Q9BZ23: Pantothenate kinase 2, mitochondrial

General Information

Protein names	- Pantothenate kinase 2, mitochondrial - hPanK2 - 2.7.1.33 - Pantothenic acid kinase 2
Gene names	PANK2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9BZ23

6 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 3 of Pantothenate kinase 2, mitochondrial - Isoform 2 of Pantothenate kinase 2, mitochondrial - Isoform 4 of Pantothenate kinase 2, mitochondrial

Sequence View

        10         20         30         40         50         60
MRRLGPFHPR VHWAAPPSLS SGLHRLLFLR GTRIPSSTTL SPPRHDSLSL DGGTVNPPRV
        70         80         90        100        110        120
REPTGREAFG PSPASSDWLP ARWRNGRGGR PRARLCSGWT AAEEARRNPT LGGLLGRQRL
       130        140        150        160        170        180
LLRMGGGRLG APMERHGRAS ATSVSSAGEQ AAGDPEGRRQ EPLRRRASSA SVPAVGASAE
       190        200        210        220        230        240
GTRRDRLGSY SGPTSVSRQR VESLRKKRPL FPWFGLDIGG TLVKLVYFEP KDITAEEEEE
       250        260        270        280        290        300
EVESLKSIRK YLTSNVAYGS TGIRDVHLEL KDLTLCGRKG NLHFIRFPTH DMPAFIQMGR
       310        320        330        340        350        360
DKNFSSLHTV FCATGGGAYK FEQDFLTIGD LQLCKLDELD CLIKGILYID SVGFNGRSQC
       370        380        390        400        410        420
YYFENPADSE KCQKLPFDLK NPYPLLLVNI GSGVSILAVY SKDNYKRVTG TSLGGGTFFG
       430        440        450        460        470        480
LCCLLTGCTT FEEALEMASR GDSTKVDKLV RDIYGGDYER FGLPGWAVAS SFGNMMSKEK
       490        500        510        520        530        540
REAVSKEDLA RATLITITNN IGSIARMCAL NENINQVVFV GNFLRINTIA MRLLAYALDY
       550        560        570
WSKGQLKALF SEHEGYFGAV GALLELLKIP         10         20         30         40         50         60
MRRLGPFHPR VHWAAPPSLS SGLHRLLFLR GTRIPSSTTL SPPRHDSLSL DGGTVNPPRV
        70         80         90        100        110        120
REPTGREAFG PSPASSDWLP ARWRNGRGGR PRARLCSGWT AAEEARRNPT LGGLLGRQRL
       130        140        150        160        170        180
LLRMGGGRLG APMERHGRAS ATSVSSAGEQ AAGDPEGRRQ EPLRRRASSA SVPAVGASAE
       190        200        210        220        230        240
GTRRDRLGSY SGPTSVSRQR VESLRKKRPL FPWFGLDIGG TLVKLVYFEP KDITAEEEEE
       250        260        270        280        290        300
EVESLKSIRK YLTSNVAYGS TGIRDVHLEL KDLTLCGRKG NLHFIRFPTH DMPAFIQMGR
       310        320        330        340        350        360
DKNFSSLHTV FCATGGGAYK FEQDFLTIGD LQLCKLDELD CLIKGILYID SVGFNGRSQC
       370        380        390        400        410        420
YYFENPADSE KCQKLPFDLK NPYPLLLVNI GSGVSILAVY SKDNYKRVTG TSLGGGTFFG
       430        440        450        460        470        480
LCCLLTGCTT FEEALEMASR GDSTKVDKLV RDIYGGDYER FGLPGWAVAS SFGNMMSKEK
       490        500        510        520        530        540
REAVSKEDLA RATLITITNN IGSIARMCAL NENINQVVFV GNFLRINTIA MRLLAYALDY
       550        560        570
WSKGQLKALF SEHEGYFGAV GALLELLKIP         10         20         30         40         50         60
MRRLGPFHPR VHWAAPPSLS SGLHRLLFLR GTRIPSSTTL SPPRHDSLSL DGGTVNPPRV
        70         80         90        100        110        120
REPTGREAFG PSPASSDWLP ARWRNGRGGR PRARLCSGWT AAEEARRNPT LGGLLGRQRL
       130        140        150        160        170        180
LLRMGGGRLG APMERHGRAS ATSVSSAGEQ AAGDPEGRRQ EPLRRRASSA SVPAVGASAE
       190        200        210        220        230        240
GTRRDRLGSY SGPTSVSRQR VESLRKKRPL FPWFGLDIGG TLVKLVYFEP KDITAEEEEE
       250        260        270        280        290        300
EVESLKSIRK YLTSNVAYGS TGIRDVHLEL KDLTLCGRKG NLHFIRFPTH DMPAFIQMGR
       310        320        330        340        350        360
DKNFSSLHTV FCATGGGAYK FEQDFLTIGD LQLCKLDELD CLIKGILYID SVGFNGRSQC
       370        380        390        400        410        420
YYFENPADSE KCQKLPFDLK NPYPLLLVNI GSGVSILAVY SKDNYKRVTG TSLGGGTFFG
       430        440        450        460        470        480
LCCLLTGCTT FEEALEMASR GDSTKVDKLV RDIYGGDYER FGLPGWAVAS SFGNMMSKEK
       490        500        510        520        530        540
REAVSKEDLA RATLITITNN IGSIARMCAL NENINQVVFV GNFLRINTIA MRLLAYALDY
       550        560        570
WSKGQLKALF SEHEGYFGAV GALLELLKIP

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name
Q9BZ23-47-unknown	SLSLDG...	47	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9BZ23-111-unknown	LGGLLG...	111	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q9BZ23-124-unknown	MGGGRL...	124	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt84217
Q9BZ23-124-unknown	MGGGRL...	124	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt109724
Q9BZ23-143-unknown	SVSSAG...	143	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt183221
Q9BZ23-143-unknown	SVSSAG...	143	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt183220
Q9BZ23-143-	SVSSAG...	143		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q9BZ23-292-unknown	MPAFIQ...	292	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt84216
Q9BZ23-292-unknown	MPAFIQ...	292	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt109657
Q9BZ23-292-unknown	MPAFIQ...	292	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt109656

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LLKIP	570	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LLKIP	570	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79834
...LLKIP	570	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79835
...LLKIP	570	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79836

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)