Q9CPY7: Cytosol aminopeptidase

General Information

Protein names	- Cytosol aminopeptidase - 3.4.11.1 - Leucine aminopeptidase 3 - LAP-3 - Leucyl aminopeptidase - Proline aminopeptidase - 3.4.11.5 - Prolyl aminopeptidase
Gene names	Lap3
Organism	Mus musculus
Protease Family
Protease ID	M17.001
Chromosome location
UniProt ID	Q9CPY7

9 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MYLLPLPAAA RVALRRLGVR GLWDRGLSTA DMTKGLVLGI YAKDKDDDLP QFTSAGESFN
        70         80         90        100        110        120
KLVSGKLREM LNISGPPLKA GKTRTFYGLH QDFPSVVVVG LGKRSAGVDD QENWHEGKEN
       130        140        150        160        170        180
IRAAVAAGCR QVQDLELPSV EVDPCGDAQA AAEGAVLGLY EYDDLKQKKK VAVSAKLHGS
       190        200        210        220        230        240
GDLEAWEKGV LFASGQNLAR HLMESPANEM TPTRFAEIIE KNLKSASSKT KVHIRPKSWI
       250        260        270        280        290        300
EEQEMGSFLS VAKGSEEPPV FLEIHYMGSP NATEAPLVFV GKGITFDSGG ISIKASANMD
       310        320        330        340        350        360
LMRADMGGAA TICSAIVSAA KLNLPINIIG LAPLCENMPS GKANKPGDVV RARNGKTIQV
       370        380        390        400        410        420
DNTDAEGRLI LADALCYAHT FNPKVIINAA TLTGAMDVAL GSGATGVFTN SSWLWNKLFE
       430        440        450        460        470        480
ASVETGDRVW RMPLFEHYTR QVIDCQLADV NNLGKYRSAG ACTAAAFLRE FVTHTKWAHL
       490        500        510
DIAGVMTNKD EIPYLRKGMS GRPTRTLIEF LLRFSKDSS

Isoforms

- Isoform 2 of Cytosol aminopeptidase

Sequence View

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Protein Neighborhood

Domains & Features

9 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9CPY7-1-unknown	MYLLPL...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9CPY7-32-unknown	MTKGLV...	32	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt66824
Q9CPY7-32-unknown	MTKGLV...	32	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q9CPY7-71-unknown	LNISGP...	71	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31003
Q9CPY7-71-unknown	LNISGP...	71	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt138313
Q9CPY7-72-unknown	NISGPP...	72	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31005
Q9CPY7-72-unknown	NISGPP...	72	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt138400
Q9CPY7-354-unknown	NGKTIQ...	354	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180915
Q9CPY7-354-unmodified	NGKTIQ...	354		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q9CPY7-357-unmodified	TIQVDN...	357		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q9CPY7-357-unknown	TIQVDN...	357	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180993
Q9CPY7-458-unknown	SAGACT...	458		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
Q9CPY7-458-unknown	SAGACT...	458	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160487

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KLREML	70	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31003
...KLREML	70	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt121346
...LREMLN	71	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31005
...LREMLN	71	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt121441
...SKDSS	519	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SKDSS	519	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt62442

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	70	REML.\|.LNIS	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> AMPL_MOUSE @70
CATE_MOUSE	71	EMLN.\|.NISG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> AMPL_MOUSE @71

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)