-305-unknown	SAHVTV...	305	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160013
Q9BXS6-305-unknown	SAHVTV...	305	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160016
Q9BXS6-305-unknown	SAHVTV...	305	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160014
Q9BXS6-305-unknown	SAHVTV...	305	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160017
Q9BXS6-305-	SAHVTV...	305		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ILAED	441	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...ILAED	441	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79189
...ILAED	441	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79186
...ILAED	441	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79188
...ILAED	441	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79185
...ILAED	441	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79184
...ILAED	441	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79187

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)