Q9BY42: Replication termination factor 2 {ECO:0000305}

General Information

Protein names	- Replication termination factor 2 {ECO:0000305} - RTF2 {ECO:0000305} - Replication termination factor 2 domain-containing protein 1 {ECO:0000305}
Gene names	RTFDC1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9BY42

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGCDGGTIPK RHELVKGPKK VEKVDKDAEL VAQWNYCTLS QEILRRPIVA CELGRLYNKD
        70         80         90        100        110        120
AVIEFLLDKS AEKALGKAAS HIKSIKNVTE LKLSDNPAWE GDKGNTKGDK HDDLQRARFI
       130        140        150        160        170        180
CPVVGLEMNG RHRFCFLRCC GCVFSERALK EIKAEVCHTC GAAFQEDDVI MLNGTKEDVD
       190        200        210        220        230        240
VLKTRMEERR LRAKLEKKTK KPKAAESVSK PDVSEEAPGP SKVKTGKPEE ASLDSREKKT
       250        260        270        280        290        300
NLAPKSTAMN ESSSGKAGKP PCGATKRSIA DSEESEAYKS LFTTHSSAKR SKEESAHWVT

HTSYCF

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9BY42-1-unknown	MGCDGG...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9BY42-2-unknown	GCDGGT...	2		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9BY42-2-unknown	GCDGGT...	2		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9BY42-268-	SIADSE...	268		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...APKSTA	247	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000400322
	...TSYCF	306	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)