Q9CSU0: Regulation of nuclear pre-mRNA domain-containing protein 1B

General Information

Protein names	- Regulation of nuclear pre-mRNA domain-containing protein 1B - Cell cycle-related and expression-elevated protein in tumor
Gene names	Rprd1b
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9CSU0

6 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Regulation of nuclear pre-mRNA domain-containing protein 1B - Isoform 3 of Regulation of nuclear pre-mRNA domain-containing protein 1B

Sequence View

        10         20         30         40         50         60
MSSFSESALE KKLSELSNSQ QSVQTLSLWL IHHRKHAGPI VSVWHRELRK AKSNRKLTFL
        70         80         90        100        110        120
YLANDVIQNS KRKGPEFTRE FESVLVDAFS HVAREADEGC KKPLERLLNI WQERSVYGGE
       130        140        150        160        170        180
FIQQLKLSME DSKSPPPKAA EEKKSLKRTF QQIQEEEDDD YPGSYSPQDP SAGPLLTEEL
       190        200        210        220        230        240
IKALQDLENA ASGDATVRQK IASLPQEVQD VSLLEKITDK EAAERLSKTV DEACLLLAEY
       250        260        270        280        290        300
NGRLAAELED RRQLARMLVE YTQNQKEVLS EKEKKLEEYK QKLARVTQVR KELKSHIQSL
       310        320
PDLSLLPNVT GGLAPLPSAG DLFSTD         10         20         30         40         50         60
MSSFSESALE KKLSELSNSQ QSVQTLSLWL IHHRKHAGPI VSVWHRELRK AKSNRKLTFL
        70         80         90        100        110        120
YLANDVIQNS KRKGPEFTRE FESVLVDAFS HVAREADEGC KKPLERLLNI WQERSVYGGE
       130        140        150        160        170        180
FIQQLKLSME DSKSPPPKAA EEKKSLKRTF QQIQEEEDDD YPGSYSPQDP SAGPLLTEEL
       190        200        210        220        230        240
IKALQDLENA ASGDATVRQK IASLPQEVQD VSLLEKITDK EAAERLSKTV DEACLLLAEY
       250        260        270        280        290        300
NGRLAAELED RRQLARMLVE YTQNQKEVLS EKEKKLEEYK QKLARVTQVR KELKSHIQSL
       310        320
PDLSLLPNVT GGLAPLPSAG DLFSTD

Filter Information:

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q9CSU0-2-unknown	MSSFSE...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q9CSU0-2-unknown	MSSFSE...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9CSU0-1-unknown	MSSFSE...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt88196
Q9CSU0-1-unknown	MSSFSE...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt88197
Q9CSU0-2-Acetylation	SSFSES...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9CSU0-2-Acetylation	SSFSES...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110846
Q9CSU0-2-Acetylation	SSFSES...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110847
Q9CSU0-2-Acetylation	SSFSES...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q9CSU0-60-unknown	LYLAND...	60		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31024
Q9CSU0-60-unknown	LYLAND...	60		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt139888
Q9CSU0-60-unknown	LYLAND...	60		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt139889
Q9CSU0-61-unknown	YLANDV...	61		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31027
Q9CSU0-61-unknown	YLANDV...	61		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt139980
Q9CSU0-61-unknown	YLANDV...	61		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt139981
Q9CSU0-188-unknown	ENAASG...	188		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29334
Q9CSU0-188-unknown	ENAASG...	188		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt146186
Q9CSU0-188-unknown	ENAASG...	188		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt146187

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RKLTFL	59	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31024
...RKLTFL	59	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122993
...RKLTFL	59	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122994
...KLTFLY	60	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31027
...KLTFLY	60	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123086
...KLTFLY	60	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123087
...ALQDLE	187	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29334
...ALQDLE	187	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129488
...ALQDLE	187	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129489
...LFSTD	326	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
CATE_MOUSE	59	LTFL.\|.LYLA	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> RPR1B_MOUSE @59
CATE_MOUSE	60	TFLY.\|.YLAN	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> RPR1B_MOUSE @60
CATD_MOUSE	187	QDLE.\|.ENAA	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> RPR1B_MOUSE @187

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)